Translocation of Proteins through a Distorted Lipid Bilayer

Structural basis for membrane insertion by the human ER membrane protein complex

(2020) Tino Pleiner et al.   SCIENCE

Structures of a P4-ATPase lipid flippase in lipid bilayers

(2020) Yilin He et al.   Protein & Cell

The architecture of EMC reveals a path for membrane protein insertion

(2020) John P O'Donnell et al.   eLife

Ubiquitin-mediated regulation of sterol homeostasis

(2020) Dick J.H. van den Boomen et al.   CURRENT OPINION IN CELL BIOLOGY

Structure of a nascent membrane protein as it folds on the BAM complex

(2020) David Tomasek et al.   NATURE

Structure of the ER membrane complex, a transmembrane-domain insertase

(2020) Lin Bai et al.   NATURE

Structural insight into mitochondrial β-barrel outer membrane protein biogenesis

(2020) Kathryn A. Diederichs et al.   Nature Communications

Doa10 is a membrane protein retrotranslocase in ER-associated protein degradation

(2020) Claudia C Schmidt et al.   eLife

Structural Basis of Tail-Anchored Membrane Protein Biogenesis by the GET Insertase Complex

(2020) Melanie A. McDowell et al.   MOLECULAR CELL

HRD Complex Self-Remodeling Enables a Novel Route of Membrane Protein Retrotranslocation

(2020) Sonya Neal et al.   iScience

Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients

(2020) Lakshmi E Miller-Vedam et al.   eLife

Distortion of the bilayer and dynamics of the BAM complex in lipid nanodiscs

(2020) Matthew G. Iadanza et al.   Communications Biology

Structural basis of Ca2+-dependent activation and lipid transport by a TMEM16 scramblase

(2019) Maria E Falzone et al.   eLife

Rhomboid distorts lipids to break the viscosity-imposed speed limit of membrane diffusion

(2019) Alex J. B. Kreutzberger et al.   SCIENCE

Protein translocation by the SecA ATPase occurs by a power‐stroke mechanism

(2019) Marco A Catipovic et al.   EMBO JOURNAL

Current Advances in Protein Import into Peroxisomes

(2019) Thomas Walter et al.   PROTEIN JOURNAL

Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM

(2019) Valeria Kalienkova et al.   eLife

Structure of the substrate-engaged SecA-SecY protein translocation machine

(2019) Chengying Ma et al.   Nature Communications

Cryo-EM Studies of TMEM16F Calcium-Activated Ion Channel Suggest Features Important for Lipid Scrambling

(2019) Shengjie Feng et al.   Cell Reports

Mechanistic insights into ER-associated protein degradation

(2018) Xudong Wu et al.   CURRENT OPINION IN CELL BIOLOGY

The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins

(2018) Sonya Neal et al.   MOLECULAR CELL

Membrane protein insertion through a mitochondrial β-barrel gate

(2018) Alexandra I. C. Höhr et al.   SCIENCE

The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins

(2018) Matthew J Shurtleff et al.   eLife

Structural investigation of glycan recognition by the ERAD quality control lectin Yos9

(2018) Andreas Kniss et al.   JOURNAL OF BIOMOLECULAR NMR

C-terminal kink formation is required for lateral gating in BamA

(2018) Karl Lundquist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EMC Is Required to Initiate Accurate Membrane Protein Topogenesis

(2018) Patrick J. Chitwood et al.   CELL

Evolution of protein transport to the chloroplast envelope membranes

(2018) Philip M. Day et al.   PHOTOSYNTHESIS RESEARCH

The ER membrane protein complex is a transmembrane domain insertase

(2017) Alina Guna et al.   SCIENCE

YidC Insertase of Escherichia coli : Water Accessibility and Membrane Shaping

(2017) Yuanyuan Chen et al.   STRUCTURE

Crystal structure of a substrate-engaged SecY protein-translocation channel

(2016) Long Li et al.   NATURE

The structure of the  -barrel assembly machinery complex

(2016) J. Bakelar et al.   SCIENCE

How Polyomaviruses Exploit the ERAD Machinery to Cause Infection

(2016) Allison Dupzyk et al.   Viruses-Basel

The yeast ERAD-C ubiquitin ligase Doa10 recognizes an intramembrane degron

(2015) Gregor Habeck et al.   JOURNAL OF CELL BIOLOGY

Pore-forming toxins: ancient, but never really out of fashion

(2015) Matteo Dal Peraro et al.   NATURE REVIEWS MICROBIOLOGY

Glycosylation-directed quality control of protein folding

(2015) Chengchao Xu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structure of the Sec61 channel opened by a signal sequence

(2015) R. M. Voorhees et al.   SCIENCE

The membrane insertase YidC

(2014) Ross E. Dalbey et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Structure of the Mammalian Ribosome-Sec61 Complex to 3.4 Å Resolution

(2014) Rebecca M. Voorhees et al.   CELL

A “Push and Slide” Mechanism Allows Sequence-Insensitive Translocation of Secretory Proteins by the SecA ATPase

(2014) Benedikt W. Bauer et al.   CELL

Protein quality control at the inner nuclear membrane

(2014) Anton Khmelinskii et al.   NATURE

Structural basis of Sec-independent membrane protein insertion by YidC

(2014) Kaoru Kumazaki et al.   NATURE

Quality control of inner nuclear membrane proteins by the Asi complex

(2014) O. Foresti et al.   SCIENCE

Der1 promotes movement of misfolded proteins through the endoplasmic reticulum membrane

(2013) Martin Mehnert et al.   NATURE CELL BIOLOGY

Structural model for the protein-translocating element of the twin-arginine transport system

(2013) F. Rodriguez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Glove-like Structure of the Conserved Membrane Protein TatC Provides Insight into Signal Sequence Recognition in Twin-Arginine Translocation

(2013) Sureshkumar Ramasamy et al.   STRUCTURE

The YidC/Oxa1/Alb3 protein family: common principles and distinct features

(2012) Manfred J. Saller et al.   BIOLOGICAL CHEMISTRY

Structure of the TatC core of the twin-arginine protein transport system

(2012) Sarah E. Rollauer et al.   NATURE

The twin-arginine translocation (Tat) protein export pathway

(2012) Tracy Palmer et al.   NATURE REVIEWS MICROBIOLOGY

Tail-anchored membrane protein insertion into the endoplasmic reticulum

(2011) Ramanujan S. Hegde et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant α-1 antitrypsin from the endoplasmic reticulum

(2011) Ethan J Greenblatt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Retrotranslocation of a Misfolded Luminal ER Protein by the Ubiquitin-Ligase Hrd1p

(2010) Pedro Carvalho et al.   CELL

Biogenesis of β-barrel membrane proteins in bacteria and eukaryotes: evolutionary conservation and divergence

(2009) Dirk M. Walther et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Usa1 Functions as a Scaffold of the HRD-Ubiquitin Ligase

(2009) Sabine C. Horn et al.   MOLECULAR CELL