Magnetic Resonance Imaging of Blood–Brain Barrier permeability in Dementia

A four-dimensional computational model of dynamic contrast-enhanced magnetic resonance imaging measurement of subtle blood-brain barrier leakage

(2021) Jose Bernal et al.   NEUROIMAGE

Sex-Related Differences in Regional Blood–Brain Barrier Integrity in Non-Demented Elderly Subjects

(2021) Yeonsil Moon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Increase of blood-brain barrier leakage is related to cognitive decline in vascular mild cognitive impairment

(2021) Man Li et al.   BMC Neurology

Sources of systematic error in DCE‐MRI estimation of low‐level blood‐brain barrier leakage

(2021) Cameron Manning et al.   MAGNETIC RESONANCE IN MEDICINE

Baseline Blood-Brain Barrier Leakage and Longitudinal Microstructural Tissue Damage in the Periphery of White Matter Hyperintensities

(2021) Danielle Kerkhofs et al.   NEUROLOGY

Interplay between Brain Pericytes and Endothelial Cells in Dementia

(2021) Tessa V. Procter et al.   AMERICAN JOURNAL OF PATHOLOGY

A novel sensitive assay for detection of a biomarker of pericyte injury in cerebrospinal fluid

(2020) Melanie D. Sweeney et al.   Alzheimers & Dementia

Hypercapnia exacerbates the disruption of the blood‑brain barrier by inducing interleukin‑1β overproduction in the blood of hypoxemic adult rats

(2020) Hongguang Ding et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline

(2020) Axel Montagne et al.   NATURE

Brain Microvascular Pericytes in Vascular Cognitive Impairment and Dementia

(2020) Maiko T. Uemura et al.   Frontiers in Aging Neuroscience

Iron leakage owing to blood-brain barrier disruption in small vessel disease CADASIL

(2020) Yuto Uchida et al.   NEUROLOGY

Increase in blood–brain barrier leakage in healthy, older adults

(2020) Inge C. M. Verheggen et al.   GeroScience

Imaging the role of blood–brain barrier disruption in normal cognitive ageing

(2020) Inge C. M. Verheggen et al.   GeroScience

Comparison Between Blood-Brain Barrier Water Exchange Rate and Permeability to Gadolinium-Based Contrast Agent in an Elderly Cohort

(2020) Xingfeng Shao et al.   Frontiers in Neuroscience

Vascular dysfunction—The disregarded partner of Alzheimer's disease

(2019) Melanie D. Sweeney et al.   Alzheimers & Dementia

Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction

(2019) Daniel A. Nation et al.   NATURE MEDICINE

Blood-brain barrier impairment and hypoperfusion are linked in cerebral small vessel disease

(2019) Sau May Wong et al.   NEUROLOGY

Quantifying blood-brain barrier leakage in small vessel disease: Review and consensus recommendations

(2019) Michael J. Thrippleton et al.   Alzheimers & Dementia

Small vessel disease: mechanisms and clinical implications

(2019) Joanna M Wardlaw et al.   LANCET NEUROLOGY

The relationship between blood–brain barrier permeability and enlarged perivascular spaces: a cross-sectional study

(2019) Yue Li et al.   Clinical Interventions in Aging

Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss

(2019) Angeliki M. Nikolakopoulou et al.   NATURE NEUROSCIENCE

White matter hyperintensities mediate the association between blood-brain barrier leakage and information processing speed

(2019) Whitney M. Freeze et al.   NEUROBIOLOGY OF AGING

Undetectable gadolinium brain retention in individuals with an age-dependent blood-brain barrier breakdown in the hippocampus and mild cognitive impairment

(2019) Axel Montagne et al.   Alzheimers & Dementia

Blood-Brain Barrier Disruption and Perivascular Beta-Amyloid Accumulation in the Brain of Aged Rats with Spontaneous Hypertension: Evaluation with Dynamic Contrast-Enhanced Magnetic Resonance Imaging

(2018) Yu Wang et al.   KOREAN JOURNAL OF RADIOLOGY

Pericyte degeneration causes white matter dysfunction in the mouse central nervous system

(2018) Axel Montagne et al.   NATURE MEDICINE

Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

(2018) Melanie D. Sweeney et al.   Nature Reviews Neurology

MRI measurements of Blood-Brain Barrier function in dementia: A review of recent studies

(2018) Rajikha Raja et al.   NEUROPHARMACOLOGY

Compromised Blood–Brain Barrier Integrity Is Associated With Total Magnetic Resonance Imaging Burden of Cerebral Small Vessel Disease

(2018) Yue Li et al.   Frontiers in Neurology

The role of brain vasculature in neurodegenerative disorders

(2018) Melanie D. Sweeney et al.   NATURE NEUROSCIENCE

Extravascular fibrinogen in the white matter of Alzheimer's disease and normal aged brains: implications for fibrinogen as a biomarker for Alzheimer's disease

(2018) Kirsty E. McAleese et al.   BRAIN PATHOLOGY

Blood-Brain Barrier: From Physiology to Disease and Back

(2018) Melanie D. Sweeney et al.   PHYSIOLOGICAL REVIEWS

Differing associations between Aβ accumulation, hypoperfusion, blood–brain barrier dysfunction and loss of PDGFRB pericyte marker in the precuneus and parietal white matter in Alzheimer's disease

(2017) J Scott Miners et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Alzheimer’s disease: A matter of blood–brain barrier dysfunction?

(2017) Axel Montagne et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Higher blood–brain barrier permeability is associated with higher white matter hyperintensities burden

(2017) Yue Li et al.   JOURNAL OF NEUROLOGY

Subtle blood-brain barrier leakage rate and spatial extent: Considerations for dynamic contrast-enhanced MRI

(2017) Harm J. van de Haar et al.   MEDICAL PHYSICS

Hypothalamic stem cells control ageing speed partly through exosomal miRNAs

(2017) Yalin Zhang et al.   NATURE

The quantification of blood-brain barrier disruption using dynamic contrast-enhanced magnetic resonance imaging in aging rhesus monkeys with spontaneous type 2 diabetes mellitus

(2017) Ziqian Xu et al.   NEUROIMAGE

Brain imaging of neurovascular dysfunction in Alzheimer’s disease

(2016) Axel Montagne et al.   ACTA NEUROPATHOLOGICA

Neurovascular unit impairment in early Alzheimer's disease measured with magnetic resonance imaging

(2016) Harm J. van de Haar et al.   NEUROBIOLOGY OF AGING

Tracer kinetic modelling for DCE-MRI quantification of subtle blood–brain barrier permeability

(2016) Anna K. Heye et al.   NEUROIMAGE

Blood–brain barrier leakage is more widespread in patients with cerebral small vessel disease

(2016) C. Eleana Zhang et al.   NEUROLOGY

Blood-Brain Barrier Leakage in Patients with Early Alzheimer Disease

(2016) Harm J. van de Haar et al.   RADIOLOGY

Pericytes are involved in the pathogenesis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy

(2015) Mitrajit Ghosh et al.   ANNALS OF NEUROLOGY

Establishment and Dysfunction of the Blood-Brain Barrier

(2015) Zhen Zhao et al.   CELL

Accelerated pericyte degeneration and blood–brain barrier breakdown in apolipoprotein E4 carriers with Alzheimer’s disease

(2015) Matthew R Halliday et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Validation of biomarkers in subcortical ischaemic vascular disease of the Binswanger type: approach to targeted treatment trials

(2015) G. A. Rosenberg et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Optimal acquisition and modeling parameters for accurate assessment of low Ktransblood-brain barrier permeability using dynamic contrast-enhanced MRI

(2015) Samuel R. Barnes et al.   MAGNETIC RESONANCE IN MEDICINE

Blood-Brain Barrier Breakdown in the Aging Human Hippocampus

(2015) Axel Montagne et al.   NEURON

Long-Term Blood–Brain Barrier Permeability Changes in Binswanger Disease

(2015) Branko N. Huisa et al.   STROKE

Capillary pericytes regulate cerebral blood flow in health and disease

(2014) Catherine N. Hall et al.   NATURE

Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer’s Coordinating Centre

(2013) Jon B. Toledo et al.   BRAIN

Pericyte loss influences Alzheimer-like neurodegeneration in mice

(2013) Abhay P. Sagare et al.   Nature Communications

Deficiency in Mural Vascular Cells Coincides with Blood-Brain Barrier Disruption in Alzheimer's Disease

(2012) Jesse D. Sengillo et al.   BRAIN PATHOLOGY

The vascular factor in Alzheimer's disease: A study in Golgi technique and electron microscopy

(2012) Stavros J. Baloyannis et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

(2011) Berislav V. Zlokovic   NATURE REVIEWS NEUROSCIENCE

Determination of the venous output function from MR signal phase: Feasibility for quantitative DCE-MRI in human brain

(2010) Claire Foottit et al.   MAGNETIC RESONANCE IN MEDICINE

Correlations of Neuronal and Microvascular Densities in Murine Cortex Revealed by Direct Counting and Colocalization of Nuclei and Vessels

(2009) P. S. Tsai et al.   JOURNAL OF NEUROSCIENCE

Bolus-tracking MRI with a simultaneousT1- andT2*-measurement

(2009) S. Sourbron et al.   MAGNETIC RESONANCE IN MEDICINE

Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery

(2009) Muge Yemisci et al.   NATURE MEDICINE

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON