Quercetin attenuates oxidative stress-induced apoptosis via SIRT1/AMPK-mediated inhibition of ER stress in rat chondrocytes and prevents the progression of osteoarthritis in a rat model

Protective effects of quercetin against inflammation and oxidative stress in a rabbit model of knee osteoarthritis

(2019) Bing Wei et al.   DRUG DEVELOPMENT RESEARCH

Quercetin attenuates mitochondrial dysfunction and biogenesis via upregulated AMPK/SIRT1 signaling pathway in OA rats

(2018) Linan Qiu et al.   BIOMEDICINE & PHARMACOTHERAPY

Sirtuin-1 (SIRT1) stimulates growth-plate chondrogenesis by attenuating the PERK–eIF-2α–CHOP pathway in the unfolded protein response

(2018) Xiaomin Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppression of Sestrins in aging and osteoarthritic cartilage: dysfunction of an important stress defense mechanism

(2017) T. Shen et al.   OSTEOARTHRITIS AND CARTILAGE

Trehalose ameliorates oxidative stress-mediated mitochondrial dysfunction and ER stress via selective autophagy stimulation and autophagic flux restoration in osteoarthritis development

(2017) Qian Tang et al.   Cell Death & Disease

ROS/oxidative stress signaling in osteoarthritis

(2016) Panagiotis Lepetsos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Quercetin and the mitochondria: A mechanistic view

(2016) Marcos Roberto de Oliveira et al.   BIOTECHNOLOGY ADVANCES

Advanced oxidation protein products induce apoptosis of human chondrocyte through reactive oxygen species-mediated mitochondrial dysfunction and endoplasmic reticulum stress pathways

(2016) Wenbin Ye et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Free fatty acid palmitate activates unfolded protein response pathway and promotes apoptosis in meniscus cells

(2016) J. Haywood et al.   OSTEOARTHRITIS AND CARTILAGE

Quercetin reduced inflammation and increased antioxidant defense in rat adjuvant arthritis

(2015) C. Gardi et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Baicalein Inhibits MMPs Expression via a MAPK-Dependent Mechanism in Chondrocytes

(2015) Wei-Ping Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Crocin and quercetin prevent PAT-induced apoptosis in mammalian cells: Involvement of ROS-mediated ER stress pathway

(2015) Manel Boussabbeh et al.   ENVIRONMENTAL TOXICOLOGY

Quercetin is a potent anti-atherosclerotic compound by activation of SIRT1 signaling under oxLDL stimulation

(2015) Ching-Hsia Hung et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Quercetin ameliorates tunicamycin-induced endoplasmic reticulum stress in endothelial cells

(2014) N. Suganya et al.   CELL PROLIFERATION

Quercetin reduces obesity-associated ATM infiltration and inflammation in mice: a mechanism including AMPKα1/SIRT1

(2014) Jing Dong et al.   JOURNAL OF LIPID RESEARCH

The AMPK Inhibitor Compound C Is a Potent AMPK-Independent Antiglioma Agent

(2014) X. Liu et al.   MOLECULAR CANCER THERAPEUTICS

Endoplasmic reticulum stress-induced apoptosis contributes to articular cartilage degeneration via C/EBP homologous protein

(2014) Y. Uehara et al.   OSTEOARTHRITIS AND CARTILAGE

Brief Report: Stress-Inducible Nuclear Protein 1 Regulates Matrix Metalloproteinase 13 Expression in Human Articular Chondrocytes

(2014) Raghunatha R. Yammani et al.   Arthritis & Rheumatology

ATF6 upregulates XBP1S and inhibits ER stress-mediated apoptosis in osteoarthritis cartilage

(2013) Feng-Jin Guo et al.   CELLULAR SIGNALLING

Mitochondria and Reactive Oxygen Species: Physiology and Pathophysiology

(2013) Subhashini Bolisetty et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Comparison of biological processes induced in HepG2 cells by tert-butyl hydroperoxide (t-BHP) and hydroperoxide (H2O2): The influence of carvacrol

(2013) Darina Slamenova et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Reactive Oxygen Species: The 2-Edged Sword of Osteoarthritis

(2012) Ding Li et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Protective effects of quercetin against apoptosis and oxidative stress in streptozotocin-induced diabetic rat testis

(2011) Mehmet Kanter et al.   FOOD AND CHEMICAL TOXICOLOGY

Mammalian Sirtuins: Biological Insights and Disease Relevance

(2010) Marcia C. Haigis et al.   Annual Review of Pathology-Mechanisms of Disease

SirT1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathway

(2010) Viktoria Gagarina et al.   ARTHRITIS AND RHEUMATISM

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the rat

(2010) N. Gerwin et al.   OSTEOARTHRITIS AND CARTILAGE

SIRT1 regulation of apoptosis of human chondrocytes

(2009) Koji Takayama et al.   ARTHRITIS AND RHEUMATISM

Advanced Osteoarthritis in Humans Is Associated With Altered Collagen VI Expression and Upregulation of ER-stress Markers Grp78 and Bag-1

(2009) Ashleigh E. Nugent et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

SIRT1 and insulin resistance

(2009) Fengxia Liang et al.   Nature Reviews Endocrinology

Involvement of p38 MAPK in regulation of MMP13 mRNA in chondrocytes in response to surviving stress to endoplasmic reticulum

(2008) Kazunori Hamamura et al.   ARCHIVES OF ORAL BIOLOGY

Regulation of Cartilage-specific Gene Expression in Human Chondrocytes by SirT1 and Nicotinamide Phosphoribosyltransferase

(2008) Mona Dvir-Ginzberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY