The ameliorative effect of terpinen-4-ol on ER stress-induced vascular calcification depends on SIRT1-mediated regulation of PERK acetylation

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(2020) Boris Bikbov et al.   LANCET

Protective effect of EX-527 against high-fat diet-induced diabetic nephropathy in Zucker rats

(2020) Amit Kundu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

SIRT1 Protects the Heart from ER Stress-Induced Injury by Promoting eEF2K/eEF2-Dependent Autophagy

(2020) Julie Pires Da Silva et al.   Cells

Intermedin1-53 attenuates aging-associated vascular calcification in rats by upregulating sirtuin 1

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Loss of SIRT1 in diabetes accelerates DNA damage induced vascular calcification

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Histone Deacetylases in Kidney Physiology and Acute Kidney Injury

(2020) Kelly A. Hyndman   SEMINARS IN NEPHROLOGY

Effects of Terpinen-4-ol on Meibomian Gland Epithelial Cells In Vitro

(2020) Di Chen et al.   CORNEA

PERK controls bone homeostasis through the regulation of osteoclast differentiation and function

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Endoplasmic Reticulum Stress Mediates Vascular Smooth Muscle Cell Calcification via Increased Release of Grp78-Loaded Extracellular Vesicles

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The PERK-EIF2α-ATF4 signaling branch regulates osteoblast differentiation and proliferation by PTH

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Suppression of SIRT1 in Diabetic Conditions Induces Osteogenic Differentiation of Human Vascular Smooth Muscle Cells via RUNX2 Signalling

(2019) F. Bartoli-Leonard et al.   Scientific Reports

Quercetin attenuates oxidative stress-induced apoptosis via SIRT1/AMPK-mediated inhibition of ER stress in rat chondrocytes and prevents the progression of osteoarthritis in a rat model

(2019) Kai Feng et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Pollen Typhae Total Flavone Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis in Human Aortic-Vascular Smooth Muscle Cells through Down-Regulating PERK-eIF2α-ATF4-CHOP Pathway

(2019) Ming-tai Chen et al.   Chinese Journal of Integrative Medicine

Curcumin Inhibits the PERK-eIF2α-CHOP Pathway through Promoting SIRT1 Expression in Oxidative Stress-induced Rat Chondrocytes and Ameliorates Osteoarthritis Progression in a Rat Model

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The Key Role of Phosphate on Vascular Calcification

(2019) Mario Cozzolino et al.   Toxins

Resveratrol, an activator of SIRT1, improves ER stress by increasing clusterin expression in HepG2 cells

(2019) Jinmi Lee et al.   CELL STRESS & CHAPERONES

Differing calcification processes in cultured vascular smooth muscle cells and osteoblasts

(2019) Jessal J. Patel et al.   EXPERIMENTAL CELL RESEARCH

ER stress response mediates diabetic microvascular complications

(2019) Himanshu Sankrityayan et al.   DRUG DISCOVERY TODAY

Ginsenoside Rb1 ameliorates CKD‐associated vascular calcification by inhibiting the Wnt/β‐catenin pathway

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Phosphate-induced ORAI1 expression and store-operated Ca2+ entry in aortic smooth muscle cells

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Endoplasmic reticulum stress, degeneration of pancreatic islet β-cells, and therapeutic modulation of the unfolded protein response in diabetes

(2019) Rajarshi Ghosh et al.   Molecular Metabolism

Monoterpenoid terpinen-4-ol inhibits voltage-dependent Na+ channels of small dorsal root ganglia rat neurons

(2019) Tiago dos Santos-Nascimento et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Oxidative stress contributes to vascular calcification in patients with chronic kidney disease

(2019) Mei Huang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Erythropoietin attenuates vascular calcification by inhibiting endoplasmic reticulum stress in rats with chronic kidney disease

(2019) Jin-Rui Chang et al.   PEPTIDES

Cortistatin inhibits arterial calcification in rats via GSK3β/β-catenin and protein kinase C signalling but not c-Jun N-terminal kinase signalling

(2018) Y. Liu et al.   Acta Physiologica

The Protective Effects of Terpinen-4-ol on LPS-Induced Acute Lung Injury via Activating PPAR-γ

(2018) Jun Ning et al.   INFLAMMATION

Knockdown of Herp alleviates hyperhomocysteinemia mediated atherosclerosis through the inhibition of vascular smooth muscle cell phenotype switching

(2018) Hui Lin et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Laminaria japonica Polysaccharide Inhibits Vascular Calcification via Preventing Osteoblastic Differentiation of Vascular Smooth Muscle Cells

(2018) Xue-Ying Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Sirtuin-1 (SIRT1) stimulates growth-plate chondrogenesis by attenuating the PERK–eIF-2α–CHOP pathway in the unfolded protein response

(2018) Xiaomin Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PDGFR-β modulates vascular smooth muscle cell phenotype via IRF-9/SIRT-1/NF-κB pathway in subarachnoid hemorrhage rats

(2018) Weifeng Wan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Natural products targeting ER stress pathway for the treatment of cardiovascular diseases

(2018) Ker Woon Choy et al.   PHARMACOLOGICAL RESEARCH

Resveratrol attenuates hyperproliferation of vascular smooth muscle cells from spontaneously hypertensive rats: Role of ROS and ROS-mediated cell signaling

(2018) Sara Almajdoob et al.   VASCULAR PHARMACOLOGY

Conditioned medium from bone marrow-derived mesenchymal stem cells inhibits vascular calcification through blockade of the BMP2–Smad1/5/8 signaling pathway

(2018) Shuangshuang Wang et al.   Stem Cell Research & Therapy

Advanced glycation end products accelerate calcification in VSMCs through HIF-1α/PDK4 activation and suppress glucose metabolism

(2018) Yi Zhu et al.   Scientific Reports

Functions and mechanisms of non-histone protein acetylation

(2018) Takeo Narita et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Diethyl citrate and sodium citrate reduce the cytotoxic effects of nanosized hydroxyapatite crystals on mouse vascular smooth muscle cells

(2017) Chong-Yu Zhang et al.   International Journal of Nanomedicine

Terpinen-4-ol inhibits colorectal cancer growth via reactive oxygen species

(2017) Ken Nakayama et al.   Oncology Letters

Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells

(2017) Ioana Alesutan et al.   Scientific Reports

Oestrogen Inhibits Arterial Calcification by Promoting Autophagy

(2017) Yi-Qun Peng et al.   Scientific Reports

Arterial Calcification in Diabetes MellitusHighlights

(2016) John N. Stabley et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A novel organ culture model of aorta for vascular calcification

(2016) Takuyu Akiyoshi et al.   ATHEROSCLEROSIS

SIRT1 protects the heart from ER stress-induced cell death through eIF2α deacetylation

(2016) Alexandre Prola et al.   CELL DEATH AND DIFFERENTIATION

Endoplasmic Reticulum Stress-Mediated Apoptosis Contributing to High Glucose-Induced Vascular Smooth Muscle Cell Calcification

(2015) Qiang Zhu et al.   JOURNAL OF VASCULAR RESEARCH

Terpinen-4-ol Induces Autophagic and Apoptotic Cell Death in Human Leukemic HL-60 Cells

(2014) Ratana Banjerdpongchai et al.   Asian Pacific Journal of Cancer Prevention

Inhibition of vascular calcification by block of intermediate conductance calcium-activated potassium channels with TRAM-34

(2014) Christian Freise et al.   PHARMACOLOGICAL RESEARCH

Endoplasmic Reticulum Stress Effector CCAAT/Enhancer‐binding Protein Homologous Protein (CHOP) Regulates Chronic Kidney Disease–Induced Vascular Calcification

(2014) Shinobu Miyazaki‐Anzai et al.   Journal of the American Heart Association

PERK‐eIF2α‐ATF4‐CHOP Signaling Contributes to TNFα‐Induced Vascular Calcification

(2013) Masashi Masuda et al.   Journal of the American Heart Association

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(2012) D. Gomez et al.   CARDIOVASCULAR RESEARCH

Smooth Muscle Cell–Specific Runx2 Deficiency Inhibits Vascular Calcification

(2012) Yong Sun et al.   CIRCULATION RESEARCH

Activating transcription factor 4 regulates stearate-induced vascular calcification

(2012) Masashi Masuda et al.   JOURNAL OF LIPID RESEARCH

Sirtuin 1 Retards Hyperphosphatemia-Induced Calcification of Vascular Smooth Muscle Cells

(2011) Aya Takemura et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Bone morphogenetic protein-2 activates NADPH oxidase to increase endoplasmic reticulum stress and human coronary artery smooth muscle cell calcification

(2011) Marcel Liberman et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53

(2011) C. Zhang et al.   CARDIOVASCULAR RESEARCH

Estrogen Inhibits Vascular Calcification via Vascular RANKL System

(2010) Mariana Kiomy Osako et al.   CIRCULATION RESEARCH

Nonhistone protein acetylation as cancer therapy targets

(2010) Brahma N Singh et al.   Expert Review of Anticancer Therapy

Endoplasmic reticulum stress-mediated apoptosis is activated in vascular calcification

(2009) Xiaohui Duan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Epigenetic histone acetylation modifiers in vascular remodelling: new targets for therapy in cardiovascular disease

(2009) D. Pons et al.   EUROPEAN HEART JOURNAL

Coronary Calcium as a Predictor of Coronary Events in Four Racial or Ethnic Groups

(2008) Robert Detrano et al.   NEW ENGLAND JOURNAL OF MEDICINE