Delivery of siHIF‐1α to Reconstruct Tumor Normoxic Microenvironment for Effective Chemotherapeutic and Photodynamic Anticancer Treatments

Integration of Indocyanine Green Analogs as Near‐Infrared Fluorescent Carrier for Precise Imaging‐Guided Gene Delivery

(2020) Hong Liang et al.   Small

Natural products remodel cancer-associated fibroblasts in desmoplastic tumors

(2020) Rujing Chen et al.   Acta Pharmaceutica Sinica B

Magnetofection: Magic magnetic nanoparticles for efficient gene delivery

(2020) Qunjie Bi et al.   CHINESE CHEMICAL LETTERS

Normalizing Function of Tumor Vessels: Progress, Opportunities, and Challenges

(2019) John D. Martin et al.   Annual Review of Physiology

Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy

(2019) Vikash P. Chauhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improving cancer therapy through the nanomaterials-assisted alleviation of hypoxia

(2019) Abhishek Sahu et al.   BIOMATERIALS

Delivery of small interfering RNA against Nogo-B receptor via tumor-acidity responsive nanoparticles for tumor vessel normalization and metastasis suppression

(2018) Bin Wang et al.   BIOMATERIALS

Of Thiols and Disulfides: Methods for Chemoselective Formation of Asymmetric Disulfides in Synthetic Peptides and Polymers

(2018) Olga Schäfer et al.   CHEMISTRY-A EUROPEAN JOURNAL

The hypoxic tumour microenvironment

(2018) Varvara Petrova et al.   Oncogenesis

Hypoxic tumor therapy by hemoglobin-mediated drug delivery and reversal of hypoxia-induced chemoresistance

(2018) Jie Yang et al.   BIOMATERIALS

Tumor immunoevasion via acidosis-dependent induction of regulatory tumor-associated macrophages

(2018) Toszka Bohn et al.   NATURE IMMUNOLOGY

Disulfide modified self-assembly of lipopeptides with arginine-rich periphery achieve excellent gene transfection efficiency at relatively low nitrogen to phosphorus ratios

(2017) Xiaobing Chen et al.   Journal of Materials Chemistry B

Selectively Sensitizing Malignant Cells to Photothermal Therapy Using a CD44-Targeting Heat Shock Protein 72 Depletion Nanosystem

(2016) Shouju Wang et al.   ACS Nano

Tumor priming using metronomic chemotherapy with neovasculature-targeted, nanoparticulate paclitaxel

(2016) Xin Luan et al.   BIOMATERIALS

Hypoxic tumor microenvironment: Opportunities to develop targeted therapies

(2016) Akhil Patel et al.   BIOTECHNOLOGY ADVANCES

Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy

(2016) Zijian Zhou et al.   CHEMICAL SOCIETY REVIEWS

Antiangiogenic therapy in oncology: current status and future directions

(2016) Gordon C Jayson et al.   LANCET

Specially-Made Lipid-Based Assemblies for Improving Transmembrane Gene Delivery: Comparison of Basic Amino Acid Residue Rich Periphery

(2016) Qian Jiang et al.   MOLECULAR PHARMACEUTICS

The ever-expanding role of HIF in tumour and stromal biology

(2016) Edward L. LaGory et al.   NATURE CELL BIOLOGY

Reduction Responsive Self-Assembled Nanoparticles Based on Disulfide-Linked Drug–Drug Conjugate with High Drug Loading and Antitumor Efficacy

(2015) Qin Song et al.   MOLECULAR PHARMACEUTICS

Virus-inspired mimics: self-assembly of dendritic lipopeptides into arginine-rich nanovectors for improving gene delivery

(2015) Xianghui Xu et al.   Journal of Materials Chemistry B

HIF-1α pathway: role, regulation and intervention for cancer therapy

(2015) Georgina N. Masoud et al.   Acta Pharmaceutica Sinica B

A chitosan-graft-PEI-candesartan conjugate for targeted co-delivery of drug and gene in anti-angiogenesis cancer therapy

(2014) Xiuli Bao et al.   BIOMATERIALS

Antiangiogenesis Strategies Revisited: From Starving Tumors to Alleviating Hypoxia

(2014) Rakesh K. Jain   CANCER CELL

Hyaluronic acid based self-assembling nanosystems for CD44 target mediated siRNA delivery to solid tumors

(2013) Shanthi Ganesh et al.   BIOMATERIALS

p53 mediated apoptosis by reduction sensitive shielding ternary complexes based on disulfide linked PEI ternary complexes

(2013) Yiyan He et al.   BIOMATERIALS

Strategies for advancing cancer nanomedicine

(2013) Vikash P. Chauhan et al.   NATURE MATERIALS

Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels

(2013) Vikash P. Chauhan et al.   Nature Communications

Polyethyleneimine/DNA polyplexes with reduction-sensitive hyaluronic acid derivatives shielding for targeted gene delivery

(2012) Yiyan He et al.   BIOMATERIALS

Recent agents targeting HIF-1α for cancer therapy

(2012) Yaozhong Hu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Therapeutic Delivery of siRNA Silencing HIF-1 Alpha with Micellar Nanoparticles Inhibits Hypoxic Tumor Growth

(2012) Xi-Qiu Liu et al.   MOLECULAR PHARMACEUTICS

Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future perspectives

(2011) Yiyun Cheng et al.   CHEMICAL SOCIETY REVIEWS

Tumor angiogenesis: molecular pathways and therapeutic targets

(2011) Sara M Weis et al.   NATURE MEDICINE

The HIF-1-active microenvironment: An environmental target for cancer therapy

(2009) Shinae Kizaka-Kondoh et al.   ADVANCED DRUG DELIVERY REVIEWS

Hypoxia-inducible factor in cancer angiogenesis: Structure, regulation and clinical perspectives

(2009) Zaher K. Otrock et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Target Specific Intracellular Delivery of siRNA/PEI−HA Complex by Receptor Mediated Endocytosis

(2009) Ge Jiang et al.   MOLECULAR PHARMACEUTICS

HIF1α Induces the Recruitment of Bone Marrow-Derived Vascular Modulatory Cells to Regulate Tumor Angiogenesis and Invasion

(2008) Rose Du et al.   CANCER CELL