Implication of the APP Gene in Intellectual Abilities

Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia

(2016) S P Hagenaars et al.   MOLECULAR PSYCHIATRY

Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151)

(2016) G Davies et al.   MOLECULAR PSYCHIATRY

Arc is a flexible modular protein capable of reversible self-oligomerization

(2015) Craig Myrum et al.   BIOCHEMICAL JOURNAL

Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)

(2015) G Davies et al.   MOLECULAR PSYCHIATRY

HaploReg v4: systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and disease

(2015) Lucas D. Ward et al.   NUCLEIC ACIDS RESEARCH

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

Common variants in theARCgene are not associated with cognitive abilities

(2015) Craig Myrum et al.   Brain and Behavior

A fine balance: Regulation of hippocampal Arc/Arg3.1 transcription, translation and degradation in a rat model of normal cognitive aging

(2014) Bonnie R. Fletcher et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins

(2014) W D Hill et al.   Translational Psychiatry

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

Integration of biological networks and pathways with genetic association studies

(2012) Yan V. Sun   HUMAN GENETICS

Cohort Profile: The ‘Children of the 90s’—the index offspring of the Avon Longitudinal Study of Parents and Children

(2012) Andy Boyd et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

(2012) Thorlakur Jonsson et al.   NATURE

Arc/Arg3.1 Regulates an Endosomal Pathway Essential for Activity-Dependent β-Amyloid Generation

(2011) Jing Wu et al.   CELL

Genome-wide association studies establish that human intelligence is highly heritable and polygenic

(2011) G Davies et al.   MOLECULAR PSYCHIATRY

De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia

(2011) G Kirov et al.   MOLECULAR PSYCHIATRY

New views of Arc, a master regulator of synaptic plasticity

(2011) Jason D Shepherd et al.   NATURE NEUROSCIENCE

Arc in synaptic plasticity: from gene to behavior

(2011) Erica Korb et al.   TRENDS IN NEUROSCIENCES

The Angelman Syndrome Protein Ube3A Regulates Synapse Development by Ubiquitinating Arc

(2010) Paul L. Greer et al.   CELL

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

(2010) Yun Li et al.   GENETIC EPIDEMIOLOGY

Transcription factor Late SV40 Factor (LSF) functions as an oncogene in hepatocellular carcinoma

(2010) B. K. Yoo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Down syndrome--recent progress and future prospects

(2009) F. K. Wiseman et al.   HUMAN MOLECULAR GENETICS

Common Genetic Variation and Human Traits

(2009) David B. Goldstein   NEW ENGLAND JOURNAL OF MEDICINE

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

(2009) David Moher et al.   PLOS MEDICINE

The Arc of synaptic memory

(2009) Clive R. Bramham et al.   EXPERIMENTAL BRAIN RESEARCH

Estimated pre-morbid IQ effects on cognitive and functional outcomes in Alzheimer disease: a longitudinal study in a treated cohort

(2008) John M Starr et al.   BMC Psychiatry

Testing replication of a 5-SNP set for general cognitive ability in six population samples

(2008) Michelle Luciano et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Heritability in the genomics era — concepts and misconceptions

(2008) Peter M. Visscher et al.   NATURE REVIEWS GENETICS

PSEN1 polymorphisms alter the rate of cognitive decline in sporadic Alzheimer's disease patients

(2008) Olivia Belbin et al.   NEUROBIOLOGY OF AGING