Landscape of innate lymphoid cells in human head and neck cancer reveals divergent NK cell states in the tumor microenvironment

Tissue Determinants of Human NK Cell Development, Function, and Residence

(2020) Pranay Dogra et al.   CELL

Innate Lymphoid Cell-Epithelial Cell Modules Sustain Intestinal Homeostasis

(2020) Andreas Diefenbach et al.   IMMUNITY

TGF-β and IL-15 Synergize through MAPK Pathways to Drive the Conversion of Human NK Cells to an Innate Lymphoid Cell 1–like Phenotype

(2020) Lindsey G. Hawke et al.   JOURNAL OF IMMUNOLOGY

NR4A transcription factors limit CAR T cell function in solid tumours

(2019) Joyce Chen et al.   NATURE

Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction

(2019) Xindong Liu et al.   NATURE

Spatial and Temporal Mapping of Human Innate Lymphoid Cells Reveals Elements of Tissue Specificity

(2019) Naomi A. Yudanin et al.   IMMUNITY

IL23-Producing Human Lung Cancer Cells Promote Tumor Growth via Conversion of Innate Lymphoid Cell 1 (ILC1) into ILC3

(2019) Jaemoon Koh et al.   CLINICAL CANCER RESEARCH

Determining cell type abundance and expression from bulk tissues with digital cytometry

(2019) Aaron M. Newman et al.   NATURE BIOTECHNOLOGY

Subsets of ILC3−ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues

(2019) Marina Cella et al.   NATURE IMMUNOLOGY

TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8+ T cell exhaustion

(2019) Hyungseok Seo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

True Detective: Unraveling Group 1 Innate Lymphocyte Heterogeneity

(2019) Luke Riggan et al.   TRENDS IN IMMUNOLOGY

The Obese Liver Environment Mediates Conversion of NK Cells to a Less Cytotoxic ILC1-Like Phenotype

(2019) Antonia O. Cuff et al.   Frontiers in Immunology

Inhibition of Nr4a Receptors Enhances Antitumor Immunity by Breaking Treg-Mediated Immune Tolerance

(2018) Sana Hibino et al.   CANCER RESEARCH

Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency

(2018) Yannick Simoni et al.   IMMUNITY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Gene Regulatory Programs Conferring Phenotypic Identities to Human NK Cells

(2018) Patrick L. Collins et al.   CELL

Dissecting human ILC heterogeneity: more than just three subsets

(2017) Yannick Simoni et al.   IMMUNOLOGY

Regulation of the Immune Response by TGF-β: From Conception to Autoimmunity and Infection

(2017) Shomyseh Sanjabi et al.   Cold Spring Harbor Perspectives in Biology

Batch effects and the effective design of single-cell gene expression studies

(2017) Po-Yuan Tung et al.   Scientific Reports

Cancer Immunosurveillance by Tissue-Resident Innate Lymphoid Cells and Innate-like T Cells

(2016) Saïda Dadi et al.   CELL

The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction

(2016) Nicole E. Scharping et al.   IMMUNITY

Human liver-resident CD56bright/CD16neg NK cells are retained within hepatic sinusoids via the engagement of CCR5 and CXCR6 pathways

(2016) Kelly Hudspeth et al.   JOURNAL OF AUTOIMMUNITY

Human CD56brightNK Cells: An Update

(2016) Tatiana Michel et al.   JOURNAL OF IMMUNOLOGY

IL-1 is a critical regulator of group 2 innate lymphoid cell function and plasticity

(2016) Yoichiro Ohne et al.   NATURE IMMUNOLOGY

IL-1β, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs

(2016) Suzanne M Bal et al.   NATURE IMMUNOLOGY

Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs

(2016) Jonathan S Silver et al.   NATURE IMMUNOLOGY

TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway

(2016) Sébastien Viel et al.   Science Signaling

NKp80 Defines a Critical Step during Human Natural Killer Cell Development

(2016) Aharon G. Freud et al.   Cell Reports

TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway

(2016) Sébastien Viel et al.   Science Signaling

Human Circulating and Tissue-Resident CD56bright Natural Killer Cell Populations

(2016) Janine E. Melsen et al.   Frontiers in Immunology

Interleukin-12 and -23 Control Plasticity of CD127+ Group 1 and Group 3 Innate Lymphoid Cells in the Intestinal Lamina Propria

(2015) Jochem H. Bernink et al.   IMMUNITY

The prognostic landscape of genes and infiltrating immune cells across human cancers

(2015) Andrew J Gentles et al.   NATURE MEDICINE

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

Innate Lymphoid Cells in Inflammation and Immunity

(2014) Andrew N.J. McKenzie et al.   IMMUNITY

Gata3drives development of RORγt+group 3 innate lymphoid cells

(2014) Nicolas Serafini et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Think Tank of TINK/TANKs: Tumor-Infiltrating/Tumor-Associated Natural Killer Cells in Tumor Progression and Angiogenesis

(2014) Antonino Bruno et al.   JNCI-Journal of the National Cancer Institute

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Intraepithelial Type 1 Innate Lymphoid Cells Are a Unique Subset of IL-12- and IL-15-Responsive IFN-γ-Producing Cells

(2013) Anja Fuchs et al.   IMMUNITY

Conversion of Peripheral Blood NK Cells to a Decidual NK-like Phenotype by a Cocktail of Defined Factors

(2013) A. S. Cerdeira et al.   JOURNAL OF IMMUNOLOGY

Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues

(2013) Jochem H Bernink et al.   NATURE IMMUNOLOGY

The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote

(2013) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Altered phenotype in peripheral blood and tumor-associated NK cells from colorectal cancer patients

(2012) Yamila S Rocca et al.   Innate Immunity

Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

(2012) Davis J. McCarthy et al.   NUCLEIC ACIDS RESEARCH

The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells

(2011) Takashi Sekiya et al.   Nature Communications

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

(2010) Daniel R. Neill et al.   NATURE

Systemically dispersed innate IL-13-expressing cells in type 2 immunity

(2010) A. E. Price et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

(2009) Kazuyo Moro et al.   NATURE

Microbial Flora Drives Interleukin 22 Production in Intestinal NKp46+ Cells that Provide Innate Mucosal Immune Defense

(2008) Naoko Satoh-Takayama et al.   IMMUNITY

Influence of the transcription factor RORγt on the development of NKp46+ cell populations in gut and skin

(2008) Carmelo Luci et al.   NATURE IMMUNOLOGY

RORγt and commensal microflora are required for the differentiation of mucosal interleukin 22–producing NKp46+ cells

(2008) Stephanie L Sanos et al.   NATURE IMMUNOLOGY