Development of lactobionic acid conjugated-copper chelators as anticancer candidates for hepatocellular carcinoma

Synthesis and evaluation of novel thiosemicarbazone and semicarbazone analogs with both anti-proliferative and anti-metastatic activities against triple negative breast cancer

(2021) Chengfeng Bai et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A mononuclear copper(II) complex containing benzimidazole and pyridyl ligands: Synthesis, characterization, and antiproliferative activity against human cancer cells

(2019) Sedat Kacar et al.   Arabian Journal of Chemistry

Liver as a key organ in the supply, storage, and excretion of copper

(2018) Eve A Roberts et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Copper deposition in focal nodular hyperplasia and inflammatory hepatocellular adenoma

(2017) Vishal S Chandan et al.   JOURNAL OF CLINICAL PATHOLOGY

Efficient Liver Targeting by Polyvalent Display of a Compact Ligand for the Asialoglycoprotein Receptor

(2017) Carlos A. Sanhueza et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In vitro antitumor activity of water-soluble copper(I) complexes with diimine and monodentate phosphine ligands

(2017) Marina Porchia et al.   Arabian Journal of Chemistry

Well-Defined Multivalent Ligands for Hepatocytes Targeting via Asialoglycoprotein Receptor

(2016) Xiangang Huang et al.   BIOCONJUGATE CHEMISTRY

The rational design of specific SOD1 inhibitors via copper coordination and their application in ROS signaling research

(2016) Xiongwei Dong et al.   Chemical Science

Novel 2-aminoimidazole-4-one complexes of copper(II) and cobalt(II): Synthesis, structural characterization and cytotoxicity

(2016) Olga O. Krasnovskaya et al.   Arabian Journal of Chemistry

Elevated copper impairs hepatic nuclear receptor function in Wilson’s disease

(2015) Clavia Ruth Wooton-Kee et al.   JOURNAL OF CLINICAL INVESTIGATION

Wilson's disease and other neurological copper disorders

(2015) Oliver Bandmann et al.   LANCET NEUROLOGY

Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation

(2015) Jing Wang et al.   Nature Chemistry

Copper Signaling Axis as a Target for Prostate Cancer Therapeutics

(2014) R. Safi et al.   CANCER RESEARCH

Copper is required for oncogenic BRAF signalling and tumorigenesis

(2014) Donita C. Brady et al.   NATURE

Synthesis and antiproliferative activity of some steroidal thiosemicarbazones, semicarbazones and hydrozones

(2014) Chunfang Gan et al.   STEROIDS

Advances in Copper Complexes as Anticancer Agents

(2013) Carlo Santini et al.   CHEMICAL REVIEWS

Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery

(2013) Candice E. Paulsen et al.   CHEMICAL REVIEWS

Redox cycling of endogenous copper by thymoquinone leads to ROS-mediated DNA breakage and consequent cell death: putative anticancer mechanism of antioxidants

(2013) H Zubair et al.   Cell Death & Disease

Novel Chelators for Cancer Treatment: Where Are We Now?

(2012) Angelica M. Merlot et al.   ANTIOXIDANTS & REDOX SIGNALING

Asialoglycoprotein receptor (ASGPR) as target autoantigen in liver autoimmunity: Lost and found

(2012) Eirini I. Rigopoulou et al.   AUTOIMMUNITY REVIEWS

Glycomimetic Ligands for the Human Asialoglycoprotein Receptor

(2012) Sreeman K. Mamidyala et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Novel Role for Copper in Ras/Mitogen-Activated Protein Kinase Signaling

(2012) M. L. Turski et al.   MOLECULAR AND CELLULAR BIOLOGY

Copper complexes of bis(thiosemicarbazones): from chemotherapeutics to diagnostic and therapeutic radiopharmaceuticals

(2011) Brett M. Paterson et al.   CHEMICAL SOCIETY REVIEWS

Pathology of the Liver in Copper Overload

(2011) Melanie Johncilla et al.   SEMINARS IN LIVER DISEASE

Hepatocyte Targeting and Intracellular Copper Chelation by a Thiol-Containing Glycocyclopeptide

(2010) Anaïs M. Pujol et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Affinity gradients drive copper to cellular destinations

(2010) Lucia Banci et al.   NATURE

Copper Homeostasis: The Role of Cellular Transporters

(2010) Edward D. Harris   NUTRITION REVIEWS

Design, synthesis and biological evaluation of carbohydrate-functionalized cyclodextrins and liposomes for hepatocyte-specific targeting

(2010) Gonçalo J. L. Bernardes et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Thiosemicarbazones: the new wave in cancer treatment

(2009) Danuta S Kalinowski et al.   Future Medicinal Chemistry

Increasing Cu bioavailability inhibits A  oligomers and tau phosphorylation

(2009) P. J. Crouch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ligational behavior of thiosemicarbazone, semicarbazone and thiocarbohydrazone ligands towards VO(IV), Ce(III), Th(IV) and UO2(VI) ions: Synthesis, structural characterization and biological studies

(2009) M. Shebl et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Elevated copper and oxidative stress in cancer cells as a target for cancer treatment

(2008) Anshul Gupte et al.   CANCER TREATMENT REVIEWS

Mechanisms for copper acquisition, distribution and regulation

(2008) Byung-Eun Kim et al.   Nature Chemical Biology

Targeted Delivery of Macromolecular Drugs: Asialoglycoprotein Receptor (ASGPR) Expression by Selected Hepatoma Cell Lines used in Antiviral Drug Development

(2008) Yan Li et al.   Current Drug Delivery