Dextran sulfate sodium-induced inflammation and colitis in mice are ameliorated by (R)-ketamine, but not (S)-ketamine: A role of TrkB signaling

Intravenous arketamine for treatment-resistant depression: open-label pilot study

(2020) Gustavo C. Leal et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Antidepressants in inflammatory bowel disease

(2020) Antonina Mikocka-Walus et al.   Nature Reviews Gastroenterology & Hepatology

A historical review of antidepressant effects of ketamine and its enantiomers

(2020) Yan Wei et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Altered Peripheral Blood Compounds in Drug-Naïve First-Episode Patients With Either Schizophrenia or Major Depressive Disorder, A Meta-Analysis

(2020) Nuray Çakici et al.   BRAIN BEHAVIOR AND IMMUNITY

Risk of psychosis after repeated intermittent administration of (S)-ketamine, but not (R)-ketamine, in mice

(2020) Yunfei Tan et al.   JOURNAL OF AFFECTIVE DISORDERS

Molecular mechanisms of the rapid-acting and long-lasting antidepressant actions of (R)-ketamine

(2020) Kenji Hashimoto   BIOCHEMICAL PHARMACOLOGY

A key role of the subdiaphragmatic vagus nerve in the depression-like phenotype and abnormal composition of gut microbiota in mice after lipopolysaccharide administration

(2020) Jiancheng Zhang et al.   Translational Psychiatry

Value of peripheral neurotrophin levels for the diagnosis of depression and response to treatment: A systematic review and meta-analysis

(2020) Yachen Shi et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Ketamine: A Paradigm Shift for Depression Research and Treatment

(2019) John H. Krystal et al.   NEURON

Comparison of antidepressant and side effects in mice after intranasal administration of (R,S)-ketamine, (R)-ketamine, and (S)-ketamine

(2019) Lijia Chang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Rapid‐acting antidepressant ketamine, its metabolites and other candidates: A historical overview and future perspective

(2019) Kenji Hashimoto   PSYCHIATRY AND CLINICAL NEUROSCIENCES

Therapeutic ultrasound attenuates DSS-induced colitis through the cholinergic anti-inflammatory pathway

(2019) Natalia Schneider Nunes et al.   EBioMedicine

MPTP-induced dopaminergic neurotoxicity in mouse brain is attenuated after subsequent intranasal administration of (R)-ketamine: a role of TrkB signaling

(2019) Atsuhiro Fujita et al.   PSYCHOPHARMACOLOGY

Molecular and cellular mechanisms underlying the antidepressant effects of ketamine enantiomers and its metabolites

(2019) Chun Yang et al.   Translational Psychiatry

Phencyclidine-induced cognitive deficits in mice are ameliorated by subsequent repeated intermittent administration of (R)-ketamine, but not (S)-ketamine: Role of BDNF-TrkB signaling

(2019) Yunfei Tan et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Mechanistic Target of Rapamycin–Independent Antidepressant Effects of ( R )-Ketamine in a Social Defeat Stress Model

(2018) Chun Yang et al.   BIOLOGICAL PSYCHIATRY

Increased Burden of Psychiatric Disorders in Inflammatory Bowel Disease

(2018) Charles N Bernstein et al.   INFLAMMATORY BOWEL DISEASES

Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms

(2018) Panos Zanos et al.   PHARMACOLOGICAL REVIEWS

Lack of metabolism in (R)-ketamine’s antidepressant actions in a chronic social defeat stress model

(2018) Kai Zhang et al.   Scientific Reports

Evaluation of Brain Activity Using Near-infrared Spectroscopy in Inflammatory Bowel Disease Patients

(2018) Tatsuo Fujiwara et al.   Scientific Reports

An update on ketamine and its two enantiomers as rapid-acting antidepressants

(2018) Kai Zhang et al.   Expert Review of Neurotherapeutics

Depression increases the risk of inflammatory bowel disease, which may be mitigated by the use of antidepressants in the treatment of depression

(2018) Alexandra D Frolkis et al.   GUT

5-Hydroxytryptamine-Independent Antidepressant Actions of (R)-Ketamine in a Chronic Social Defeat Stress Model

(2017) Kai Zhang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Antidepressant Potential of ( R )-Ketamine in Rodent Models: Comparison with ( S )-Ketamine

(2017) Kenichi Fukumoto et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Brain-derived Neurotrophic Factor (BDNF)-TrkB Signaling in Inflammation-related Depression and Potential Therapeutic Targets

(2016) Ji-chun Zhang et al.   Current Neuropharmacology

Reduction of dopamine D2/3 receptor binding in the striatum after a single administration of esketamine, but not R-ketamine: a PET study in conscious monkeys

(2016) Kenji Hashimoto et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Controversies Revisited

(2016) Antonina Mikocka-Walus et al.   INFLAMMATORY BOWEL DISEASES

Depression and anxiety in patients with Inflammatory Bowel Disease: A systematic review

(2016) Rachel Neuendorf et al.   JOURNAL OF PSYCHOSOMATIC RESEARCH

Performance of administrative case definitions for depression and anxiety in inflammatory bowel disease

(2016) Ruth Ann Marrie et al.   JOURNAL OF PSYCHOSOMATIC RESEARCH

Single-dose infusion ketamine and non-ketamine N-methyl-d-aspartate receptor antagonists for unipolar and bipolar depression: a meta-analysis of efficacy, safety and time trajectories

(2016) T. Kishimoto et al.   PSYCHOLOGICAL MEDICINE

BDNF contributes to IBS-like colonic hypersensitivity via activating the enteroglia-nerve unit

(2016) Peng Wang et al.   Scientific Reports

Ketamine and Other NMDA Antagonists: Early Clinical Trials and Possible Mechanisms in Depression

(2015) D. Jeffrey Newport et al.   AMERICAN JOURNAL OF PSYCHIATRY

Comparison of ketamine, 7,8-dihydroxyflavone, and ANA-12 antidepressant effects in the social defeat stress model of depression

(2015) Ji-chun Zhang et al.   PSYCHOPHARMACOLOGY

BDNF–TrkB signaling in the nucleus accumbens shell of mice has key role in methamphetamine withdrawal symptoms

(2015) Q Ren et al.   Translational Psychiatry

R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects

(2015) C Yang et al.   Translational Psychiatry

R (−)-ketamine shows greater potency and longer lasting antidepressant effects than S (+)-ketamine

(2013) Ji-chun Zhang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Decreased Serum Levels of Mature Brain-Derived Neurotrophic Factor (BDNF), but Not Its Precursor proBDNF, in Patients with Major Depressive Disorder

(2012) Taisuke Yoshida et al.   PLoS One

Brain-derived neurotrophic factor as a biomarker for mood disorders: An historical overview and future directions

(2010) Kenji Hashimoto   PSYCHIATRY AND CLINICAL NEUROSCIENCES

The Manitoba IBD Cohort Study: A Population-Based Study of the Prevalence of Lifetime and 12-Month Anxiety and Mood Disorders

(2008) John R. Walker et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY