An overview on the role of plant-derived tannins for the treatment of lung cancer

Therapeutic potential of plant-derived tannins in non-malignant respiratory diseases

(2021) Subbiah Rajasekaran et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Tannic acid alleviates experimental pulmonary fibrosis in mice by inhibiting inflammatory response and fibrotic process

(2020) Nandhine Rajasekar et al.   INFLAMMOPHARMACOLOGY

Tannic Acid Inhibits Non-small Cell Lung Cancer (NSCLC) Stemness by Inducing G0/G1 Cell Cycle Arrest and Intrinsic Apoptosis

(2020) NIPIN SP et al.   ANTICANCER RESEARCH

Apoptosis as a primary defense mechanism in response to viral infection in invasive fire ant Solenopsis invicta

(2019) Hung-Wei Hsu et al.   VIROLOGY

A PILOT STUDY OF A GRAPE SEED PROCYANIDIN EXTRACT FOR LUNG CANCER CHEMOPREVENTION

(2019) Jenny T Mao et al.   Cancer Prevention Research

Tannic acid prevents macrophage-induced pro-fibrotic response in lung epithelial cells via suppressing TLR4-mediated macrophage polarization

(2019) Ayyanar Sivanantham et al.   INFLAMMATION RESEARCH

Identification of Novel Urolithin Metabolites in Human Feces and Urine after the Intake of a Pomegranate Extract

(2019) Rocío García-Villalba et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Proanthocyanidin-Rich Fractions from Red Rice Extract Enhance TNF-α-Induced Cell Death and Suppress Invasion of Human Lung Adenocarcinoma Cell A549

(2019) Chayaporn Subkamkaew et al.   MOLECULES

Ellagitannins from Punica granatum leaves suppress microsomal prostaglandin E synthase-1 expression and induce lung cancer cells to undergo apoptosis

(2019) Keisuke Toda et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Tannic acid modulates fibroblast proliferation and differentiation in response to pro-fibrotic stimuli

(2018) Dhamotharan Pattarayan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Nanoparticle delivery of grape seed-derived proanthocyanidins to airway epithelial cells dampens oxidative stress and inflammation

(2018) S. Castellani et al.   Journal of Translational Medicine

Grape seed procyanidin extract against lung cancer: the role of microrna-106b, bioavailability, and bioactivity

(2018) Bingye Xue et al.   Oncotarget

Tannic acid protects against experimental acute lung injury through downregulation of TLR4 and MAPK

(2018) Ayyanar Sivanantham et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Oenothein B inhibits human non-small cell lung cancer A549 cell proliferation by ROS-mediated PI3K/Akt/NF-κB signaling pathway

(2018) Xiaodong Pei et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Metformin Sensitizes Non-small Cell Lung Cancer Cells to an Epigallocatechin-3-Gallate (EGCG) Treatment by Suppressing the Nrf2/HO-1 Signaling Pathway

(2017) Chenxiao Yu et al.   International Journal of Biological Sciences

Tannic acid attenuates TGF-β1-induced epithelial-to-mesenchymal transition by effectively intervening TGF-β signaling in lung epithelial cells

(2017) Dhamotharan Pattarayan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Grape Seed Procyanidin Extract Mediates Antineoplastic Effects against Lung Cancer via Modulations of Prostacyclin and 15-HETE Eicosanoid Pathways

(2016) J. T. Mao et al.   Cancer Prevention Research

MicroRNA-19a/b mediates grape seed procyanidin extract-induced anti-neoplastic effects against lung cancer

(2016) Jenny T. Mao et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The International Epidemiology of Lung Cancer: Latest Trends, Disparities, and Tumor Characteristics

(2016) Ting-Yuan David Cheng et al.   Journal of Thoracic Oncology

Urinary metabolites from mango (Mangifera indicaL. cv. Keitt) galloyl derivatives and in vitro hydrolysis of gallotannins in physiological conditions

(2016) Ryan C. Barnes et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Gallic acid induces apoptosis and enhances the anticancer effects of cisplatin in human small cell lung cancer H446 cell line via the ROS-dependent mitochondrial apoptotic pathway

(2016) RUIXUAN WANG et al.   ONCOLOGY REPORTS

Selective antagonization of activated Nrf2 and inhibition of cancer cell proliferation by procyanidins from Cinnamomi Cortex extract

(2015) Tomokazu Ohnuma et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Geraniin inhibits TGF-β1-induced epithelial–mesenchymal transition and suppresses A549 lung cancer migration, invasion and anoikis resistance

(2015) Hyeonseok Ko   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Epigallocatechin-3-Gallate Enhances the Therapeutic Effects of Leptomycin B on Human Lung Cancer A549 Cells

(2015) Meghan M. Cromie et al.   Oxidative Medicine and Cellular Longevity

Bioavailability of Dietary Polyphenols and Gut Microbiota Metabolism: Antimicrobial Properties

(2015) Laura Marín et al.   Biomed Research International

Reversal of Cisplatin Resistance by Epigallocatechin Gallate Is Mediated by Downregulation of Axl and Tyro 3 Expression in Human Lung Cancer Cells

(2014) Kyung-Chan Kim et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Grape seed proanthocyanidins inhibit cigarette smoke condensate-induced lung cancer cell migration through inhibition of NADPH oxidase and reduction in the binding of p22phoxand p47phoxproteins

(2014) Mudit Vaid et al.   MOLECULAR CARCINOGENESIS

Systemic absorption and metabolism of dietary procyanidin B4 in pigs

(2014) Katharina Bittner et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Green tea catechin, epigallocatechin-3-gallate, attenuates the cell viability of human non-small-cell lung cancer A549 cells via reducing Bcl-xL expression

(2014) JUN-ICHIRO SONODA et al.   Experimental and Therapeutic Medicine

Geraniin induces apoptotic cell death in human lung adenocarcinoma A549 cells in vitro and in vivo

(2013) Jia Li et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Synergistic inhibition of lung cancer cell lines by (-)-epigallocatechin-3-gallate in combination with clinically used nitrocatechol inhibitors of catechol-O-methyltransferase

(2013) S. C. Forester et al.   CARCINOGENESIS

Cocoa Phytochemicals: Recent Advances in Molecular Mechanisms on Health

(2013) Jiyoung Kim et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Combination of Low Concentration of (−)-Epigallocatechin Gallate (EGCG) and Curcumin Strongly Suppresses the Growth of Non-Small Cell Lung Cancer in Vitro and in Vivo through Causing Cell Cycle Arrest

(2013) Dong-Hu Zhou et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Procyanidin C1 from Cinnamomi Cortex inhibits TGF-β-induced epithelial-to-mesenchymal transition in the A549 lung cancer cell line

(2013) RYOEI KIN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Anti-Inflammatory Effects of Ellagic Acid on Acute Lung Injury Induced by Acid in Mice

(2013) Daniely Cornélio Favarin et al.   MEDIATORS OF INFLAMMATION

Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship

(2012) Julian R. Molina et al.   MAYO CLINIC PROCEEDINGS

Antioxidant and Antiproliferative Activities of Anthocyanin/Ellagitannin-Enriched Extracts FromSyzygium cuminiL. (Jamun, the Indian Blackberry)

(2012) Farrukh Aqil et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Enhanced sensitivity of A549 cells to the cytotoxic action of anticancer drugs via suppression of Nrf2 by procyanidins from Cinnamomi Cortex extract

(2011) Tomokazu Ohnuma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lung Cancer: Epidemiology, Etiology, and Prevention

(2011) Charles S. Dela Cruz et al.   CLINICS IN CHEST MEDICINE

Interactions of Green Tea Catechins with Organic Anion-Transporting Polypeptides

(2011) M. Roth et al.   DRUG METABOLISM AND DISPOSITION

Toxicology evaluation of a procyanidin-rich extract from grape skins and seeds

(2011) Laura Lluís et al.   FOOD AND CHEMICAL TOXICOLOGY

Chemical Characterization of a Procyanidin-Rich Extract from Sorghum Bran and Its Effect on Oxidative Stress and Tumor Inhibition in Vivo

(2011) Li Wu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Cranberry Proanthocyanidins Mediate Growth Arrest of Lung Cancer Cells through Modulation of Gene Expression and Rapid Induction of Apoptosis

(2011) Laura A. Kresty et al.   MOLECULES

The chemistry and biotransformation of tea constituents

(2011) Shengmin Sang et al.   PHARMACOLOGICAL RESEARCH

Grape Proanthocyanidins Induce Apoptosis by Loss of Mitochondrial Membrane Potential of Human Non-Small Cell Lung Cancer Cells In Vitro and In Vivo

(2011) Tripti Singh et al.   PLoS One

Anticancer property of gallic acid in A549, a human lung adenocarcinoma cell line, and possible mechanisms

(2010) Dharmendra K. Maurya et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Proanthocyanidins Inhibit In vitro and In vivo Growth of Human Non-Small Cell Lung Cancer Cells by Inhibiting the Prostaglandin E2 and Prostaglandin E2 Receptors

(2010) S. D. Sharma et al.   MOLECULAR CANCER THERAPEUTICS

Plant Polyphenols as Dietary Antioxidants in Human Health and Disease

(2010) Kanti Bhooshan Pandey et al.   Oxidative Medicine and Cellular Longevity

Grape Seed Proanthocyanidins Inhibit the Growth of Human Non-Small Cell Lung Cancer Xenografts by Targeting Insulin-Like Growth Factor Binding Protein-3, Tumor Cell Proliferation, and Angiogenic Factors

(2009) S. Akhtar et al.   CLINICAL CANCER RESEARCH

Toxicological evaluation of pomegranate seed oil

(2009) I.A.T.M. Meerts et al.   FOOD AND CHEMICAL TOXICOLOGY

Tannins: Current knowledge of food sources, intake, bioavailability and biological effects

(2009) José Serrano et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Inhibition of non-small cell lung cancer cell migration by grape seed proanthocyanidins is mediated through the inhibition of nitric oxide, guanylate cyclase, and ERK1/2

(2008) Thejass Punathil et al.   MOLECULAR CARCINOGENESIS