Restructured Mitochondrial-Nuclear Interaction in Plasmodium falciparum Dormancy and Persister Survival after Artemisinin Exposure

Mycotoxin Altertoxin II Induces Lipid Peroxidation Connecting Mitochondrial Stress Response to NF-κB Inhibition in THP-1 Macrophages

(2020) Giorgia Del Favero et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13

(2020) Nina F. Gnädig et al.   PLoS Pathogens

‘Artemisinin Resistance’: Something New or Old? Something of a Misnomer?

(2020) Thomas E. Wellems et al.   TRENDS IN PARASITOLOGY

Dormant Plasmodium falciparum Parasites in Human Infections Following Artesunate Therapy

(2020) Christopher Peatey et al.   JOURNAL OF INFECTIOUS DISEASES

Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility

(2020) Clare R. Harding et al.   Nature Communications

Mitochondria form contact sites with the nucleus to couple prosurvival retrograde response

(2020) Radha Desai et al.   Science Advances

Evolution of resistance in vitro reveals mechanisms of artemisinin activity inToxoplasma gondii

(2019) Alex Rosenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kelch Mutations in Plasmodium falciparum Protein K13 Do Not Modulate Dormancy after Artemisinin Exposure and Sorbitol Selection In Vitro

(2018) Kimberly F. Breglio et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Phytohormones, Isoprenoids, and Role of the Apicoplast in Recovery from Dihydroartemisinin-Induced Dormancy of Plasmodium falciparum

(2018) Marvin Duvalsaint et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Melatonin activate FIS1, DYN1 and DYN2 Plasmodium falciparum related-genes for mitochondria fission: mitoemerald-GFP as a tool to visualize mitochondria structure

(2018) Pedro Scarpelli et al.   JOURNAL OF PINEAL RESEARCH

Fit-free analysis of fluorescence lifetime imaging data using the phasor approach

(2018) Suman Ranjit et al.   Nature Protocols

Artemisinin resistance phenotypes and K13 inheritance in a Plasmodium falciparum cross and Aotus model

(2018) Juliana M. Sá et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic fingerprinting of bacteria by fluorescence lifetime imaging microscopy

(2017) Arunima Bhattacharjee et al.   Scientific Reports

Alternative methods for the Plasmodium falciparum artemisinin ring-stage survival assay with increased simplicity and parasite stage-specificity

(2016) Whitney A. Kite et al.   MALARIA JOURNAL

Imaging mitochondrial dynamics in human skin reveals depth-dependent hypoxia and malignant potential for diagnosis

(2016) D. Pouli et al.   Science Translational Medicine

Correlation between Cyclin Dependent Kinases and Artemisinin-Induced Dormancy in Plasmodium falciparum In Vitro

(2016) Karen-Ann Gray et al.   PLoS One

Mitochondrial Membrane Potential in a Small Subset of Artemisinin-Induced DormantPlasmodium falciparumParasites In Vitro

(2015) Christopher L. Peatey et al.   JOURNAL OF INFECTIOUS DISEASES

A nuclear role for the respiratory enzyme CLK-1 in regulating mitochondrial stress responses and longevity

(2015) Richard M. Monaghan et al.   NATURE CELL BIOLOGY

Fatty Acid Synthesis and Pyruvate Metabolism Pathways Remain Active in Dihydroartemisinin-Induced Dormant Ring Stages of Plasmodium falciparum

(2014) Nanhua Chen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Flow Cytometry-Based Analysis of Artemisinin-Resistant Plasmodium falciparum in the Ring-Stage Survival Assay

(2014) Chanaki Amaratunga et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Rapid kill of malaria parasites by artemisinin and semi-synthetic endoperoxides involves ROS-dependent depolarization of the membrane potential

(2013) Thomas Antoine et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

(2013) Frédéric Ariey et al.   NATURE

Artemisinin-resistant Plasmodium falciparum in Pursat province, western Cambodia: a parasite clearance rate study

(2012) Chanaki Amaratunga et al.   LANCET INFECTIOUS DISEASES

Phenotypic and Genotypic Analysis ofIn Vitro-Selected Artemisinin-Resistant Progeny of Plasmodium falciparum

(2011) Matthew S. Tucker et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effects of Artesunate on Parasite Recrudescence and Dormancy in the Rodent Malaria Model Plasmodium vinckei

(2011) Alexis N. LaCrue et al.   PLoS One

Phasor approach to fluorescence lifetime microscopy distinguishes different metabolic states of germ cells in a live tissue

(2011) C. Stringari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A rapid and robust tri-color flow cytometry assay for monitoring malaria parasite development

(2011) Benoît Malleret et al.   Scientific Reports

Fluorescence Lifetime Measurements and Biological Imaging

(2010) Mikhail Y. Berezin et al.   CHEMICAL REVIEWS

The Role of Heme and the Mitochondrion in the Chemical and Molecular Mechanisms of Mammalian Cell Death Induced by the Artemisinin Antimalarials

(2010) Amy E. Mercer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Artemisinin‐Induced Dormancy inPlasmodium falciparum: Duration, Recovery Rates, and Implications in Treatment Failure

(2010) Franka Teuscher et al.   JOURNAL OF INFECTIOUS DISEASES

Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial

(2010) Arjen M Dondorp et al.   LANCET

Artemisinin Directly Targets Malarial Mitochondria through Its Specific Mitochondrial Activation

(2010) Juan Wang et al.   PLoS One

Erythrocyte Binding Protein PfRH5 Polymorphisms Determine Species-Specific Pathways of Plasmodium falciparum Invasion

(2008) Karen Hayton et al.   Cell Host & Microbe

The Phasor Approach to Fluorescence Lifetime Imaging Analysis

(2007) Michelle A. Digman et al.   BIOPHYSICAL JOURNAL