CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma

Cancer statistics, 2015

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Subtyping Pancreatic Cancer

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European cancer mortality predictions for the year 2014

(2014) M. Malvezzi et al.   ANNALS OF ONCOLOGY

Identifying molecular subtypes related to clinicopathologic factors in pancreatic cancer

(2014) Shinuk Kim et al.   Biomedical Engineering Online

Src Inhibition Is Still a Relevant Target in Pancreatic Cancer

(2014) T. J. George et al.   ONCOLOGIST

Removing batch effects for prediction problems with frozen surrogate variable analysis

(2014) Hilary S. Parker et al.   PeerJ

High SIRT1 expression is a negative prognosticator in pancreatic ductal adenocarcinoma

(2013) Albrecht Stenzinger et al.   BMC CANCER

Recent progress in pancreatic cancer

(2013) Christopher L. Wolfgang et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Pregnane X Receptor (PXR) at the Crossroads of Human Metabolism and Disease

(2013) Ioannis Koutsounas et al.   CURRENT DRUG METABOLISM

3D structures and ligand specificities of nuclear xenobiotic receptors CAR, PXR and VDR

(2013) Baojian Wu et al.   DRUG DISCOVERY TODAY

Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine

(2013) Daniel D. Von Hoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evolution and dynamics of pancreatic cancer progression

(2013) S Yachida et al.   ONCOGENE

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

(2012) Jeffrey T. Leek et al.   BIOINFORMATICS

A phase 1 study of gemcitabine combined with dasatinib in patients with advanced solid tumors

(2012) David S. Hong et al.   INVESTIGATIONAL NEW DRUGS

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

(2012) Andrew V. Biankin et al.   NATURE

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Pancreatic cancer

(2011) Audrey Vincent et al.   LANCET

Irinotecan induces steroid and xenobiotic receptor (SXR) signaling to detoxification pathway in colon cancer cells

(2011) Agnes Basseville et al.   Molecular Cancer

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

(2011) Eric A Collisson et al.   NATURE MEDICINE

FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer

(2011) Thierry Conroy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Profiling the expression of cytochrome P450 in breast cancer

(2010) Graeme I Murray et al.   HISTOPATHOLOGY

Towards a knowledge-based Human Protein Atlas

(2010) Mathias Uhlen et al.   NATURE BIOTECHNOLOGY

Pancreatic Cancer

(2010) Manuel Hidalgo   NEW ENGLAND JOURNAL OF MEDICINE

Expressions of Cytochrome P450, UDP-Glucuronosyltranferase, and Transporter Genes in Monolayer Carcinoma Cells Change in Subcutaneous Tumors Grown As Xenografts in Immunodeficient Nude Mice

(2009) M. Sugawara et al.   DRUG METABOLISM AND DISPOSITION

Factors underlying sensitivity of cancers to small-molecule kinase inhibitors

(2009) Pasi A. Jänne et al.   NATURE REVIEWS DRUG DISCOVERY

Identification of an Endogenous Ligand Bound to a Native Orphan Nuclear Receptor

(2009) Xiaohui Yuan et al.   PLoS One

Xenobiotic-Induced Transcriptional Regulation of Xenobiotic Metabolizing Enzymes of the Cytochrome P450 Superfamily in Human Extrahepatic Tissues

(2008) Petr Pavek et al.   CURRENT DRUG METABOLISM

Identification of the Human Enzymes Involved in the Oxidative Metabolism of Dasatinib: An Effective Approach for Determining Metabolite Formation Kinetics

(2008) L. Wang et al.   DRUG METABOLISM AND DISPOSITION

Metabolism and Disposition of Dasatinib after Oral Administration to Humans

(2008) L. J. Christopher et al.   DRUG METABOLISM AND DISPOSITION

Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity

(2008) L. Vermeulen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE