One-Pot Transformation of Furans into 1-Azaspirocyclic Alkaloid Frameworks Induced by Visible Light

Principle and design of pseudo-natural products

(2020) George Karageorgis et al.   Nature Chemistry

Photocatalytic α‐Tertiary Amine Synthesis via C–H Alkylation of Unmasked Primary Amines

(2020) Alexander James Cresswell et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ag-Catalyzed Oxidative ipso-Cyclization via Decarboxylative Acylation/Alkylation: Access to 3-Acyl/Alkyl-spiro[4.5]trienones

(2020) Chada Raji Reddy et al.   ORGANIC LETTERS

Scalable Synthesis of Biologically Relevant Spirocyclic Pyrrolidines

(2019) Kostiantyn P. Melnykov et al.   ACS Omega

Fluvirosaones A and B, Two Indolizidine Alkaloids with a Pentacyclic Skeleton from Flueggea virosa

(2018) Xiang-Kun Luo et al.   ORGANIC LETTERS

The Power of Triplet and Singlet Oxygen in Synthesis: 2-Oxindoles, 3-Hydroxy-2-oxindoles, and Isatins from Furans

(2018) Myron Triantafyllakis et al.   ORGANIC LETTERS

Green and Bio-Based Solvents

(2018) Francisco G. Calvo-Flores et al.   Topics in Current Chemistry

Visible-light-enabled spirocyclization of alkynes leading to 3-sulfonyl and 3-sulfenyl azaspiro[4,5]trienones

(2017) Wei Wei et al.   GREEN CHEMISTRY

Intramolecular Aza-Piancatelli Rearrangement of Alkyl- or Arylamines Promoted by PPh3/Diethyl Azodicarboxylate

(2017) Zhong-Li Xu et al.   ORGANIC LETTERS

Synthesis of Tricyclic Marine Alkaloids, Cylindricines, Lepadiformines, Fasicularin, and Polycitorols: A Recent Update

(2017) Shunsuke Chiba et al.   SYNTHESIS-STUTTGART

Boronic Acid Catalysis for Aza-Piancatelli Rearrangement

(2017) Wen-Hua Zheng et al.   SYNTHESIS-STUTTGART

Iron-catalyzed cascade cyanoalkylation/radical dearomatization of N-phenylcinnamamides: access to cyanoalkylated 1-azaspiro[4.5]decanes

(2017) Honglin Zhang et al.   Organic Chemistry Frontiers

Straightforward and effective synthesis of γ-aminobutyric acid transporter subtype 2-selective acyl-substituted azaspiro[4.5]decanes

(2016) Xiaofeng Ma et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Metal-free tandem oxidative C(sp3)–H bond functionalization of alkanes and dearomatization of N-phenyl-cinnamamides: access to alkylated 1-azaspiro[4.5]decanes

(2016) Honglin Zhang et al.   CHEMICAL COMMUNICATIONS

Singlet-Oxygen-Initiated Tandem Transformation of 2-Hexylfuran to the Natural Alkaloids Glochidine and Glochidicine

(2016) Georgios I. Ioannou et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

An Alkylidene Carbene C–H Activation Approach toward the Enantioselective Syntheses of Spirolactams: Application to the Synthesis of (−)-Adalinine

(2016) Krishna Annadi et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-Catalyzed Oxidative ipso-Annulation of Activated Alkynes with Silanes: An Approach to 3-Silyl Azaspiro[4,5]trienones

(2016) Pin Gao et al.   ORGANIC LETTERS

Pot economy and one-pot synthesis

(2016) Yujiro Hayashi   Chemical Science

Stereochemical Outcomes in Reductive Cyclizations To Form Spirocyclic Heterocycles

(2015) Matthew A. Perry et al.   ORGANIC LETTERS

First Total Synthesis of Pandamarine

(2015) Dimitris Kalaitzakis et al.   ORGANIC LETTERS

Rhodium(III)-Catalyzed [3+2] Annulation of 5-Aryl-2,3-dihydro-1H-pyrroles with Internal Alkynes through C(sp2)H/Alkene Functionalization

(2014) Ming-Bo Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The use of spirocyclic scaffolds in drug discovery

(2014) Yajun Zheng et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Furans and singlet oxygen – why there is more to come from this powerful partnership

(2014) Tamsyn Montagnon et al.   CHEMICAL COMMUNICATIONS

Four-Membered Ring-Containing Spirocycles: Synthetic Strategies and Opportunities

(2014) Erick M. Carreira et al.   CHEMICAL REVIEWS

Biology-Oriented Synthesis: Harnessing the Power of Evolution

(2014) Hilde van Hattum et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic, enantioselective vinylogous Michael reactions

(2014) Christoph Schneider et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of γ-butenolides and α,β-unsaturated γ-butyrolactams by addition of vinylogous nucleophiles to Michael acceptors

(2014) Xavier Jusseau et al.   TETRAHEDRON

One-pot synthesis of 1-azaspiro frameworks initiated by photooxidation of simple furans

(2013) Dimitris Kalaitzakis et al.   CHEMICAL COMMUNICATIONS

From Simple Furans to Complex Nitrogen-Bearing Aromatic Polycycles by Means of a Flexible and General Reaction Sequence Initiated by Singlet Oxygen

(2013) Dimitris Kalaitzakis et al.   CHEMISTRY-A EUROPEAN JOURNAL

General One-Pot Reductivegem-Bis-Alkylation of Tertiary Lactams/Amides: Rapid Construction of 1-Azaspirocycles and Formal Total Synthesis of (±)-Cephalotaxine

(2013) Kai-Jiong Xiao et al.   CHEMISTRY-A EUROPEAN JOURNAL

One-pot Synthesis of the Tetracyclic Framework of the Aromatic Erythrina Alkaloids from Simple Furans

(2013) Dimitris Kalaitzakis et al.   ORGANIC LETTERS

A Versatile Synthesis of Meyers’ Bicyclic Lactams from Furans: Singlet-Oxygen-Initiated Reaction Cascade

(2012) Dimitris Kalaitzakis et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Natural products from Cephalotaxus sp.: chemical diversity and synthetic aspects

(2012) Hajer Abdelkafi et al.   NATURAL PRODUCT REPORTS

Direct and Highly Diastereoselective Synthesis of Azaspirocycles by a Dysprosium(III) Triflate Catalyzed Aza-Piancatelli Rearrangement

(2011) Leoni I. Palmer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aiming for the Ideal Synthesis

(2010) Tanja Gaich et al.   JOURNAL OF ORGANIC CHEMISTRY

The chemistry of Stemona alkaloids: An update

(2010) Ronaldo Aloise Pilli et al.   NATURAL PRODUCT REPORTS

Redox Economy in Organic Synthesis

(2009) Noah Z. Burns et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The economies of synthesis

(2009) Timothy Newhouse et al.   CHEMICAL SOCIETY REVIEWS

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

(2009) Frank Lovering et al.   JOURNAL OF MEDICINAL CHEMISTRY

Protecting-group-free synthesis as an opportunity for invention

(2009) Ian S. Young et al.   Nature Chemistry

Function-Oriented Synthesis, Step Economy, and Drug Design

(2007) Paul A. Wender et al.   ACCOUNTS OF CHEMICAL RESEARCH