Proline metabolism as regulatory hub

Target of Rapamycin Signaling in Plant Stress Responses

(2020) Liwen Fu et al.   PLANT PHYSIOLOGY

Sink/Source Balance of Leaves Influences Amino Acid Pools and Their Associated Metabolic Fluxes in Winter Oilseed Rape (Brassica napus L.)

(2020) Younès Dellero et al.   Metabolites

The N-terminal domain of Arabidopsis proline dehydrogenase affects enzymatic activity and protein oligomerization

(2020) Georgina Fabro et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Differential Contribution of P5CS Isoforms to Stress Tolerance in Arabidopsis

(2020) Dietmar Funck et al.   Frontiers in Plant Science

Proline is a quencher of singlet oxygen and superoxide both in in vitro systems and isolated thylakoids

(2020) Ateeq Ur Rehman et al.   PHYSIOLOGIA PLANTARUM

Appropriate Activity Assays Are Crucial for the Specific Determination of Proline Dehydrogenase and Pyrroline-5-Carboxylate Reductase Activities

(2020) Sandrine Lebreton et al.   Frontiers in Plant Science

The role of amino acid metabolism during abiotic stress release

(2019) Willian Batista-Silva et al.   PLANT CELL AND ENVIRONMENT

Linking Autophagy to Abiotic and Biotic Stress Responses

(2019) Santiago Signorelli et al.   TRENDS IN PLANT SCIENCE

Evolution of TOR-SnRK dynamics in green plants and its integration with phytohormone signaling networks

(2019) Muhammed Jamsheer K et al.   JOURNAL OF EXPERIMENTAL BOTANY

Target of Rapamycin kinase: central regulatory hub for plant growth and metabolism

(2019) Lyubov A Ryabova et al.   JOURNAL OF EXPERIMENTAL BOTANY

Proline oxidation fuels mitochondrial respiration during dark-induced leaf senescence in Arabidopsis thaliana

(2019) Alban Launay et al.   JOURNAL OF EXPERIMENTAL BOTANY

Leaf status and environmental signals jointly regulate proline metabolism in winter oilseed rape

(2019) Younes Dellero et al.   JOURNAL OF EXPERIMENTAL BOTANY

Metabolite Regulatory Interactions Control Plant Respiratory Metabolism via Target of Rapamycin (TOR) Kinase Activation

(2019) Brendan M. O’Leary et al.   PLANT CELL

Light Control of Salt-Induced Proline Accumulation Is Mediated by ELONGATED HYPOCOTYL 5 in Arabidopsis

(2019) Hajnalka Kovács et al.   Frontiers in Plant Science

Autophagy: The Master of Bulk and Selective Recycling

(2018) Richard S. Marshall et al.   Annual Review of Plant Biology

Functional FRIGIDA allele enhances drought tolerance by regulating the P5CS1 pathway in Arabidopsis thaliana

(2018) Qian Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Proline Cycle As a Potential Cancer Therapy Target

(2018) John J. Tanner et al.   BIOCHEMISTRY

The Arabidopsis bZIP transcription factor family — an update

(2018) Wolfgang Dröge-Laser et al.   CURRENT OPINION IN PLANT BIOLOGY

Snf1-RELATED KINASE1-Controlled C/S1-bZIP Signaling Activates Alternative Mitochondrial Metabolic Pathways to Ensure Plant Survival in Extended Darkness

(2018) Lorenzo Pedrotti et al.   PLANT CELL

Darkened leaves use different metabolic strategies for senescence and survival

(2018) Simon R Law et al.   PLANT PHYSIOLOGY

DFR1-Mediated Inhibition of Proline Degradation Pathway Regulates Drought and Freezing Tolerance in Arabidopsis

(2018) Yongbing Ren et al.   Cell Reports

Proline synthesis in developing microspores is required for pollen development and fertility

(2018) Roberto Mattioli et al.   BMC PLANT BIOLOGY

Biological Roles of Ornithine Aminotransferase (OAT) in Plant Stress Tolerance: Present Progress and Future Perspectives

(2018) Alia Anwar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Control of proline accumulation under drought via a novel pathway comprising the histone methylase CAU1 and the transcription factor ANAC055

(2017) Yanlei Fu et al.   JOURNAL OF EXPERIMENTAL BOTANY

Proline Accumulation Is Regulated by Transcription Factors Associated with Phosphate Starvation

(2017) Dávid Aleksza et al.   PLANT PHYSIOLOGY

Combinatorial interaction network of abscisic acid receptors and coreceptors fromArabidopsis thaliana

(2017) Stefanie V. Tischer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arabidopsis AMINO ACID PERMEASE1 Contributes to Salt Stress-Induced Proline Uptake from Exogenous Sources

(2017) Ting Wang et al.   Frontiers in Plant Science

TOR-Dependent and -Independent Pathways Regulate Autophagy in Arabidopsis thaliana

(2017) Yunting Pu et al.   Frontiers in Plant Science

SnRK1 activates autophagy via the TOR signaling pathway in Arabidopsis thaliana

(2017) Junmarie Soto-Burgos et al.   PLoS One

Transcriptome changes in Arabidopsis thaliana infected with Pseudomonas syringae during drought recovery

(2017) Aarti Gupta et al.   Scientific Reports

Proline Metabolism in Cell Regulation and Cancer Biology: Recent Advances and Hypotheses

(2017) James M. Phang   ANTIOXIDANTS & REDOX SIGNALING

TOR Signaling and Nutrient Sensing

(2016) Thomas Dobrenel et al.   Annual Review of Plant Biology

Proteomic and functional analysis of proline dehydrogenase 1 link proline catabolism to mitochondrial electron transport in Arabidopsis thaliana

(2016) C. Cabassa-Hourton et al.   BIOCHEMICAL JOURNAL

In vivo and in vitro approaches demonstrate proline is not directly involved in the protection against superoxide, nitric oxide, nitrogen dioxide and peroxynitrite

(2016) Santiago Signorelli et al.   FUNCTIONAL PLANT BIOLOGY

The Multifaceted Roles of HY5 in Plant Growth and Development

(2016) Sreeramaiah N. Gangappa et al.   Molecular Plant

Differential control and function of Arabidopsis ProDH1 and ProDH2 genes on infection with biotrophic and necrotrophic pathogens

(2016) Yanina Soledad Rizzi et al.   MOLECULAR PLANT PATHOLOGY

Arabidopsis Proline Dehydrogenase Contributes to Flagellin-Mediated PAMP-Triggered Immunity by Affecting RBOHD

(2016) Georgina Fabro et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Magnaporthe oryzae Effector AVR-Pii Helps to Establish Compatibility by Inhibition of the Rice NADP-Malic Enzyme Resulting in Disruption of Oxidative Burst and Host Innate Immunity

(2016)   MOLECULES AND CELLS

Early changes in apoplast composition associated with defence and disease in interactions betweenPhaseolus vulgarisand the halo blight pathogenPseudomonas syringaePv. phaseolicola

(2016) Brendan M. O'Leary et al.   PLANT CELL AND ENVIRONMENT

Light affects salt stress-induced transcriptional memory ofP5CS1inArabidopsis

(2016) Xuan Jun Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A transcription factor hierarchy defines an environmental stress response network

(2016) L. Song et al.   SCIENCE

Molecular Insights into the Enigmatic Metabolic Regulator, SnRK1

(2016) Shane Emanuelle et al.   TRENDS IN PLANT SCIENCE

Phytochrome and retrograde signalling pathways converge to antagonistically regulate a light-induced transcriptional network

(2016) Guiomar Martín et al.   Nature Communications

Proline Catabolism Modulates Innate Immunity in Caenorhabditis elegans

(2016) Haiqing Tang et al.   Cell Reports

The Arabidopsis transcription factor ABIG1 relays ABA signaled growth inhibition and drought induced senescence

(2016) Tie Liu et al.   eLife

The Fermentation Analogy: A Point of View for Understanding the Intriguing Role of Proline Accumulation in Stressed Plants

(2016) Santiago Signorelli   Frontiers in Plant Science

Proline affects the size of the root meristematic zone in Arabidopsis

(2015) Marco Biancucci et al.   BMC PLANT BIOLOGY

Deficient plastidic fatty acid synthesis triggers cell death by modulating mitochondrial reactive oxygen species

(2015) Jian Wu et al.   CELL RESEARCH

Photosynthetic light reactions: integral to chloroplast retrograde signalling

(2015) Peter J Gollan et al.   CURRENT OPINION IN PLANT BIOLOGY

A Novel Role of Proline Oxidase in HIV-1 Envelope Glycoprotein-induced Neuronal Autophagy

(2015) Jui Pandhare et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Photosynthetic lesions can trigger accelerated senescence inArabidopsis thaliana

(2015) Jing Wang et al.   JOURNAL OF EXPERIMENTAL BOTANY

Hydrogen peroxide produced by NADPH oxidases increases proline accumulation during salt or mannitol stress inArabidopsis thaliana

(2015) Kilani Ben Rejeb et al.   NEW PHYTOLOGIST

Crosstalk between Two bZIP Signaling Pathways Orchestrates Salt-Induced Metabolic Reprogramming in Arabidopsis Roots

(2015) Laura Hartmann et al.   PLANT CELL

SNAC-As, stress-responsive NAC transcription factors, mediate ABA-inducible leaf senescence

(2015) Hironori Takasaki et al.   PLANT JOURNAL

Proline over-accumulation alleviates salt stress and protects photosynthetic and antioxidant enzyme activities in transgenic sorghum [Sorghum bicolor (L.) Moench]

(2015) P. Surender Reddy et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

SnRK1-triggered switch of bZIP63 dimerization mediates the low-energy response in plants

(2015) Andrea Mair et al.   eLife

P5CDH affects the pathways contributing to Pro synthesis after ProDH activation by biotic and abiotic stress conditions

(2015) Yanina S. Rizzi et al.   Frontiers in Plant Science

Evolution of plant δ1-pyrroline-5-carboxylate reductases from phylogenetic and structural perspectives

(2015) Giuseppe Forlani et al.   Frontiers in Plant Science

The structure of Medicago truncatula δ1-pyrroline-5-carboxylate reductase provides new insights into regulation of proline biosynthesis in plants

(2015) Milosz Ruszkowski et al.   Frontiers in Plant Science

Role of proline and pyrroline-5-carboxylate metabolism in plant defense against invading pathogens

(2015) Aarzoo Qamar   Frontiers in Plant Science

Connecting proline metabolism and signaling pathways in plant senescence

(2015) Lu Zhang et al.   Frontiers in Plant Science

Evolution of proline biosynthesis: enzymology, bioinformatics, genetics, and transcriptional regulation

(2014) Yosef Fichman et al.   BIOLOGICAL REVIEWS

Context of action of Proline Dehydrogenase (ProDH) in the Hypersensitive Response of Arabidopsis

(2014) Mariela Monteoliva et al.   BMC PLANT BIOLOGY

Biochemical characterization of proline dehydrogenase in Arabidopsis mitochondria

(2014) Peter Schertl et al.   FEBS Journal

Balancing act: matching growth with environment by the TOR signalling pathway

(2014) Rossana Henriques et al.   JOURNAL OF EXPERIMENTAL BOTANY

The Interaction of the Arabidopsis Response Regulator ARR18 with bZIP63 Mediates the Regulation of PROLINE DEHYDROGENASE Expression

(2014) Manikandan Veerabagu et al.   Molecular Plant

Δ1-pyrroline-5-carboxylate reductase fromArabidopsis thaliana: stimulation or inhibition by chloride ions and feedback regulation by proline depend on whether NADPH or NADH acts as co-substrate

(2014) Samuele Giberti et al.   NEW PHYTOLOGIST

FourArabidopsis AREB/ABF transcription factors function predominantly in gene expression downstream of SnRK2 kinases in abscisic acid signalling in response to osmotic stress

(2014) TAKUYA YOSHIDA et al.   PLANT CELL AND ENVIRONMENT

The Arabidopsis transcription factor bZIP11 activates auxin-mediated transcription by recruiting the histone acetylation machinery

(2014) Christoph Weiste et al.   Nature Communications

Multiple roles of the transcription factor AtMYBR1/AtMYB44 in ABA signaling, stress responses, and leaf senescence

(2013) Masrur R Jaradat et al.   BMC PLANT BIOLOGY

Molecular Mechanisms for the Reaction Between •OH Radicals and Proline: Insights on the Role as Reactive Oxygen Species Scavenger in Plant Stress

(2013) Santiago Signorelli et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Is proline accumulationper secorrelated with stress tolerance or is proline homeostasis a more critical issue?

(2013) POLAVARAPU B. KAVI KISHOR et al.   PLANT CELL AND ENVIRONMENT

Genome-Wide Association Mapping Combined with Reverse Genetics Identifies New Effectors of Low Water Potential-Induced Proline Accumulation in Arabidopsis

(2013) P. E. Verslues et al.   PLANT PHYSIOLOGY

Proline does not quench singlet oxygen: Evidence to reconsider its protective role in plants

(2013) Santiago Signorelli et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

NUCLEAR FACTOR Y Transcription Factors Have Both Opposing and Additive Roles in ABA-Mediated Seed Germination

(2013) Roderick W. Kumimoto et al.   PLoS One

Proline dehydrogenase (oxidase), a mitochondrial tumor suppressor, and autophagy under the hypoxia microenvironment

(2012) Wei Liu et al.   Autophagy

Phosphorylation of the zinc finger transcriptional regulator ZAT6 by MPK6 regulates Arabidopsis seed germination under salt and osmotic stress

(2012) Xiao-Min Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Proline is required for male gametophyte development in Arabidopsis

(2012) Roberto Mattioli et al.   BMC PLANT BIOLOGY

Requirement of proline synthesis during Arabidopsis reproductive development

(2012) Dietmar Funck et al.   BMC PLANT BIOLOGY

Impaired Insulin/IGF1 Signaling Extends Life Span by Promoting Mitochondrial L-Proline Catabolism to Induce a Transient ROS Signal

(2012) Kim Zarse et al.   Cell Metabolism

The proline metabolism intermediate Δ1-pyrroline-5-carboxylate directly inhibits the mitochondrial respiration in budding yeast

(2012) Akira Nishimura et al.   FEBS LETTERS

Loss of cytosolic NADP-malic enzyme 2 in Arabidopsis thaliana is associated with enhanced susceptibility to Colletotrichum higginsianum

(2012) Lars M. Voll et al.   NEW PHYTOLOGIST

Pipecolic Acid, an Endogenous Mediator of Defense Amplification and Priming, Is a Critical Regulator of Inducible Plant Immunity

(2012) H. Navarova et al.   PLANT CELL

Ornithine-delta-aminotransferase and proline dehydrogenase genes play a role in non-host disease resistance by regulating pyrroline-5-carboxylate metabolism-induced hypersensitive response

(2012) MUTHAPPA SENTHIL-KUMAR et al.   PLANT CELL AND ENVIRONMENT

The Arabidopsis B-type response regulator 18 homomerizes and positively regulates cytokinin responses

(2012) Manikandan Veerabagu et al.   PLANT JOURNAL

Unique Drought Resistance Functions of the Highly ABA-Induced Clade A Protein Phosphatase 2Cs

(2012) G. B. Bhaskara et al.   PLANT PHYSIOLOGY

Intron-mediated alternative splicing of Arabidopsis P5CS1 and its association with natural variation in proline and climate adaptation

(2012) R. Kesari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MATH/BTB CRL3 Receptors Target the Homeodomain-Leucine Zipper ATHB6 to Modulate Abscisic Acid Signaling

(2011) E. Lechner et al.   DEVELOPMENTAL CELL

Proline dehydrogenase: a key enzyme in controlling cellular homeostasis

(2011) Caroline Servet   Frontiers in Bioscience-Landmark

Multiple strategies to prevent oxidative stress in Arabidopsis plants lacking the malate valve enzyme NADP-malate dehydrogenase

(2011) Inga Hebbelmann et al.   JOURNAL OF EXPERIMENTAL BOTANY

Heterodimers of theArabidopsisTranscription Factors bZIP1 and bZIP53 Reprogram Amino Acid Metabolism during Low Energy Stress

(2011) Katrin Dietrich et al.   PLANT CELL

Coordination of a mitochondrial superoxide burst during the hypersensitive response to bacterial pathogen in Nicotiana tabacum

(2011) MARINA CVETKOVSKA et al.   PLANT CELL AND ENVIRONMENT

ACCELERATED CELL DEATH 2 suppresses mitochondrial oxidative bursts and modulates cell death in Arabidopsis

(2011) Gopal K. Pattanayak et al.   PLANT JOURNAL

AtRbohF is a crucial modulator of defence-associated metabolism and a key actor in the interplay between intracellular oxidative stress and pathogenesis responses in Arabidopsis

(2011) Sejir Chaouch et al.   PLANT JOURNAL

Essential Role of Tissue-Specific Proline Synthesis and Catabolism in Growth and Redox Balance at Low Water Potential

(2011) Sandeep Sharma et al.   PLANT PHYSIOLOGY

Proline Dehydrogenase Contributes to Pathogen Defense in Arabidopsis

(2011) N. M. Cecchini et al.   PLANT PHYSIOLOGY

Proline Accumulation Is Inhibitory to Arabidopsis Seedlings during Heat Stress

(2011) W.-T. Lv et al.   PLANT PHYSIOLOGY

Elevation of free proline and proline-rich protein levels by simultaneous manipulations of proline biosynthesis and degradation in plants

(2011) Hanan Stein et al.   PLANT SCIENCE

Mitochondrial complex II has a key role in mitochondrial-derived reactive oxygen species influence on plant stress gene regulation and defense

(2011) C. Gleason et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proline metabolism and transport in plant development

(2010) Silke Lehmann et al.   AMINO ACIDS

Proline and Glycinebetaine Ameliorated NaCl StressviaScavenging of Hydrogen Peroxide and Methylglyoxal but Not Superoxide or Nitric Oxide in Tobacco Cultured Cells

(2010) Mst. Nasrin Akhter BANU et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Non-redundant functions of two proline dehydrogenase isoforms in Arabidopsis

(2010) Dietmar Funck et al.   BMC PLANT BIOLOGY

In planta function of compatible solute transporters of the AtProT family

(2010) Silke Lehmann et al.   JOURNAL OF EXPERIMENTAL BOTANY

Mechanisms independent of abscisic acid (ABA) or proline feedback have a predominant role in transcriptional regulation of proline metabolism during low water potential and stress recovery

(2010) SANDEEP SHARMA et al.   PLANT CELL AND ENVIRONMENT

Novel Regulators in Photosynthetic Redox Control of Plant Metabolism and Gene Expression

(2010) K.-J. Dietz et al.   PLANT PHYSIOLOGY

A Central Regulatory System Largely Controls Transcriptional Activation and Repression Responses to Phosphate Starvation in Arabidopsis

(2010) Regla Bustos et al.   PLoS Genetics

Oxidized low-density lipoproteins upregulate proline oxidase to initiate ROS-dependent autophagy

(2009) O. Zabirnyk et al.   CARCINOGENESIS

Unraveling Δ1-Pyrroline-5-Carboxylate-Proline Cycle in Plants by Uncoupled Expression of Proline Oxidation Enzymes

(2009) Gad Miller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation and function of proline oxidase under nutrient stress

(2009) Jui Pandhare et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Isoenzyme replacement of glucose-6-phosphate dehydrogenase in the cytosol improves stress tolerance in plants

(2009) J. Scharte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proline: a multifunctional amino acid

(2009) László Szabados et al.   TRENDS IN PLANT SCIENCE

Ornithine-δ-aminotransferase is essential for Arginine Catabolism but not for Proline Biosynthesis

(2008) Dietmar Funck et al.   BMC PLANT BIOLOGY

DuplicatedP5CSgenes of Arabidopsis play distinct roles in stress regulation and developmental control of proline biosynthesis

(2007) Gyöngyi Székely et al.   PLANT JOURNAL