YB-1 unwinds mRNA secondary structures in vitro and negatively regulates stress granule assembly in HeLa cells

YBX1 is required for maintaining myeloid leukemia cell survival by regulating BCL2 stability in an m6A-dependent manner

(2021) Mengdie Feng et al.   BLOOD

Lin28, a major translation reprogramming factor, gains access to YB-1-packaged mRNA through its cold-shock domain

(2021) Anastasiia Samsonova et al.   Communications Biology

Modulation of RNA Condensation by the DEAD-Box Protein eIF4A

(2020) Devin Tauber et al.   CELL

Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging

(2020) Shuai Ma et al.   CELL

Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization

(2020) David W. Sanders et al.   CELL

G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules

(2020) Peiguo Yang et al.   CELL

RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation

(2020) Jordina Guillén-Boixet et al.   CELL

Pooled CRISPR screens with imaging on microraft arrays reveals stress granule-regulatory factors

(2020) Emily C. Wheeler et al.   NATURE METHODS

Regulation of RNA granules by FMRP and implications for neurological diseases

(2020) Austin Lai et al.   TRAFFIC

Structural basis of DNA binding to human YB-1 cold shock domain regulated by phosphorylation

(2020) Jingfeng Zhang et al.   NUCLEIC ACIDS RESEARCH

The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer

(2020) Minakshi Gandhi et al.   Nature Communications

Splicing factor YBX1 mediates persistence of JAK2-mutated neoplasms

(2020) Ashok Kumar Jayavelu et al.   NATURE

RNA structure maps across mammalian cellular compartments

(2019) Lei Sun et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RNA structure drives interaction with proteins

(2019) Natalia Sanchez de Groot et al.   Nature Communications

Class I HDAC inhibitors enhance YB ‐1 acetylation and oxidative stress to block sarcoma metastasis

(2019) Amal M El‐Naggar et al.   EMBO REPORTS

YB-1 Expression and Phosphorylation Regulate Tumorigenicity and Invasiveness in Melanoma by Influencing EMT

(2018) Corinna Kosnopfel et al.   MOLECULAR CANCER RESEARCH

A Stress Response that Monitors and Regulates mRNA Structure Is Central to Cold Shock Adaptation

(2018) Yan Zhang et al.   MOLECULAR CELL

Analyses of mRNA structure dynamics identify embryonic gene regulatory programs

(2018) Jean-Denis Beaudoin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RNA self-assembly contributes to stress granule formation and defining the stress granule transcriptome

(2018) Briana Van Treeck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analyses of mRNA structure dynamics identify embryonic gene regulatory programs

(2018) Jean-Denis Beaudoin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The multifunctional protein YB-1 potentiates PARP1 activity and decreases the efficiency of PARP1 inhibitors

(2018) Elizaveta Alemasova et al.   Oncotarget

Cold shock proteins: from cellular mechanisms to pathophysiology and disease

(2018) Jonathan A. Lindquist et al.   Cell Communication and Signaling

Stress Granules and Processing Bodies in Translational Control

(2018) Pavel Ivanov et al.   Cold Spring Harbor Perspectives in Biology

YB-1, an abundant core mRNA-binding protein, has the capacity to form an RNA nucleoprotein filament: a structural analysis

(2018) Dmitry A Kretov et al.   NUCLEIC ACIDS RESEARCH

Long noncoding RNA HULC modulates the phosphorylation of YB-1 through serving as a scaffold of extracellular signal-regulated kinase and YB-1 to enhance hepatocarcinogenesis

(2017) Dan Li et al.   HEPATOLOGY

LIN28 Zinc Knuckle Domain Is Required and Sufficient to Induce let-7 Oligouridylation

(2017) Longfei Wang et al.   Cell Reports

Dynamics of Translation of Single mRNA Molecules In Vivo

(2016) Xiaowei Yan et al.   CELL

YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression

(2016) Shawn M. Lyons et al.   NUCLEIC ACIDS RESEARCH

Distinct stages in stress granule assembly and disassembly

(2016) Joshua R Wheeler et al.   eLife

The Clothes Make the mRNA: Past and Present Trends in mRNP Fashion

(2015) Guramrit Singh et al.   Annual Review of Biochemistry

Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis

(2015) Amal M. El-Naggar et al.   CANCER CELL

YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1

(2015) Syam Prakash Somasekharan et al.   JOURNAL OF CELL BIOLOGY

Genome-wide analysis of YB-1-RNA interactions reveals a novel role of YB-1 in miRNA processing in glioblastoma multiforme

(2015) Shuai-Lai Wu et al.   NUCLEIC ACIDS RESEARCH

mRNA and DNA selection via protein multimerization: YB-1 as a case study

(2015) Dmitry A. Kretov et al.   NUCLEIC ACIDS RESEARCH

YBX1/YB-1 induces partial EMT and tumourigenicity through secretion of angiogenic factors into the extracellular microenvironment

(2015) Shashi K. Gopal et al.   Oncotarget

Functional characterization of C. elegans Y-box-binding proteins reveals tissue-specific functions and a critical role in the formation of polysomes

(2014) Andreas Arnold et al.   NUCLEIC ACIDS RESEARCH

Stress granules are dispensable for mRNA stabilization during cellular stress

(2014) Nadine Bley et al.   NUCLEIC ACIDS RESEARCH

Free mRNA in excess upon polysome dissociation is a scaffold for protein multimerization to form stress granules

(2014) Ouissame Bounedjah et al.   NUCLEIC ACIDS RESEARCH

Ultradeep Human Phosphoproteome Reveals a Distinct Regulatory Nature of Tyr and Ser/Thr-Based Signaling

(2014) Kirti Sharma et al.   Cell Reports

Roles of YB-1 under arsenite-induced stress: Translational activation of HSP70 mRNA and control of the number of stress granules

(2013) Toru Tanaka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo

(2013) Silvi Rouskin et al.   NATURE

YB-1 protein: functions and regulation

(2013) Dmitry N. Lyabin et al.   Wiley Interdisciplinary Reviews-RNA

The feed-forward loop between YB-1 and MYC is essential for multiple myeloma cell survival

(2012) K S Bommert et al.   LEUKEMIA

Deep proteome and transcriptome mapping of a human cancer cell line

(2011) N. Nagaraj et al.   Molecular Systems Biology

Translational Activation of Snail1 and Other Developmentally Regulated Transcription Factors by YB-1 Promotes an Epithelial-Mesenchymal Transition

(2009) Valentina Evdokimova et al.   CANCER CELL

Novel DNA mismatch-repair activity involving YB-1 in human mitochondria

(2009) Nadja C. de Souza-Pinto et al.   DNA REPAIR

TDP-43 is recruited to stress granules in conditions of oxidative insult

(2009) Claudia Colombrita et al.   JOURNAL OF NEUROCHEMISTRY

SUnSET, a nonradioactive method to monitor protein synthesis

(2009) Enrico K Schmidt et al.   NATURE METHODS

Concordant Regulation of Translation and mRNA Abundance for Hundreds of Targets of a Human microRNA

(2009) David G. Hendrickson et al.   PLOS BIOLOGY