Monoclonal antibody targeting BDCA2 ameliorates skin lesions in systemic lupus erythematosus

Anifrolumab, an Anti-Interferon-α Receptor Monoclonal Antibody, in Moderate-to-Severe Systemic Lupus Erythematosus

(2017) Richard Furie et al.   Arthritis & Rheumatology

Interferon (IFN)-λ Takes the Helm: Immunomodulatory Roles of Type III IFNs

(2017) Ivan Zanoni et al.   Frontiers in Immunology

Sifalimumab, an anti-interferon-α monoclonal antibody, in moderate to severe systemic lupus erythematosus: a randomised, double-blind, placebo-controlled study

(2016) Munther Khamashta et al.   ANNALS OF THE RHEUMATIC DISEASES

Cause and consequences of the activated type I interferon system in SLE

(2016) Maija-Leena Eloranta et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Cutaneous characteristics and association with antinuclear antibodies in 402 patients with different subtypes of lupus erythematosus

(2016) N. Patsinakidis et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

New insights into the immunopathogenesis of systemic lupus erythematosus

(2016) George C. Tsokos et al.   Nature Reviews Rheumatology

Anti-BDCA2 monoclonal antibody inhibits plasmacytoid dendritic cell activation through Fc-dependent and Fc-independent mechanisms

(2015) A. Pellerin et al.   EMBO Molecular Medicine

A Plasmacytoid Dendritic Cells-Type I Interferon Axis Is Critically Implicated in the Pathogenesis of Systemic Lupus Erythematosus

(2015) Ji-Min Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeting of type I interferon in systemic autoimmune diseases

(2015) Mary K. Crow et al.   Translational Research

Optimizing outcome in SLE: treating-to-target and definition of treatment goals

(2014) Andrea Doria et al.   AUTOIMMUNITY REVIEWS

Advances in understanding the role of type I interferons in systemic lupus erythematosus

(2014) Mary K. Crow   CURRENT OPINION IN RHEUMATOLOGY

Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model

(2014) Sarah L. Rowland et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetic evidence for the role of plasmacytoid dendritic cells in systemic lupus erythematosus

(2014) Vanja Sisirak et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Burden of corticosteroid use in patients with systemic lupus erythematosus: results from a Delphi panel

(2014) M Petri et al.   LUPUS

The Immunopathology of Cutaneous Lupus Erythematosus

(2014) Mark G. Kirchhof et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Epicutaneous Application of Toll-like Receptor 7 Agonists Leads to Systemic Autoimmunity in Wild-Type Mice: A New Model of Systemic Lupus Erythematosus

(2013) Maki Yokogawa et al.   Arthritis & Rheumatology

The interferon-regulated gene signature is elevated in subacute cutaneous lupus erythematosus and discoid lupus erythematosus and correlates with the cutaneous lupus area and severity index score

(2012) I. Braunstein et al.   BRITISH JOURNAL OF DERMATOLOGY

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

(2012) Kelvin C. Luk et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Taming lupus—a new understanding of pathogenesis is leading to clinical advances

(2012) Zheng Liu et al.   NATURE MEDICINE

Development of the CLASI as a Tool to Measure Disease Severity and Responsiveness to Therapy in Cutaneous Lupus Erythematosus

(2011) Rachel Klein et al.   ARCHIVES OF DERMATOLOGY

Current and novel therapeutics in the treatment of systemic lupus erythematosus

(2011) Cagri Yildirim-Toruner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

BDCA-2 signaling inhibits TLR-9-agonist-induced plasmacytoid dendritic cell activation and antigen presentation

(2010) Peter S. Jähn et al.   CELLULAR IMMUNOLOGY

Plasmacytoid dendritic cells: an overview of their presence and distribution in different inflammatory skin diseases, with special emphasis on Jessner's lymphocytic infiltrate of the skin and cutaneous lupus erythematosus

(2010) Dario Tomasini et al.   JOURNAL OF CUTANEOUS PATHOLOGY

Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9

(2010) Cristiana Guiducci et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutaneous distribution of plasmacytoid dendritic cells in lupus erythematosus. Selective tropism at the site of epithelial apoptotic damage

(2009) William Vermi et al.   IMMUNOBIOLOGY

Systemic Lupus Erythematosus

(2008) Anisur Rahman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immature myeloid and plasmacytoid dendritic cells infiltrate renal tubulointerstitium in patients with lupus nephritis

(2007) Nicoletta Fiore et al.   MOLECULAR IMMUNOLOGY