(R)-Ketamine attenuates LPS-induced endotoxin-derived delirium through inhibition of neuroinflammation

Electrophysiological signatures of acute systemic lipopolysaccharide-induced inflammation: potential implications for delirium science

(2021) Ziyad W. Sultan et al.   BRITISH JOURNAL OF ANAESTHESIA

Dextran sulfate sodium-induced inflammation and colitis in mice are ameliorated by (R)-ketamine, but not (S)-ketamine: A role of TrkB signaling

(2021) Yuko Fujita et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Molecular mechanisms underlying the antidepressant actions of arketamine: beyond the NMDA receptor

(2021) Yan Wei et al.   MOLECULAR PSYCHIATRY

Neuroprotection by dihydrotestosterone in LPS-induced neuroinflammation

(2020) Lei Yang et al.   NEUROBIOLOGY OF DISEASE

Neuronal brain injury after cerebral ischemic stroke is ameliorated after subsequent administration of (R)-ketamine, but not (S)-ketamine

(2020) Zhongwei Xiong et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

A historical review of antidepressant effects of ketamine and its enantiomers

(2020) Yan Wei et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Maternal glyphosate exposure causes autism-like behaviors in offspring through increased expression of soluble epoxide hydrolase

(2020) Yaoyu Pu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanisms of the rapid-acting and long-lasting antidepressant actions of (R)-ketamine

(2020) Kenji Hashimoto   BIOCHEMICAL PHARMACOLOGY

Acute Inflammation Alters Brain Energy Metabolism in Mice and Humans: Role in Suppressed Spontaneous Activity, Impaired Cognition, and Delirium

(2020) John Kealy et al.   JOURNAL OF NEUROSCIENCE

A key role of the subdiaphragmatic vagus nerve in the depression-like phenotype and abnormal composition of gut microbiota in mice after lipopolysaccharide administration

(2020) Jiancheng Zhang et al.   Translational Psychiatry

Postoperative delirium – treatment and prevention

(2020) Thomas Duning et al.   Current Opinion in Anesthesiology

Bispectral EEG (BSEEG) quantifying neuro-inflammation in mice induced by systemic inflammation: A potential mouse model of delirium

(2020) Takehiko Yamanashi et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Coadministration of Ketamine and Perampanel Improves Behavioral Function and Reduces Inflammation in Acute Traumatic Brain Injury Mouse Model

(2020) Faleh Alqahtani et al.   Biomed Research International

Ketamine Reduces Inflammation Pathways in the Hypothalamus and Hippocampus Following Transient Hypoxia in the Late-Gestation Fetal Sheep

(2019) Eileen I. Chang et al.   Frontiers in Physiology

Exposure to in utero inflammation increases locomotor activity, alters cognitive performance and drives vulnerability to cognitive performance deficits after acute immune activation

(2019) Ryan Makinson et al.   BRAIN BEHAVIOR AND IMMUNITY

Lipid dynamics in LPS-induced neuroinflammation by DESI-MS imaging

(2019) Onésia Cristina Oliveira-Lima et al.   BRAIN BEHAVIOR AND IMMUNITY

Rapid‐acting antidepressant ketamine, its metabolites and other candidates: A historical overview and future perspective

(2019) Kenji Hashimoto   PSYCHIATRY AND CLINICAL NEUROSCIENCES

Contribution of skeletal muscular glycine to rapid antidepressant effects of ketamine in an inflammation-induced mouse model of depression

(2019) Niannian Huang et al.   PSYCHOPHARMACOLOGY

Prophylactic (R,S)-ketamine selectively protects against inflammatory stressors

(2019) Alessia Mastrodonato et al.   BEHAVIOURAL BRAIN RESEARCH

(R)-Ketamine Rapidly Ameliorates the Decreased Spine Density in the Medial Prefrontal Cortex and Hippocampus of Susceptible Mice After Chronic Social Defeat Stress

(2019) Jiancheng Zhang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

MPTP-induced dopaminergic neurotoxicity in mouse brain is attenuated after subsequent intranasal administration of (R)-ketamine: a role of TrkB signaling

(2019) Atsuhiro Fujita et al.   PSYCHOPHARMACOLOGY

Ketamine inhibits LPS‐mediated BV2 microglial inflammation via NMDA receptor blockage

(2019) Yaojun Lu et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Molecular and cellular mechanisms underlying the antidepressant effects of ketamine enantiomers and its metabolites

(2019) Chun Yang et al.   Translational Psychiatry

Microglial Ultrastructure in the Hippocampus of a Lipopolysaccharide-Induced Sickness Mouse Model

(2019) Julie C. Savage et al.   Frontiers in Neuroscience

OUP accepted manuscript

(2018)   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Leucine competes with kynurenine for blood-to-brain transport and prevents lipopolysaccharide-induced depression-like behavior in mice

(2018) Adam K. Walker et al.   MOLECULAR PSYCHIATRY

Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms

(2018) Donal T. Skelly et al.   MOLECULAR PSYCHIATRY

(2R,6R)-Hydroxynorketamine is not essential for the antidepressant actions of (R)-ketamine in mice

(2018) Jun-ichi Yamaguchi et al.   NEUROPSYCHOPHARMACOLOGY

Microglial Activation After Systemic Stimulation With Lipopolysaccharide and Escherichia coli

(2018) Inge C. M. Hoogland et al.   Frontiers in Cellular Neuroscience

MicroRNA-92a antagonism attenuates lipopolysaccharide (LPS)-induced pulmonary inflammation and injury in mice through suppressing the PTEN/AKT/NF-κB signaling pathway

(2018) Liming Fu et al.   BIOMEDICINE & PHARMACOTHERAPY

Lack of Opioid System in the Antidepressant Actions of Ketamine

(2018) Kai Zhang et al.   BIOLOGICAL PSYCHIATRY

Role of Actinobacteria and Coriobacteriia in the antidepressant effects of ketamine in an inflammation model of depression

(2018) Niannian Huang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Hepatoprotective effect of quercetin against LPS/ d -GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways

(2017) Zhixin Peng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

5-Hydroxytryptamine-Independent Antidepressant Actions of (R)-Ketamine in a Chronic Social Defeat Stress Model

(2017) Kai Zhang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Viewpoints: how the hippocampus contributes to memory, navigation and cognition

(2017) John Lisman et al.   NATURE NEUROSCIENCE

Effort but not Reward Sensitivity is Altered by Acute Sickness Induced by Experimental Endotoxemia in Humans

(2017) Amelia Draper et al.   NEUROPSYCHOPHARMACOLOGY

Blockade of interleukin-6 receptor in the periphery promotes rapid and sustained antidepressant actions: a possible role of gut–microbiota–brain axis

(2017) J-c Zhang et al.   Translational Psychiatry

Brain-derived Neurotrophic Factor (BDNF)-TrkB Signaling in Inflammation-related Depression and Potential Therapeutic Targets

(2016) Ji-chun Zhang et al.   Current Neuropharmacology

Battery of behavioral tests in mice to study postoperative delirium

(2016) Mian Peng et al.   Scientific Reports

The Cognitive Neuroscience of Working Memory

(2015) Mark D'Esposito et al.   Annual Review of Psychology

Serum Interleukin-6 Is a Predictive Biomarker for Ketamine’s Antidepressant Effect in Treatment-Resistant Patients With Major Depression

(2015) Jian-jun Yang et al.   BIOLOGICAL PSYCHIATRY

Inflammatory Biomarkers as Differential Predictors of Antidepressant Response

(2015) Kenji Hashimoto   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antidepressant Effects of TrkB Ligands on Depression-Like Behavior and Dendritic Changes in Mice After Inflammation

(2015) Ji-chun Zhang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

IL-17A is implicated in lipopolysaccharide-induced neuroinflammation and cognitive impairment in aged rats via microglial activation

(2015) Jie Sun et al.   Journal of Neuroinflammation

The effect of the antipsychotic drug quetiapine and its metabolite norquetiapine on acute inflammation, memory and anhedonia

(2015) Emily J. Jaehne et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Cognitive decline after sepsis

(2015) Djillali Annane et al.   Lancet Respiratory Medicine

Endotoxin-induced experimental systemic inflammation in humans: A model to disentangle immune-to-brain communication

(2013) Manfred Schedlowski et al.   BRAIN BEHAVIOR AND IMMUNITY

Ketamine and Peripheral Inflammation

(2013) Marc De Kock et al.   CNS Neuroscience & Therapeutics

Cyclooxygenase-1-Dependent Prostaglandins Mediate Susceptibility to Systemic Inflammation-Induced Acute Cognitive Dysfunction

(2013) E. W. Griffin et al.   JOURNAL OF NEUROSCIENCE

Delirium in elderly people

(2013) Sharon K Inouye et al.   LANCET

Systemic Immune Activation Leads to Neuroinflammation and Sickness Behavior in Mice

(2013) Steven Biesmans et al.   MEDIATORS OF INFLAMMATION

Long-Term Cognitive Impairment after Critical Illness

(2013) P.P. Pandharipande et al.   NEW ENGLAND JOURNAL OF MEDICINE

R (−)-ketamine shows greater potency and longer lasting antidepressant effects than S (+)-ketamine

(2013) Ji-chun Zhang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

At the extreme end of the psychoneuroimmunological spectrum: Delirium as a maladaptive sickness behaviour response

(2012) Colm Cunningham et al.   BRAIN BEHAVIOR AND IMMUNITY

Acute Respiratory Distress Syndrome, Sepsis, and Cognitive Decline: A Review and Case Study

(2011) James C. Jackson et al.   SOUTHERN MEDICAL JOURNAL

Effects of Ketamine on Endotoxin and Traumatic Brain Injury Induced Cytokine Production in the Rat

(2011) Jeremy L. Ward et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Systemic inflammation induces acute working memory deficits in the primed brain: relevance for delirium

(2010) Carol Murray et al.   NEUROBIOLOGY OF AGING

Psychological stress suppresses innate IFN-γ production via glucocorticoid receptor activation: Reversal by the anxiolytic chlordiazepoxide

(2009) Niamh M. Curtin et al.   BRAIN BEHAVIOR AND IMMUNITY

Postoperative delirium and cognitive dysfunction

(2009) S. Deiner et al.   BRITISH JOURNAL OF ANAESTHESIA

Re-evaluating dorsolateral prefrontal cortex activation during working memory in schizophrenia

(2009) Katherine H. Karlsgodt et al.   SCHIZOPHRENIA RESEARCH

One-Year Health Care Costs Associated With Delirium in the Elderly Population

(2008) Douglas L. Leslie   ARCHIVES OF INTERNAL MEDICINE

Malaise in the water maze: Untangling the effects of LPS and IL-1β on learning and memory

(2008) Colm Cunningham et al.   BRAIN BEHAVIOR AND IMMUNITY