A Targeted Nanosystem for Detection of Inflammatory Diseases via Fluorescent/Optoacoustic Imaging and Therapy via Modulating Nrf2/NF‐κB Pathways

Location, location, location: how the tissue microenvironment affects inflammation in RA

(2021) Christopher D. Buckley et al.   Nature Reviews Rheumatology

Controlled Synthesis and Surface Engineering of Janus Chitosan‐Gold Nanoparticles for Photoacoustic Imaging‐Guided Synergistic Gene/Photothermal Therapy

(2021) Xiaoguang Dai et al.   Small

Engineering Oxaliplatin Prodrug Nanoparticles for Second Near‐Infrared Fluorescence Imaging‐Guided Immunotherapy of Colorectal Cancer

(2021) Qiurong Zhu et al.   Small

Activatable Molecular Probes for Second Near-Infrared Fluorescence, Chemiluminescence, and Photoacoustic Imaging

(2020) Kanyi Pu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NRF2 as a Therapeutic Target in Neurodegenerative Diseases

(2020) Mikah S. Brandes et al.   ASN Neuro

Organ-specific metabolic profiles of the liver and kidney during brain death and afterwards during normothermic machine perfusion of the kidney

(2020) Anne C. van Erp et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

(2020) Helmut Sies et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines

(2020) Cheng Gao et al.   Nature Communications

Triamcinolone-Gold Nanoparticles Repolarize Synoviocytes and Macrophages in Inflamed Synovium

(2020) Jun-Young Park et al.   ACS Applied Materials & Interfaces

Biomimetic carbon monoxide nanogenerator ameliorates streptozotocin induced type 1 diabetes in mice

(2020) Cheng Zhang et al.   BIOMATERIALS

A self-driven bioinspired nanovehicle by leukocyte membrane-hitchhiking for early detection and treatment of atherosclerosis

(2020) Guanghao Wu et al.   BIOMATERIALS

Coating of a Novel Antimicrobial Nanoparticle with a Macrophage Membrane for the Selective Entry into Infected Macrophages and Killing of Intracellular Staphylococci

(2020) Yuanfeng Li et al.   ADVANCED FUNCTIONAL MATERIALS

Interplay of cardiovascular mediators, oxidative stress and inflammation in liver disease and its complications

(2020) Csaba Matyas et al.   Nature Reviews Cardiology

An Activatable Nano‐Prodrug for Treating Tyrosine‐Kinase‐Inhibitor‐Resistant Non‐Small Cell Lung Cancer and for Optoacoustic and Fluorescent Imaging

(2020) Xin Xie et al.   Small

Efficient Polysulfide‐Based Nanotheranostics for Triple‐Negative Breast Cancer: Ratiometric Photoacoustics Monitored Tumor Microenvironment‐Initiated H 2 S Therapy

(2020) Jie Li et al.   Small

Ulcerative colitis

(2020) Taku Kobayashi et al.   Nature Reviews Disease Primers

Acute kidney injury pathology and pathophysiology: a retrospective review

(2020) Joseph P Gaut et al.   Clinical Kidney Journal

A dopamine-precursor-based nanoprodrug for in-situ drug release and treatment of acute liver failure by inhibiting NLRP3 inflammasome and facilitating liver regeneration

(2020) Chenyue Zhan et al.   BIOMATERIALS

A Nanoprobe for Diagnosing and Mapping Lymphatic Metastasis of Tumor Using 3D Multispectral Optoacoustic Tomography Owing to Aggregation/Deaggregation Induced Spectral Change

(2019) Yinglong Wu et al.   ADVANCED FUNCTIONAL MATERIALS

Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases

(2019) Antonio Cuadrado et al.   NATURE REVIEWS DRUG DISCOVERY

Molecular optical imaging probes for early diagnosis of drug-induced acute kidney injury

(2019) Jiaguo Huang et al.   NATURE MATERIALS

Engineering Cell Membrane‐Based Nanotherapeutics to Target Inflammation

(2019) Huize Yan et al.   Advanced Science

An Organic Afterglow Protheranostic Nanoassembly

(2019) Shasha He et al.   ADVANCED MATERIALS

A Gold Nanocage/Cluster Hybrid Structure for Whole-Body Multispectral Optoacoustic Tomography Imaging, EGFR Inhibitor Delivery, and Photothermal Therapy

(2019) Chenyue Zhan et al.   Small

A Red Emissive Two‐Photon Fluorescence Probe Based on Carbon Dots for Intracellular pH Detection

(2019) Xiaoxue Ye et al.   Small

Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes

(2019) Karl E. Carlström et al.   Nature Communications

Nanoaggregate Probe for Breast Cancer Metastasis through Multispectral Optoacoustic Tomography and Aggregation-Induced NIR-I/II Fluorescence Imaging

(2019) Juan Ouyang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rapid and Large-Scale Production of Multi-Fluorescence Carbon Dots by a Magnetic Hyperthermia Method

(2019) Zhijie Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Propofol attenuates inflammatory response and apoptosis to protect d-galactosamine/lipopolysaccharide induced acute liver injury via regulating TLR4/NF-κB/NLRP3 pathway

(2019) Zhaojian Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Dl-3-n-Butylphthalide Inhibits NLRP3 Inflammasome and Mitigates Alzheimer's-Like Pathology via Nrf2-TXNIP-TrX Axis

(2018) Chun-Yan Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Nrf2 as a therapeutic target for rheumatic diseases

(2018) María Luisa Ferrándiz et al.   BIOCHEMICAL PHARMACOLOGY

Thalidomide potentiates etoposide-induced apoptosis in murine neuroblastoma through suppression of NF-κB activation

(2018) Tomomasa Hiramatsu et al.   PEDIATRIC SURGERY INTERNATIONAL

Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach

(2018) Antonio Cuadrado et al.   PHARMACOLOGICAL REVIEWS

HEPATOKIN1 is a biochemistry-based model of liver metabolism for applications in medicine and pharmacology

(2018) Nikolaus Berndt et al.   Nature Communications

WST11 Vascular Targeted Photodynamic Therapy Effect Monitoring by Multispectral Optoacoustic Tomography (MSOT) in Mice

(2018) Volker Neuschmelting et al.   Theranostics

Neutrophil membrane-coated nanoparticles inhibit synovial inflammation and alleviate joint damage in inflammatory arthritis

(2018) Qiangzhe Zhang et al.   Nature Nanotechnology

Photoacoustic and Magnetic Resonance Imaging Bimodal Contrast Agent Displaying Amplified Photoacoustic Signal

(2018) Yukun Duan et al.   Small

Activatable probes for diagnosing and positioning liver injury and metastatic tumors by multispectral optoacoustic tomography

(2018) Yinglong Wu et al.   Nature Communications

Pretreated Macrophage-Membrane-Coated Gold Nanocages for Precise Drug Delivery for Treatment of Bacterial Infections

(2018) Can Wang et al.   ADVANCED MATERIALS

Liver inflammation and fibrosis

(2017) Yukinori Koyama et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammation, metaflammation and immunometabolic disorders

(2017) Gökhan S. Hotamisligil   NATURE

Liposomes Coated with Isolated Macrophage Membrane Can Target Lung Metastasis of Breast Cancer

(2016) Haiqiang Cao et al.   ACS Nano

Suppression of Hepatic Inflammation via Systemic siRNA Delivery by Membrane-Disruptive and Endosomolytic Helical Polypeptide Hybrid Nanoparticles

(2016) Hua He et al.   ACS Nano

Diketopyrrolopyrrole-Based Ratiometric/Turn-on Fluorescent Chemosensors for Citrate Detection in the Near-Infrared Region by an Aggregation-Induced Emission Mechanism

(2016) Yandi Hang et al.   ANALYTICAL CHEMISTRY

Biointerfacing and Applications of Cell Membrane-Coated Nanoparticles

(2016) Ashley V. Kroll et al.   BIOCONJUGATE CHEMISTRY

Hepatic sinusoids in liver injury, inflammation, and fibrosis: new pathophysiological insights

(2016) Thomas Greuter et al.   JOURNAL OF GASTROENTEROLOGY

Acute liver injury and acute liver failure from mushroom poisoning in North America

(2016) Constantine J. Karvellas et al.   LIVER INTERNATIONAL

Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways

(2015) Joanna D. Wardyn et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Fisetin Imparts Neuroprotection in Experimental Diabetic Neuropathy by Modulating Nrf2 and NF-κB Pathways

(2015) Reddemma Sandireddy et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Chitosan/siRNA Nanoparticles Targeting Cyclooxygenase Type 2 Attenuate Unilateral Ureteral Obstruction-induced Kidney Injury in Mice

(2015) Chuanxu Yang et al.   Theranostics

Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases

(2014) Asima Bhattacharyya et al.   PHYSIOLOGICAL REVIEWS

Biological Relevance of Inflammation and Oxidative Stress in the Pathogenesis of Arterial Diseases

(2013) David P. Hajjar et al.   AMERICAN JOURNAL OF PATHOLOGY

Asthma

(2013) Fernando D Martinez et al.   LANCET

Acute Liver Failure

(2013) William Bernal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Anti-Inflammatory Therapy in Chronic Disease: Challenges and Opportunities

(2013) I. Tabas et al.   SCIENCE

Toward clinical application of the Keap1–Nrf2 pathway

(2013) Takafumi Suzuki et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Fumarate Is Cardioprotective via Activation of the Nrf2 Antioxidant Pathway

(2012) Houman Ashrafian et al.   Cell Metabolism

Nrf2 Activators as Attractive Therapeutics for Diabetic Nephropathy: FIG. 1.

(2011) Judy B. de Haan   DIABETES

Volumetric real-time multispectral optoacoustic tomography of biomarkers

(2011) Daniel Razansky et al.   Nature Protocols

Molecular Imaging by Means of Multispectral Optoacoustic Tomography (MSOT)

(2010) Vasilis Ntziachristos et al.   CHEMICAL REVIEWS

Inflammation

(2008) Ursula Weiss   NATURE