Asiatic acid inhibits angiogenesis and vascular permeability through the VEGF / VEGFR2 signaling pathway to inhibit the growth and metastasis of breast cancer in mice

Vascular Endothelial Growth Factor (VEGF) as a Vital Target for Brain Inflammation during the COVID-19 Outbreak

(2020) Xi-Xi Yin et al.   ACS Chemical Neuroscience

Therapeutic Potential of Centella asiatica and Its Triterpenes: A Review

(2020) Boju Sun et al.   Frontiers in Pharmacology

Role of GPX4-Mediated Ferroptosis in the Sensitivity of Triple Negative Breast Cancer Cells to Gefitinib

(2020) Xiang Song et al.   Frontiers in Oncology

Transforming Growth Factor-β1 Stimulates Mesenchymal Stem Cells Proliferation via Altering Cell Cycle through FAK-Akt-mTOR Pathway

(2019) Jie Sun et al.   CONNECTIVE TISSUE RESEARCH

Alteronol Enhances the Anti-tumor Activity and Reduces the Toxicity of High-Dose Adriamycin in Breast Cancer

(2019) Boxue Ren et al.   Frontiers in Pharmacology

Safety and Pharmacokinetics of Standardized Extract of Centella asiatica (ECa 233) Capsules in Healthy Thai Volunteers: A Phase 1 Clinical Study

(2019) Phanit Songvut et al.   PLANTA MEDICA

Effects of Intestinal Microbial–Elaborated Butyrate on Oncogenic Signaling Pathways

(2019) Jiezhong Chen et al.   Nutrients

S-nitrosylation and its role in breast cancer angiogenesis and metastasis

(2019) Pamela Ehrenfeld et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Integrin α11 cytoplasmic tail is required for FAK activation to initiate 3D cell invasion and ERK-mediated cell proliferation

(2019) Pugazendhi Erusappan et al.   Scientific Reports

Hypoxia and EGF Stimulation Regulate VEGF Expression in Human Glioblastoma Multiforme (GBM) Cells by Differential Regulation of the PI3K/Rho-GTPase and MAPK Pathways

(2019) Samer Nicolas et al.   Cells

Anti-Cancer Effects of Asiatic Acid, A Triterpene From Centilla Asiatica L: A Literature Review

(2019) Muhammad T. Islam et al.   Anti-Cancer Agents in Medicinal Chemistry

VEGF nanoparticles repair the heart after myocardial infarction

(2018) Yasin Oduk et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice

(2018) M. Brown et al.   SCIENCE

Organ-specific metastasis of breast cancer: molecular and cellular mechanisms underlying lung metastasis

(2018) Meysam Yousefi et al.   CELLULAR ONCOLOGY

Pharmacological Properties, Molecular Mechanisms, and Pharmaceutical Development of Asiatic Acid: A Pentacyclic Triterpenoid of Therapeutic Promise

(2018) Mohamed Fizur Nagoor Meeran et al.   Frontiers in Pharmacology

Asiatic acid inhibits lung cancer cell growth in vitro and in vivo by destroying mitochondria

(2017) Tiancong Wu et al.   Acta Pharmaceutica Sinica B

Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy

(2015) C. K. Domigan et al.   JOURNAL OF CELL SCIENCE

VEGF-VEGFR System as a Target for Suppressing Inflammation and other Diseases

(2015) Masabumi Shibuya   Endocrine Metabolic & Immune Disorders-Drug Targets

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Asiatic acid induces endoplasmic reticulum stress and apoptotic death in glioblastoma multiforme cells both in vitro and in vivo

(2014) Chandagirikoppal V. Kavitha et al.   MOLECULAR CARCINOGENESIS

Angiogenesis and the Tumor Microenvironment: Vascular Endothelial Growth Factor and Beyond

(2014) Kriti Mittal et al.   SEMINARS IN ONCOLOGY

Antiangiogenic Triterpenes Isolated from Chinese Herbal Medicine Actinidia chinensis Planch

(2013) Wen-Jun Zhu et al.   Anti-Cancer Agents in Medicinal Chemistry

Upregulated autocrine vascular endothelial growth factor (VEGF)/VEGF receptor-2 loop prevents apoptosis in haemangioma-derived endothelial cells

(2013) Y. Ji et al.   BRITISH JOURNAL OF DERMATOLOGY

VEGFA and tumour angiogenesis

(2013) L. Claesson-Welsh et al.   JOURNAL OF INTERNAL MEDICINE

VEGFR and Type-V RTK Activation and Signaling

(2013) M. Shibuya   Cold Spring Harbor Perspectives in Biology

Increased Expression of P-Glycoprotein Is Associated with Doxorubicin Chemoresistance in the Metastatic 4T1 Breast Cancer Model

(2011) Lili Bao et al.   AMERICAN JOURNAL OF PATHOLOGY

A cell penetrating peptide derived from azurin inhibits angiogenesis and tumor growth by inhibiting phosphorylation of VEGFR-2, FAK and Akt

(2011) Rajeshwari R. Mehta et al.   ANGIOGENESIS

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

Asiatic Acid Inhibits Pro-Angiogenic Effects of VEGF and Human Gliomas in Endothelial Cell Culture Models

(2011) Chandagirikoppal V. Kavitha et al.   PLoS One

Asiatic Acid Induces Colon Cancer Cell Growth Inhibition and Apoptosis through Mitochondrial Death Cascade

(2009) Xue-Lian Tang et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN