Induced Pluripotent Stem Cells (iPSCs) Provide a Potentially Unlimited T Cell Source for CAR-T Cell Development and Off-the-Shelf Products
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Title
Induced Pluripotent Stem Cells (iPSCs) Provide a Potentially Unlimited T Cell Source for CAR-T Cell Development and Off-the-Shelf Products
Authors
Keywords
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Journal
PHARMACEUTICAL RESEARCH
Volume 38, Issue 6, Pages 931-945
Publisher
Springer Science and Business Media LLC
Online
2021-06-11
DOI
10.1007/s11095-021-03067-z
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Note: Only part of the references are listed.- A clinically applicable and scalable method to regenerate T-cells from iPSCs for off-the-shelf T-cell immunotherapy
- (2021) Shoichi Iriguchi et al. Nature Communications
- Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma
- (2021) Nikhil C. Munshi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Autologous CAR T-cell therapies supply chain: challenges and opportunities?
- (2020) Maria M. Papathanasiou et al. CANCER GENE THERAPY
- Paving the way towards universal treatment with allogenic T cells
- (2020) Michelle H. Townsend et al. IMMUNOLOGIC RESEARCH
- ‘Off-the-shelf’ allogeneic CAR T cells: development and challenges
- (2020) S. Depil et al. NATURE REVIEWS DRUG DISCOVERY
- Adoptive Cell Therapy Targeting Neoantigens: A Frontier for Cancer Research
- (2020) Zhidong Wang et al. Frontiers in Immunology
- KTE-X19 CAR T-Cell Therapy in Relapsed or Refractory Mantle-Cell Lymphoma
- (2020) Michael Wang et al. NEW ENGLAND JOURNAL OF MEDICINE
- Pluripotent Stem Cell-Based Cell Therapy—Promise and Challenges
- (2020) Shinya Yamanaka Cell Stem Cell
- Chimeric Antigen Receptor Based Therapy as a Potential Approach in Autoimmune Diseases: How Close Are We to the Treatment?
- (2020) Muhammad Sadeqi Nezhad et al. Frontiers in Immunology
- Naive T cell deficits at diagnosis and after chemotherapy impair cell therapy potential in pediatric cancers
- (2019) Rajat K Das et al. Cancer Discovery
- Tumorigenicity assay essential for facilitating safety studies of hiPSC-derived cardiomyocytes for clinical application
- (2019) Emiko Ito et al. Scientific Reports
- Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility
- (2019) Huaigeng Xu et al. Cell Stem Cell
- Recent Updates on Induced Pluripotent Stem Cells in Hematological Disorders
- (2019) Methichit Wattanapanitch Stem Cells International
- Novel biomanufacturing platform for large-scale and high-quality human T cells production
- (2019) Jianfa Ou et al. Journal of Biological Engineering
- Phase I Clinical Trial Using Autologous Ex Vivo Expanded NK Cells and Cytotoxic T Lymphocytes for Cancer Treatment in Vietnam
- (2019) Nguyen Thanh Liem et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Induced Pluripotent Stem Cell (iPSC)–Derived Lymphocytes for Adoptive Cell Immunotherapy: Recent Advances and Challenges
- (2019) Alexandros Nianias et al. Current Hematologic Malignancy Reports
- Generation of two induced pluripotent stem cell lines (MUSIi011-A and MUSIi011-B) from peripheral blood T lymphocytes of a healthy individual
- (2019) Ratchapong Netsrithong et al. Stem Cell Research
- CD8+ T-Cell Response to HIV Infection in the Era of Antiretroviral Therapy
- (2019) Federico Perdomo-Celis et al. Frontiers in Immunology
- Time-Varying Effects of Graft Type on Outcomes for Patients with Acute Myeloid Leukemia Undergoing Allogeneic Hematopoietic Cell Transplantation
- (2019) Masamitsu Yanada et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Applications and explorations of CRISPR/Cas9 in CAR T-cell therapy
- (2019) Chenggong Li et al. Briefings in Functional Genomics
- Current challenges and emerging opportunities of CAR-T cell therapies
- (2019) Teresa R. Abreu et al. JOURNAL OF CONTROLLED RELEASE
- High Frequency Production of T Cell-Derived iPSC Clones Capable of Generating Potent Cytotoxic T Cells
- (2019) Seiji Nagano et al. Molecular Therapy-Methods & Clinical Development
- Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity
- (2018) Ye Li et al. Cell Stem Cell
- Genetic and epigenetic factors which modulate differentiation propensity in human pluripotent stem cells
- (2018) Alexander Keller et al. HUMAN REPRODUCTION UPDATE
- Chimeric Antigen Receptor T Cell Therapy: Challenges to Bench-to-Bedside Efficacy
- (2018) Shivani Srivastava et al. JOURNAL OF IMMUNOLOGY
- Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia
- (2018) Shannon L. Maude et al. NEW ENGLAND JOURNAL OF MEDICINE
- Monitoring cell line identity in collections of human induced pluripotent stem cells
- (2018) Raquel Sarafian et al. Stem Cell Research
- The Pharmacology of T Cell Therapies
- (2018) Michael C. Milone et al. Molecular Therapy-Methods & Clinical Development
- Delivery approaches for CRISPR/Cas9 therapeutics in vivo: advances and challenges
- (2018) D.C. Luther et al. Expert Opinion on Drug Delivery
- Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell
- (2018) Marco Ruella et al. NATURE MEDICINE
- Quality control guidelines for clinical-grade human induced pluripotent stem cell lines
- (2018) Stephen Sullivan et al. Regenerative Medicine
- Using intracellular markers to identify a novel set of surface markers for live cell purification from a heterogeneous hIPSC culture
- (2018) Elizabeth J. Paik et al. Scientific Reports
- A retrospective comparison of allogenic and autologous chimeric antigen receptor T cell therapy targeting CD19 in patients with relapsed/refractory acute lymphoblastic leukemia
- (2018) Yongxian Hu et al. BONE MARROW TRANSPLANTATION
- Enhancing T Cell Receptor Stability in Rejuvenated iPSC-Derived T Cells Improves Their Use in Cancer Immunotherapy
- (2018) Atsutaka Minagawa et al. Cell Stem Cell
- Adoptive cellular therapies: the current landscape
- (2018) Maartje W. Rohaan et al. VIRCHOWS ARCHIV
- Need for high-resolution Genetic Analysis in iPSC: Results and Lessons from the ForIPS Consortium
- (2018) Bernt Popp et al. Scientific Reports
- An insight into non-integrative gene delivery approaches to generate transgene-free induced pluripotent stem cells
- (2018) Krishna Kumar Haridhasapavalan et al. GENE
- Systematic in vitro and in vivo characterization of Leukemia-inhibiting factor- and Fibroblast growth factor-derived porcine induced pluripotent stem cells
- (2017) Jan O. Secher et al. MOLECULAR REPRODUCTION AND DEVELOPMENT
- Targeted cellular immunotherapy for T cell malignancies
- (2017) Teresa Palomero et al. NATURE MEDICINE
- Chimeric Antigen Receptor T Cells in Refractory B-Cell Lymphomas
- (2017) Stephen J. Schuster et al. NEW ENGLAND JOURNAL OF MEDICINE
- Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma
- (2017) Sattva S. Neelapu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Two sides of the same coin? Unraveling subtle differences between human embryonic and induced pluripotent stem cells by Raman spectroscopy
- (2017) Elvira Parrotta et al. Stem Cell Research & Therapy
- Systematic evaluation of markers used for the identification of human induced pluripotent stem cells
- (2017) Sumitha Prameela Bharathan et al. Biology Open
- Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation
- (2017) Marek Wieczorek et al. Frontiers in Immunology
- The Immunogenicity and Immune Tolerance of Pluripotent Stem Cell Derivatives
- (2017) Xin Liu et al. Frontiers in Immunology
- T-cell defect in diffuse large B-cell lymphomas involves expansion of myeloid-derived suppressor cells
- (2016) I. Azzaoui et al. BLOOD
- Regeneration of CD8αβ T Cells from T-cell–Derived iPSC Imparts Potent Tumor Antigen-Specific Cytotoxicity
- (2016) Takuya Maeda et al. CANCER RESEARCH
- T-cell acute lymphoblastic leukemia
- (2016) E. A. Raetz et al. Hematology-American Society of Hematology Education Program
- Reprogramming of Melanoma Tumor-Infiltrating Lymphocytes to Induced Pluripotent Stem Cells
- (2016) Hidehito Saito et al. Stem Cells International
- Clinical manufacturing of CAR T cells: foundation of a promising therapy
- (2016) Xiuyan Wang et al. Molecular Therapy-Oncolytics
- Challenges and opportunities of allogeneic donor-derived CAR T cells
- (2015) Yinmeng Yang et al. CURRENT OPINION IN HEMATOLOGY
- 721. Safety of Multiple Doses of CAR T Cells
- (2015) Kristen Fousek et al. MOLECULAR THERAPY
- Epigenetics, plasticity, and evolution: How do we link epigenetic change to phenotype?
- (2014) Elizabeth J. Duncan et al. JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION
- Molecular architecture of the αβ T cell receptor–CD3 complex
- (2014) Michael E. Birnbaum et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Induction of pluripotency in bone marrow mononuclear cells via polyketal nanoparticle-mediated delivery of mature microRNAs
- (2013) Young-Doug Sohn et al. BIOMATERIALS
- Donor-derived CD19-targeted T cells cause regression of malignancy persisting after allogeneic hematopoietic stem cell transplantation
- (2013) J. N. Kochenderfer et al. BLOOD
- Regeneration of Human Tumor Antigen-Specific T Cells from iPSCs Derived from Mature CD8 + T Cells
- (2013) Raul Vizcardo et al. Cell Stem Cell
- Generation of Rejuvenated Antigen-Specific T Cells by Reprogramming to Pluripotency and Redifferentiation
- (2013) Toshinobu Nishimura et al. Cell Stem Cell
- Lin28: Primal Regulator of Growth and Metabolism in Stem Cells
- (2013) Ng Shyh-Chang et al. Cell Stem Cell
- Simplified process for the production of anti–CD19-CAR–engineered T cells
- (2013) Barbara Tumaini et al. CYTOTHERAPY
- Persistence and Efficacy of Second Generation CAR T Cell Against the LeY Antigen in Acute Myeloid Leukemia
- (2013) David S. Ritchie et al. MOLECULAR THERAPY
- Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer therapy
- (2013) Maria Themeli et al. NATURE BIOTECHNOLOGY
- High-throughput fingerprinting of human pluripotent stem cell fate responses and lineage bias
- (2013) Emanuel J P Nazareth et al. NATURE METHODS
- Transferred WT1-Reactive CD8+ T Cells Can Mediate Antileukemic Activity and Persist in Post-Transplant Patients
- (2013) A. G. Chapuis et al. Science Translational Medicine
- Optimized Surface Markers for the Prospective Isolation of High-Quality hiPSCs using Flow Cytometry Selection
- (2013) Ramzey Abujarour et al. Scientific Reports
- Generating an iPSC Bank for HLA-Matched Tissue Transplantation Based on Known Donor and Recipient HLA Types
- (2012) Craig J. Taylor et al. Cell Stem Cell
- Screening of human pluripotent stem cells using CGH and FISH reveals low-grade mosaic aneuploidy and a recurrent amplification of chromosome 1q
- (2012) Michal Dekel-Naftali et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Lessons from human teratomas to guide development of safe stem cell therapies
- (2012) Justine J Cunningham et al. NATURE BIOTECHNOLOGY
- Residual Expression of the Reprogramming Factors Prevents Differentiation of iPSC Generated from Human Fibroblasts and Cord Blood CD34+ Progenitors
- (2012) Verónica Ramos-Mejía et al. PLoS One
- Novel Live Alkaline Phosphatase Substrate for Identification of Pluripotent Stem Cells
- (2012) Upinder Singh et al. Stem Cell Reviews and Reports
- Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias
- (2011) R. J. Brentjens et al. BLOOD
- Genome Sequencing of Mouse Induced Pluripotent Stem Cells Reveals Retroelement Stability and Infrequent DNA Rearrangement during Reprogramming
- (2011) Aaron R. Quinlan et al. Cell Stem Cell
- Reprogramming of Mouse and Human Cells to Pluripotency Using Mature MicroRNAs
- (2011) Norikatsu Miyoshi et al. Cell Stem Cell
- Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T-Cell Transfer Immunotherapy
- (2011) S. A. Rosenberg et al. CLINICAL CANCER RESEARCH
- Ligation of the CD2 co-stimulatory receptor enhances IL-2 production from first-generation chimeric antigen receptor T cells
- (2011) E J Cheadle et al. GENE THERAPY
- Karyotypic abnormalities in human induced pluripotent stem cells and embryonic stem cells
- (2011) Seth M Taapken et al. NATURE BIOTECHNOLOGY
- Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells
- (2011) Kitai Kim et al. NATURE BIOTECHNOLOGY
- A human memory T cell subset with stem cell–like properties
- (2011) Luca Gattinoni et al. NATURE MEDICINE
- Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors
- (2011) H. Ban et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Establishment of human induced pluripotent stem cell lines from normal fibroblast TIG-1
- (2011) Tsutomu Kumazaki et al. Human Cell
- Role of Oct4 in maintaining and regaining stem cell pluripotency
- (2011) Guilai Shi et al. Stem Cell Research & Therapy
- Role of donor lymphocyte infusions in relapsed hematological malignancies after stem cell transplantation revisited
- (2010) Abhinav Deol et al. CANCER TREATMENT REVIEWS
- Reprogramming of T Cells from Human Peripheral Blood
- (2010) Yuin-Han Loh et al. Cell Stem Cell
- Reprogramming of Human Peripheral Blood Cells to Induced Pluripotent Stem Cells
- (2010) Judith Staerk et al. Cell Stem Cell
- Generation of Induced Pluripotent Stem Cells from Human Terminally Differentiated Circulating T Cells
- (2010) Tomohisa Seki et al. Cell Stem Cell
- Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA
- (2010) Luigi Warren et al. Cell Stem Cell
- The International Stem Cell Banking Initiative (ISCBI): raising standards to bank on
- (2010) Jeremy Micah Crook et al. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
- High Resolution Array-CGH Characterization of Human Stem Cells Using a Stem Cell Focused Microarray
- (2010) Aaron M. Elliott et al. MOLECULAR BIOTECHNOLOGY
- Generation of adult human induced pluripotent stem cells using nonviral minicircle DNA vectors
- (2010) Kazim H Narsinh et al. Nature Protocols
- Generation of induced pluripotent stem cells from newborn marmoset skin fibroblasts
- (2010) Yuehong Wu et al. Stem Cell Research
- Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
- (2009) L. A. Johnson et al. BLOOD
- Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins
- (2009) Dohoon Kim et al. Cell Stem Cell
- Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins
- (2009) Hongyan Zhou et al. Cell Stem Cell
- A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells
- (2009) Hitoshi Niwa et al. NATURE
- Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon
- (2009) Kosuke Yusa et al. NATURE METHODS
- The Molecular Mechanism of Induced Pluripotency: A Two-Stage Switch
- (2009) Wouter Scheper et al. Stem Cell Reviews and Reports
- Adenoviral Gene Delivery Can Reprogram Human Fibroblasts to Induced Pluripotent Stem Cells
- (2009) Wenbo Zhou et al. STEM CELLS
- Induced Pluripotent Stem Cells Generated Without Viral Integration
- (2008) M. Stadtfeld et al. SCIENCE
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