Dipeptidyl peptidase IV inhibitor sitagliptin reduces local inflammation in adipose tissue and in pancreatic islets of obese mice

Comparative effects of telmisartan, sitagliptin and metformin alone or in combination on obesity, insulin resistance, and liver and pancreas remodelling in C57BL/6 mice fed on a very high-fat diet

(2010) Vanessa Souza-Mello et al.   CLINICAL SCIENCE

Sitagliptin (MK0431) Inhibition of Dipeptidyl Peptidase IV Decreases Nonobese Diabetic Mouse CD4+ T-Cell Migration Through Incretin-Dependent and -Independent Pathways

(2010) S.-J. Kim et al.   DIABETES

Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet

(2010) J. A. Ehses et al.   DIABETOLOGIA

Dipeptidyl-Peptidase 4 and Attractin Expression is Increased in Circulating Blood Monocytes of Obese Human Subjects

(2010) M. Laudes et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Glucagon-Like Peptide-2 Receptor Modulates Islet Adaptation to Metabolic Stress in the ob/ob Mouse

(2010) Jasmine Bahrami et al.   GASTROENTEROLOGY

Valsartan Protects Pancreatic Islets and Adipose Tissue From the Inflammatory and Metabolic Consequences of a High-Fat Diet in Mice

(2010) Banumathi K. Cole et al.   HYPERTENSION

12-Lipoxygenase Products Reduce Insulin Secretion and β-Cell Viability in Human Islets

(2010) K. Ma et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Incretin-Based Therapies for Type 2 Diabetes Mellitus: Current Status and Future Prospects

(2010) Scott R Drab   PHARMACOTHERAPY

Cytokine production by islets in health and diabetes: cellular origin, regulation and function

(2010) Marc Y. Donath et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Increased secretion of IP-10 from monocytes under hyperglycemia is via the TLR2 and TLR4 pathway

(2009) Sridevi Devaraj et al.   CYTOKINE

DPP-IV inhibition enhances the antilipolytic action of NPY in human adipose tissue

(2009) K. Kos et al.   DIABETES OBESITY & METABOLISM

Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose and non-glucose induced insulin secretion in patients with type 2 diabetes mellitus

(2009) K. Aaboe et al.   DIABETES OBESITY & METABOLISM

IL6 as a mediator of insulin resistance: fat or fiction?

(2009) T. L. Allen et al.   DIABETOLOGIA

Inhibition of DPP-4 with sitagliptin improves glycemic control and restores islet cell mass and function in a rodent model of type 2 diabetes

(2009) James Mu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

(2009) Markus Feuerer et al.   NATURE MEDICINE

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

(2009) Satoshi Nishimura et al.   NATURE MEDICINE

Normalization of obesity-associated insulin resistance through immunotherapy

(2009) Shawn Winer et al.   NATURE MEDICINE

12/15-Lipoxygenase Products Induce Inflammation and Impair Insulin Signaling in 3T3-L1 Adipocytes

(2009) Swarup K. Chakrabarti et al.   Obesity

Islet Inflammation Impairs the Pancreatic β-Cell in Type 2 Diabetes

(2009) Marc Y. Donath et al.   PHYSIOLOGY

Hypertrophy and/or Hyperplasia: Dynamics of Adipose Tissue Growth

(2009) Junghyo Jo et al.   PLoS Computational Biology

Pancreatic islet inflammation in type 2 diabetes: From α and β cell compensation to dysfunction

(2009) Jan A. Ehses et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by western diet

(2008) Craig S. Nunemaker et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Adipose Tissue Lymphocytes and Macrophages in Obesity and Insulin Resistance

(2008) A. Bouloumié et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

T-lymphocyte Infiltration in Visceral Adipose Tissue

(2008) Ulrich Kintscher et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IL-12 serum levels in patients with type 2 diabetes treated with sulphonylureas

(2008) Małgorzata Wegner et al.   CYTOKINE

Islet Inflammation in Type 2 Diabetes: From metabolic stress to therapy

(2008) M. Y. Donath et al.   DIABETES CARE

Inflamed adipose tissue, insulin resistance and vascular injury

(2008) Christian X. Andersson et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Acute Dipeptidyl Peptidase-4 Inhibition Rapidly Enhances Insulin-Mediated Suppression of Endogenous Glucose Production in Mice

(2008) Hélène Duez et al.   ENDOCRINOLOGY

The Role of chemokines and chemokine receptors in diabetic nephropathy

(2007) Christiane Ruster   Frontiers in Bioscience-Landmark

Gene Expression of Purified β-Cell Tissue Obtained from Human Pancreas with Laser Capture Microdissection

(2007) Lorella Marselli et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM