The metabolic role of spermidine in obesity: Evidence from cells to community

Modern pharmacological treatment of obese patients

(2020) Marcus May et al.   Therapeutic Advances in Endocrinology and Metabolism

Chemical activation of SAT1 corrects diet-induced metabolic syndrome

(2020) Francesca Castoldi et al.   CELL DEATH AND DIFFERENTIATION

Spermidine, an autophagy inducer, as a therapeutic strategy in neurological disorders

(2020) Indrani Ghosh et al.   NEUROPEPTIDES

Type 2 Diabetes Is Associated with a Different Pattern of Serum Polyamines: A Case–Control Study from the PREDIMED-Plus Trial

(2019) Jose Fernandez-Garcia et al.   Journal of Clinical Medicine

Higher spermidine intake is linked to lower mortality: a prospective population-based study

(2018) Stefan Kiechl et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Spermidine/spermine N1-acetyltransferase-mediated polyamine catabolism regulates beige adipocyte biogenesis

(2018) Fang Yuan et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Spermidine ameliorates non-alcoholic fatty liver disease through regulating lipid metabolism via AMPK

(2018) Mingyue Gao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mechanisms of Insulin Action and Insulin Resistance

(2018) Max C. Petersen et al.   PHYSIOLOGICAL REVIEWS

Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans?

(2018) Frank Madeo et al.   Autophagy

Spermidine and Voluntary Activity Exert Differential Effects on Sucrose- Compared with Fat-Induced Systemic Changes in Male Mice

(2018) Julia Schipke et al.   JOURNAL OF NUTRITION

Mitochondrial reactive oxygen species and adipose tissue thermogenesis: Bridging physiology and mechanisms

(2017) Edward T. Chouchani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy couteracts weight gain, lipotoxicity and pancreatic β-cell death upon hypercaloric pro-diabetic regimens

(2017) Álvaro F Fernández et al.   Cell Death & Disease

Spermidine alleviates experimental autoimmune encephalomyelitis through inducing inhibitory macrophages

(2016) Q Yang et al.   CELL DEATH AND DIFFERENTIATION

Cardioprotection and lifespan extension by the natural polyamine spermidine

(2016) Tobias Eisenberg et al.   NATURE MEDICINE

Metabolic Disturbances Identified in Plasma Are Associated With Outcomes in Patients With Heart Failure

(2015) Mei-Ling Cheng et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Enhanced insulin sensitivity in skeletal muscle and liver by physiological overexpression of SIRT6

(2015) Jason G. Anderson et al.   Molecular Metabolism

Spermidine induces autophagy by inhibiting the acetyltransferase EP300

(2014) F Pietrocola et al.   CELL DEATH AND DIFFERENTIATION

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity

(2014) Daniel Kraus et al.   NATURE

Evaluation of early weight loss thresholds for identifying nonresponders to an intensive lifestyle intervention

(2014) Jessica L. Unick et al.   Obesity

Modulation of polyamine metabolic flux in adipose tissue alters the accumulation of body fat by affecting glucose homeostasis

(2013) Chunli Liu et al.   AMINO ACIDS

Toxicity of Polyamines and Their Metabolic Products

(2013) Anthony E. Pegg   CHEMICAL RESEARCH IN TOXICOLOGY

Fibroblast growth factor 21 is a metabolic regulator that plays a role in the adaptation to ketosis

(2011) Eleni M Domouzoglou et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The activation of hepatic and muscle polyamine catabolism improves glucose homeostasis

(2011) Taina Koponen et al.   AMINO ACIDS

Polyamine flux analysis by determination of heavy isotope incorporation from 13C, 15N-enriched amino acids into polyamines by LC–MS/MS

(2011) Marc Cerrada-Gimenez et al.   AMINO ACIDS

Neuroendocrine regulation of autophagy by leptin

(2011) Shoaib Ahmad Malik et al.   CELL CYCLE

Polyamines Are Increased in Obese Children and Are Related to Markers of Oxidative/Nitrosative Stress and Angiogenesis

(2011) Pilar Codoñer-Franch et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Polyamines in foods: development of a food database

(2011) Mohamed Atiya Ali et al.   Food & Nutrition Research

The early history of polyamine research

(2010) Uriel Bachrach   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Polyamines: Potential anti-inflammatory agents and their possible mechanism of action

(2009) SureshRamnath Naik et al.   INDIAN JOURNAL OF PHARMACOLOGY

Spermidine is indispensable in differentiation of 3T3-L1 fibroblasts to adipocytes

(2009) Susanna Vuohelainen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Induction of autophagy by spermidine promotes longevity

(2009) Tobias Eisenberg et al.   NATURE CELL BIOLOGY