Cathepsin C aggravates neuroinflammation via promoting production of CCL2 and CXCL2 in glial cells and neurons in a cryogenic brain lesion

Penetrating Traumatic Brain Injury Triggers Subacute Dysregulation of Cathepsin B Protein Levels Independently of Cysteine Protease Activity in Brain and Cerebral Spinal Fluid

(2020) Angela Boutte et al.   JOURNAL OF NEUROTRAUMA

The Role of Selected Chemokines and Their Receptors in the Development of Gliomas

(2020) Magdalena Groblewska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Associations between serum L-arginine and ficolins in the early phase of acute ischemic stroke – A pilot study

(2020) Tihamer Molnar et al.   Journal of Stroke & Cerebrovascular Diseases

The Role of Astrocytes in CNS Inflammation

(2020) Federico Giovannoni et al.   TRENDS IN IMMUNOLOGY

High-resolution and differential analysis of rat microglial markers in traumatic brain injury: conventional flow cytometric and bioinformatics analysis

(2020) Naama Toledano Furman et al.   Scientific Reports

Interaction of Microglia and Astrocytes in the Neurovascular Unit

(2020) Li-rong Liu et al.   Frontiers in Immunology

Astrocyte Crosstalk in CNS Inflammation

(2020) Mathias Linnerbauer et al.   NEURON

Cathepsin C promotes microglia M1 polarization and aggravates neuroinflammation via activation of Ca2+-dependent PKC/p38MAPK/NF-κB pathway

(2019) Qing Liu et al.   Journal of Neuroinflammation

Staphylococcus aureus infected embolic stroke upregulates Orm1 and Cxcl2 in a rat model of septic stroke pathology

(2019) Lærke Boye Astrup et al.   NEUROLOGICAL RESEARCH

Chemokines: Key Molecules that Orchestrate Communication among Neurons, Microglia and Astrocytes to Preserve Brain Function

(2019) Flavia Trettel et al.   NEUROSCIENCE

Chemokine CCL2 contributes to BBB disruption via the p38 MAPK signaling pathway following acute intracerebral hemorrhage

(2019) Fuyou Guo et al.   FASEB JOURNAL

Increase in chemokine CXCL1 by ERβ ligand treatment is a key mediator in promoting axon myelination

(2018) Hawra Karim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cathepsin C Modulates Myelin Oligodendrocyte Glycoprotein-induced Experimental Autoimmune Encephalomyelitis

(2018) Wilaiwan Wisessmith et al.   JOURNAL OF NEUROCHEMISTRY

Affective, neurocognitive and psychosocial disorders associated with traumatic brain injury and post-traumatic epilepsy

(2018) Bridgette D. Semple et al.   NEUROBIOLOGY OF DISEASE

Macrophage biology in the peripheral nervous system after injury

(2018) Richard E. Zigmond et al.   PROGRESS IN NEUROBIOLOGY

How do chemokines navigate neutrophils to the target site: Dissecting the structural mechanisms and signaling pathways

(2018) Krishna Rajarathnam et al.   CELLULAR SIGNALLING

The balance between cathepsin C and cystatin F controls remyelination in the brain of Plp1 -overexpressing mouse, a chronic demyelinating disease model

(2017) Takahiro Shimizu et al.   GLIA

The far-reaching scope of neuroinflammation after traumatic brain injury

(2017) Dennis W. Simon et al.   Nature Reviews Neurology

Neuroimmunology of Traumatic Brain Injury: Time for a Paradigm Shift

(2017) Yasir N. Jassam et al.   NEURON

Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases

(2016) Yveline Hamon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ammonia Attenuates LPS-Induced Upregulation of Pro-Inflammatory Cytokine mRNA in Co-Cultured Astrocytes and Microglia

(2016) Ayse Karababa et al.   NEUROCHEMICAL RESEARCH

Disinhibition of Cathepsin C Caused by Cystatin F Deficiency Aggravates the Demyelination in a Cuprizone Model

(2016) Junjie Liang et al.   Frontiers in Molecular Neuroscience

Neuroinflammation: Ways in Which the Immune System Affects the Brain

(2015) Richard M. Ransohoff et al.   Neurotherapeutics

Priming the Inflammatory Pump of the CNS after Traumatic Brain Injury

(2015) Kristina G. Witcher et al.   TRENDS IN NEUROSCIENCES

Inflammatory reaction after traumatic brain injury: therapeutic potential of targeting cell–cell communication by chemokines

(2015) Stefka Gyoneva et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Dipeptidyl Peptidase I-Dependent Neutrophil Recruitment Modulates the Inflammatory Response to Sendai Virus Infection

(2014) A. M. Akk et al.   JOURNAL OF IMMUNOLOGY

Mast cell and macrophage chemokines CXCL1/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation

(2013) K. De Filippo et al.   BLOOD

Glia and epilepsy: Experimental investigation of antiepileptic drugs in an astroglia/microglia co-culture model of inflammation

(2013) Hannes Dambach et al.   EPILEPSIA

Current status of chemokines in the adult CNS

(2013) Annabelle Réaux-Le Goazigo et al.   PROGRESS IN NEUROBIOLOGY

Inflammatory cell trafficking across the blood-brain barrier: chemokine regulation and in vitro models

(2012) Yukio Takeshita et al.   IMMUNOLOGICAL REVIEWS

Up-regulation of microglial cathepsin C expression and activity in lipopolysaccharide-induced neuroinflammation

(2012) Kai Fan et al.   Journal of Neuroinflammation

Regulation of neutrophil trafficking from the bone marrow

(2011) Ryan B. Day et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mouse MCP1 C-terminus inhibits human MCP1-induced chemotaxis and BBB compromise

(2011) Yao Yao et al.   JOURNAL OF NEUROCHEMISTRY

Microglial cystatin F expression is a sensitive indicator for ongoing demyelination with concurrent remyelination

(2011) Jianmei Ma et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Systemic administration of lipopolysaccharide induces molecular and morphological alterations in the hippocampus

(2010) Grzegorz A. Czapski et al.   BRAIN RESEARCH

Pioglitazone attenuates mitochondrial dysfunction, cognitive impairment, cortical tissue loss, and inflammation following traumatic brain injury

(2010) Andrew Sauerbeck et al.   EXPERIMENTAL NEUROLOGY

Traumatic Brain Injury: A Disease Process, Not an Event

(2010) Brent E. Masel et al.   JOURNAL OF NEUROTRAUMA

What has inflammation to do with traumatic brain injury?

(2009) David Cederberg et al.   CHILDS NERVOUS SYSTEM

Moderate and severe traumatic brain injury in adults

(2008) Andrew IR Maas et al.   LANCET NEUROLOGY