3.9 Article

Persistence of Antibody to Influenza A/H5N1 Vaccine Virus: Impact of AS03 Adjuvant

Journal

CLINICAL AND VACCINE IMMUNOLOGY
Volume 23, Issue 1, Pages 73-77

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/CVI.00475-15

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Funding

  1. HHS \ NIH \ National Institute of Allergy and Infectious Diseases (NIAID) [HHSN272200800001C, HHSN272200800004C, HHSN27220080000C, HHSN272200800002C, HHSN272200800013C, HHSN272201200003I]

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The adjuvant AS03 is stockpiled for future formulations with new and existing vaccines for the control of pandemic influenza virus. We previously reported the immunogenicity of an A/H5N1 vaccine extemporaneously mixed with the AS03 adjuvant for 42 days following vaccination. This report extends those findings to 1 year after vaccination.

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