Protective antibodies elicited by SARS-CoV-2 spike protein vaccination are boosted in the lung after challenge in nonhuman primates
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Title
Protective antibodies elicited by SARS-CoV-2 spike protein vaccination are boosted in the lung after challenge in nonhuman primates
Authors
Keywords
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Journal
Science Translational Medicine
Volume 13, Issue 607, Pages eabi4547
Publisher
American Association for the Advancement of Science (AAAS)
Online
2021-07-27
DOI
10.1126/scitranslmed.abi4547
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Note: Only part of the references are listed.- Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection
- (2021) Emma S. Winkler et al. CELL
- Safety and immunogenicity of S-Trimer (SCB-2019), a protein subunit vaccine candidate for COVID-19 in healthy adults: a phase 1, randomised, double-blind, placebo-controlled trial
- (2021) Peter Richmond et al. LANCET
- BNT162b vaccines protect rhesus macaques from SARS-CoV-2
- (2021) Annette B. Vogel et al. NATURE
- SARS-CoV-2 vaccines strategies: a comprehensive review of phase 3 candidates
- (2021) Nikolaos C. Kyriakidis et al. npj Vaccines
- Safety and immunogenicity of SARS-CoV-2 recombinant protein vaccine formulations in healthy adults: interim results of a randomised, placebo-controlled, phase 1–2, dose-ranging study
- (2021) Paul A Goepfert et al. LANCET INFECTIOUS DISEASES
- The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates
- (2021) Bryan E. Jones et al. Science Translational Medicine
- An interactive web-based dashboard to track COVID-19 in real time
- (2020) Ensheng Dong et al. LANCET INFECTIOUS DISEASES
- Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
- (2020) Daniel Wrapp et al. SCIENCE
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- An Infectious cDNA Clone of SARS-CoV-2
- (2020) Xuping Xie et al. Cell Host & Microbe
- Development of an inactivated vaccine candidate for SARS-CoV-2
- (2020) Qiang Gao et al. SCIENCE
- DNA vaccine protection against SARS-CoV-2 in rhesus macaques
- (2020) Jingyou Yu et al. SCIENCE
- Development of an Inactivated Vaccine Candidate, BBIBP-CorV, with Potent Protection against SARS-CoV-2
- (2020) Hui Wang et al. CELL
- Distinct Early Serological Signatures Track with SARS-CoV-2 Survival
- (2020) Caroline Atyeo et al. IMMUNITY
- Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques
- (2020) Noe B. Mercado et al. NATURE
- ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques
- (2020) Neeltje van Doremalen et al. NATURE
- Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike
- (2020) Lihong Liu et al. NATURE
- Potently neutralizing and protective human antibodies against SARS-CoV-2
- (2020) Seth J. Zost et al. NATURE
- Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates
- (2020) Kizzmekia S. Corbett et al. NEW ENGLAND JOURNAL OF MEDICINE
- An mRNA Vaccine against SARS-CoV-2 — Preliminary Report
- (2020) Lisa A. Jackson et al. NEW ENGLAND JOURNAL OF MEDICINE
- Adjuvanted H5N1 influenza vaccine enhances both cross-reactive memory B cell and strain-specific naive B cell responses in humans
- (2020) Ali H. Ellebedy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2
- (2020) Xiangyang Chi et al. SCIENCE
- Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model
- (2020) Thomas F. Rogers et al. SCIENCE
- Safety and immunogenicity of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine in two formulations: two open, non-randomised phase 1/2 studies from Russia
- (2020) Denis Y Logunov et al. LANCET
- Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates
- (2020) Edward E. Walsh et al. NEW ENGLAND JOURNAL OF MEDICINE
- Phase 1–2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine
- (2020) Cheryl Keech et al. NEW ENGLAND JOURNAL OF MEDICINE
- REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters
- (2020) Alina Baum et al. SCIENCE
- Prospects for a safe COVID-19 vaccine
- (2020) Barton F. Haynes et al. Science Translational Medicine
- NVX-CoV2373 vaccine protects cynomolgus macaque upper and lower airways against SARS-CoV-2 challenge
- (2020) Mimi Guebre-Xabier et al. VACCINE
- A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes
- (2020) Tal Noy-Porat et al. Nature Communications
- Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes
- (2020) Tongqing Zhou et al. Cell Reports
- Respiratory Syncytial Virus F Subunit Vaccine With AS02 Adjuvant Elicits Balanced, Robust Humoral and Cellular Immunity in BALB/c Mice
- (2020) Yu Zheng et al. Frontiers in Immunology
- Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
- (2020) Merryn Voysey et al. LANCET
- Correlates of protection against SARS-CoV-2 in rhesus macaques
- (2020) Katherine McMahan et al. NATURE
- Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
- (2020) Fernando P. Polack et al. NEW ENGLAND JOURNAL OF MEDICINE
- IgA dominates the early neutralizing antibody response to SARS-CoV-2
- (2020) Delphine Sterlin et al. Science Translational Medicine
- Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 18–59 years: a randomised, double-blind, placebo-controlled, phase 1/2 clinical trial
- (2020) Yanjun Zhang et al. LANCET INFECTIOUS DISEASES
- OMIP-052: An 18-Color Panel for Measuring Th1, Th2, Th17, and Tfh Responses in Rhesus Macaques
- (2019) Mitzi M. Donaldson et al. CYTOMETRY PART A
- A versatile high throughput assay to characterize antibody-mediated neutrophil phagocytosis
- (2019) Christina B. Karsten et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Safety of AS03-adjuvanted influenza vaccines: A review of the evidence
- (2019) Catherine Cohet et al. VACCINE
- A high-throughput, bead-based, antigen-specific assay to assess the ability of antibodies to induce complement activation
- (2019) Stephanie Fischinger et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Adenovectors encoding RSV-F protein induce durable and mucosal immunity in macaques after two intramuscular administrations
- (2019) N. C. Salisch et al. npj Vaccines
- AS03-adjuvanted H5N1 vaccine promotes antibody diversity and affinity maturation, NAI titers, cross-clade H5N1 neutralization, but not H1N1 cross-subtype neutralization
- (2018) Surender Khurana et al. npj Vaccines
- Publisher Correction: Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis
- (2018) Robert N. Kirchdoerfer et al. Scientific Reports
- Viridot: An automated virus plaque (immunofocus) counter for the measurement of serological neutralizing responses with application to dengue virus
- (2018) Leah C. Katzelnick et al. PLoS Neglected Tropical Diseases
- Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion
- (2017) Alexandra C. Walls et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen
- (2017) Jesper Pallesen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Functional Role for Antibodies in Tuberculosis
- (2016) Lenette L. Lu et al. CELL
- Impact of adjuvants on CD4 + T cell and B cell responses to a protein antigen vaccine: Results from a phase II, randomized, multicenter trial
- (2016) Geert Leroux-Roels et al. CLINICAL IMMUNOLOGY
- A simple tube adapter to expedite and automate thawing of viably frozen cells
- (2016) Margaret Beddall et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Immunogenicity and Safety of an AS03-Adjuvanted H7N9 Pandemic Influenza Vaccine in a Randomized Trial in Healthy Adults
- (2016) Anuradha Madan et al. JOURNAL OF INFECTIOUS DISEASES
- Efficacy, safety, and immunogenicity of the human papillomavirus 16/18 AS04-adjuvanted vaccine in women older than 25 years: 7-year follow-up of the phase 3, double-blind, randomised controlled VIVIANE study
- (2016) Cosette M Wheeler et al. LANCET INFECTIOUS DISEASES
- Efficacy of the Herpes Zoster Subunit Vaccine in Adults 70 Years of Age or Older
- (2016) Anthony L. Cunningham et al. NEW ENGLAND JOURNAL OF MEDICINE
- Structure, Function, and Evolution of Coronavirus Spike Proteins
- (2016) Fang Li Annual Review of Virology
- A chimeric haemagglutinin-based influenza split virion vaccine adjuvanted with AS03 induces protective stalk-reactive antibodies in mice
- (2016) Raffael Nachbagauer et al. npj Vaccines
- Persistence of Antibody to Influenza A/H5N1 Vaccine Virus: Impact of AS03 Adjuvant
- (2015) Wilbur H. Chen et al. Clinical and Vaccine Immunology
- Evaluation of candidate vaccine approaches for MERS-CoV
- (2015) Lingshu Wang et al. Nature Communications
- AS03-Adjuvanted, Very-Low-Dose Influenza Vaccines Induce Distinctive Immune Responses Compared to Unadjuvanted High-Dose Vaccines in BALB/c Mice
- (2015) Karen K. Yam et al. Frontiers in Immunology
- Production and stabilization of the trimeric influenza hemagglutinin stem domain for potentially broadly protective influenza vaccines
- (2013) Y. Lu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Development and evaluation of AS03, an Adjuvant System containing α-tocopherol and squalene in an oil-in-water emulsion
- (2012) Nathalie Garçon et al. Expert Review of Vaccines
- Differential localization and function of antibody-forming cells responsive to inactivated or live-attenuated influenza virus vaccines
- (2012) Robert Sealy et al. INTERNATIONAL IMMUNOLOGY
- High-throughput, multiplexed IgG subclassing of antigen-specific antibodies from clinical samples
- (2012) Eric P. Brown et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Immunization with SARS Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS Virus
- (2012) Chien-Te Tseng et al. PLoS One
- Long-Term Antibody and Immune Memory Response Induced by Pulmonary Delivery of the Influenza Iscomatrix Vaccine
- (2011) Ana Vujanic et al. Clinical and Vaccine Immunology
- Effects of Different Adjuvants in the Context of Intramuscular and Intranasal Routes on Humoral and Cellular Immune Responses Induced by Detergent-Split A/H3N2 Influenza Vaccines in Mice
- (2011) Mariana Baz et al. Clinical and Vaccine Immunology
- Vaccine Adjuvants: Putting Innate Immunity to Work
- (2010) Robert L. Coffman et al. IMMUNITY
- H5N1 Influenza Vaccine Formulated with AS03A Induces Strong Cross-Reactive and Polyfunctional CD4 T-Cell Responses
- (2010) Philippe Moris et al. JOURNAL OF CLINICAL IMMUNOLOGY
- A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples
- (2010) Margaret E. Ackerman et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Hepatitis B vaccination: The key towards elimination and eradication of hepatitis B
- (2009) Ding-Shinn Chen JOURNAL OF HEPATOLOGY
- Single dose vaccination with AS03-adjuvanted H5N1 vaccines in a randomized trial induces strong and broad immune responsiveness to booster vaccination in adults
- (2009) Tino F. Schwarz et al. VACCINE
- Priming with AS03A-adjuvanted H5N1 influenza vaccine improves the kinetics, magnitude and durability of the immune response after a heterologous booster vaccination: An open non-randomised extension of a double-blind randomised primary study
- (2009) Isabel Leroux-Roels et al. VACCINE
- Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced respiratory syncytial virus disease
- (2008) Maria Florencia Delgado et al. NATURE MEDICINE
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