Genetics of Intracranial Aneurysms

Exome sequencing in 38 patients with intracranial aneurysms and subarachnoid hemorrhage

(2020) Thomas Sauvigny et al.   JOURNAL OF NEUROLOGY

Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors

(2020) Mark K. Bakker et al.   NATURE GENETICS

Genomic Variations in Susceptibility to Intracranial Aneurysm in the Korean Population

(2019) Eun Hong et al.   Journal of Clinical Medicine

Novel Drug Targets for Ischemic Stroke Identified Through Mendelian Randomization Analysis of the Blood Proteome

(2019) Michael Chong et al.   CIRCULATION

Patient and aneurysm characteristics in familial intracranial aneurysms. A systematic review and meta-analysis

(2019) Emma M. H. Slot et al.   PLoS One

Familial Intracranial Aneurysm in Newfoundland: Clinical and Genetic Analysis

(2019) Amy E. Powell et al.   CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES

Exome sequencing reveals a novel variant in NFX1 causing intracranial aneurysm in a Chinese family

(2019) Xinghuan Ding et al.   Journal of NeuroInterventional Surgery

Epigenetic landscapes suggest that genetic risk for intracranial aneurysm operates on the endothelium

(2019) Kerry E. Poppenberg et al.   BMC Medical Genomics

Exome-chip association analysis of intracranial aneurysms

(2019) Femke N.G. van 't Hof et al.   NEUROLOGY

Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke

(2019) Gad Abraham et al.   Nature Communications

Are drug targets with genetic support twice as likely to be approved? Revised estimates of the impact of genetic support for drug mechanisms on the probability of drug approval

(2019) Emily A. King et al.   PLoS Genetics

Rare Coding Variants in ANGPTL6 Are Associated with Familial Forms of Intracranial Aneurysm

(2018) Romain Bourcier et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Increased Prevalence of Cerebrovascular Disease in Hospitalized Patients with Marfan Syndrome

(2018) Sarasa T. Kim et al.   Journal of Stroke & Cerebrovascular Diseases

Intracranial Aneurysm–Associated Single-Nucleotide Polymorphisms Alter Regulatory DNA in the Human Circle of Willis

(2018) Melanie D. Laarman et al.   STROKE

Genetics of Intracranial Aneurysms

(2018) Sirui Zhou et al.   STROKE

Genome-wide association analysis identifies new candidate risk loci for familial intracranial aneurysm in the French-Canadian population

(2018) Sirui Zhou et al.   Scientific Reports

Exome Sequencing Identifies LOXL2 Mutation as a Cause of Familial Intracranial Aneurysm

(2018) YaQiu Wu et al.   World Neurosurgery

Increased Prevalence of Cerebrovascular Disease in Hospitalized Patients with Marfan Syndrome

(2018) Sarasa T. Kim et al.   Journal of Stroke & Cerebrovascular Diseases

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

(2018) Amit V. Khera et al.   NATURE GENETICS

PCNT point mutations and familial intracranial aneurysms

(2018) Oswaldo Lorenzo-Betancor et al.   NEUROLOGY

Genetic variants associated with type 2 diabetes and adiposity and risk of intracranial and abdominal aortic aneurysms

(2017) Femke NG van 't Hof et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Increased Prevalence of Cerebrovascular Disease in Hospitalized Patients with Ehlers–Danlos Syndrome

(2017) Sarasa T. Kim et al.   Journal of Stroke & Cerebrovascular Diseases

Polycystic kidney disease among 4,436 intracranial aneurysm patients from a defined population

(2017) Heidi J. Nurmonen et al.   NEUROLOGY

Increased Prevalence of Cerebrovascular Disease in Hospitalized Patients with Ehlers–Danlos Syndrome

(2017) Sarasa T. Kim et al.   Journal of Stroke & Cerebrovascular Diseases

RNF213 Is Associated with Intracranial Aneurysms in the French-Canadian Population

(2016) Sirui Zhou et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Prevalence of Intracranial Aneurysms in Patients with Connective Tissue Diseases: A Retrospective Study

(2016) S. T. Kim et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

THSD1preserves vascular integrity and protects against intraplaque haemorrhaging in ApoE−/−mice

(2016) Remco A. Haasdijk et al.   CARDIOVASCULAR RESEARCH

Surgical outcomes of Majewski osteodysplastic primordial dwarfism Type II with intracranial vascular anomalies

(2016) Mario Teo et al.   Journal of Neurosurgery-Pediatrics

A missense variant in FGD6 confers increased risk of polypoidal choroidal vasculopathy

(2016) Lulin Huang et al.   NATURE GENETICS

THSD1 (Thrombospondin Type 1 Domain Containing Protein 1) Mutation in the Pathogenesis of Intracranial Aneurysm and Subarachnoid Hemorrhage

(2016) Teresa Santiago-Sim et al.   STROKE

Deficiency of Endothelium-Specific Transcription Factor Sox17 Induces Intracranial Aneurysm

(2015) S. Lee et al.   CIRCULATION

p130Cas/BCAR1 scaffold protein in tissue homeostasis and pathogenesis

(2015) Maria del Pilar Camacho Leal et al.   GENE

Exome sequencing in seven families and gene-based association studies indicate genetic heterogeneity and suggest possible candidates for fibromuscular dysplasia

(2015) Soto Romuald Kiando et al.   JOURNAL OF HYPERTENSION

Genetic Determinants of Unruptured Intracranial Aneurysms in the General Population

(2015) Abbas Peymani et al.   STROKE

Genetic Study of Intracranial Aneurysms

(2015) Junxia Yan et al.   STROKE

Lessons Learned from Whole Exome Sequencing in Multiplex Families Affected by a Complex Genetic Disorder, Intracranial Aneurysm

(2015) Janice L. Farlow et al.   PLoS One

Genetic Variants Underlying Risk of Intracranial Aneurysms: Insights from a GWAS in Portugal

(2015) Patrícia Abrantes et al.   PLoS One

Genetic risk load according to the site of intracranial aneurysms

(2014) F. N. G. van 't Hof et al.   NEUROLOGY

Genome-Wide Association Study of Intracranial Aneurysm Identifies a New Association on Chromosome 7

(2014) Tatiana Foroud et al.   STROKE

High Risk Population Isolate Reveals Low Frequency Variants Predisposing to Intracranial Aneurysms

(2014) Mitja I. Kurki et al.   PLoS Genetics

Epidemiology and genetics of intracranial aneurysms

(2013) F. Caranci et al.   EUROPEAN JOURNAL OF RADIOLOGY

Genetic risk factors for intracranial aneurysms: A meta-analysis in more than 116,000 individuals

(2013) V. S. Alg et al.   NEUROLOGY

The Association Between Genetic Risk Factors and the Size of Intracranial Aneurysms at Time of Rupture

(2013) Rachel Kleinloog et al.   NEUROSURGERY

Screening for Cerebrovascular Disease in Microcephalic Osteodysplastic Primordial Dwarfism Type II (MOPD II): An Evidence-Based Proposal

(2013) Luke D. Perry et al.   PEDIATRIC NEUROLOGY

Whole Exome Sequencing of Intracranial Aneurysm

(2013) T. Foroud et al.   STROKE

Genetic Variant RNF213 c.14576G>A in Various Phenotypes of Intracranial Major Artery Stenosis/Occlusion

(2013) Satoru Miyawaki et al.   STROKE

Independent Risk Factors for Intracranial Aneurysms and Their Joint Effect

(2013) Monique H.M. Vlak et al.   STROKE

Genome-wide association study for intracranial aneurysm in the Japanese population identifies three candidate susceptible loci and a functional genetic variant at EDNRA

(2012) Siew-Kee Low et al.   HUMAN MOLECULAR GENETICS

Genome-Wide Association Study of Intracranial Aneurysms Confirms Role of Anril and SOX17 in Disease Risk

(2012) Tatiana Foroud et al.   STROKE

Prevalence of unruptured intracranial aneurysms, with emphasis on sex, age, comorbidity, country, and time period: a systematic review and meta-analysis

(2011) Monique HM Vlak et al.   LANCET NEUROLOGY

Common variant near the endothelin receptor type A (EDNRA) gene is associated with intracranial aneurysm risk

(2011) K. Yasuno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Majewski Osteodysplastic Primordial Dwarfism Type II (MOPD II): Expanding the vascular phenotype

(2010) Michael B. Bober et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

A genome-wide association study identifies RNF213 as the first Moyamoya disease gene

(2010) Fumiaki Kamada et al.   JOURNAL OF HUMAN GENETICS

Genome-wide association analysis of copy number variations in subarachnoid aneurysmal hemorrhage

(2010) Joon Seol Bae et al.   JOURNAL OF HUMAN GENETICS

Genome-wide association study to identify genetic variants present in Japanese patients harboring intracranial aneurysms

(2010) Koichi Akiyama et al.   JOURNAL OF HUMAN GENETICS

Genome-wide association study of intracranial aneurysm identifies three new risk loci

(2010) Katsuhito Yasuno et al.   NATURE GENETICS

Optimal screening strategy for familial intracranial aneurysms: A cost-effectiveness analysis

(2010) A. S. E. Bor et al.   NEUROLOGY

Genetic Epidemiology of Spontaneous Subarachnoid Hemorrhage

(2010) Miikka Korja et al.   STROKE

Autosomal dominant polycystic kidney disease: the last 3 years

(2009) Vicente E. Torres et al.   KIDNEY INTERNATIONAL

Changes in case fatality of aneurysmal subarachnoid haemorrhage over time, according to age, sex, and region: a meta-analysis

(2009) Dennis J Nieuwkamp et al.   LANCET NEUROLOGY

Risk of subarachnoid haemorrhage according to number of affected relatives: a population based case–control study

(2008) A. S. E. Bor et al.   BRAIN

Screening for brain aneurysm in the Familial Intracranial Aneurysm study: frequency and predictors of lesion detection

(2008) Robert D. Brown et al.   JOURNAL OF NEUROSURGERY

Susceptibility loci for intracranial aneurysm in European and Japanese populations

(2008) Kaya Bilguvar et al.   NATURE GENETICS