Antioxidant Effect of Hydroxytyrosol, Hydroxytyrosol Acetate and Nitrohydroxytyrosol in a Rat MPP+ Model of Parkinson’s Disease

Neurotoxic Mechanism of Arsenic: Synergistic Effect of Mitochondrial Instability, Oxidative Stress, and Hormonal-Neurotransmitter Impairment

(2020) Nandita Medda et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Healthy Effects of Plant Polyphenols: Molecular Mechanisms

(2020) Manuela Leri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effects of postprandial hydroxytyrosol and derivates on oxidation of LDL, cardiometabolic state and gene expression

(2019) Marco A. Perrone et al.   Journal of Cardiovascular Medicine

Di (2‐ethylhexyl) phthalate targets the thioredoxin system and the oxidative branch of the pentose phosphate pathway in liver of Balb/c mice

(2019) Ines Amara et al.   ENVIRONMENTAL TOXICOLOGY

Hydroxytyrosol butyrate inhibits 6-OHDA-induced apoptosis through activation of the Nrf2/HO-1 axis in SH-SY5Y cells

(2018) Megumi Funakohi-Tago et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Design, synthesis of allosteric peptide activator for human SIRT1 and its biological evaluation in cellular model of Alzheimer's disease

(2017) Rahul Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Changes in blood anti-oxidation enzyme levels in MPTP-treated monkeys

(2017) Like Li et al.   NEUROSCIENCE LETTERS

β-Estradiol-3-benzoate confers neuroprotection in Parkinson MPP + rat model through inhibition of lipid peroxidation

(2017) Yoshajandith Aguirre-Vidal et al.   STEROIDS

Synthesis and Antioxidant Activity of Alkyl Nitroderivatives of Hydroxytyrosol

(2016) Elena Gallardo et al.   MOLECULES

Hydroxytyrosol induces phase II detoxifying enzyme expression and effectively protects dopaminergic cells against dopamine- and 6-hydroxydopamine induced cytotoxicity

(2016) Guohua Yu et al.   NEUROCHEMISTRY INTERNATIONAL

Hydroxytyrosol improves mitochondrial function and reduces oxidative stress in the brain of db/db mice: role of AMP-activated protein kinase activation

(2015) Adi Zheng et al.   BRITISH JOURNAL OF NUTRITION

Differences in the Neuroprotective Effect of Orally Administered Virgin Olive Oil (Olea europaea) Polyphenols Tyrosol and Hydroxytyrosol in Rats

(2015) José Pedro De La Cruz et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Potential Role of Olive Oil Phenolic Compounds in the Prevention of Neurodegenerative Diseases

(2015) Jose Rodríguez-Morató et al.   MOLECULES

Dual protection of hydroxytyrosol, an olive oil polyphenol, against oxidative damage in PC12 cells

(2015) Shoujiao Peng et al.   Food & Function

Synthesis and Antioxidant Activity of Nitrohydroxytyrosol and Its Acyl Derivatives

(2014) Mariana Trujillo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Neuroprotective effect of Buddleja cordata methanolic extract in the 1-methyl-4-phenylpyridinium Parkinson’s disease rat model

(2014) Gabriela Pérez-Barrón et al.   Journal of Natural Medicines

In vivo striatal measurement of hydroxytyrosol, and its metabolite (homovanillic alcohol), compared with its derivative nitrohydroxytyrosol

(2014) Elena Gallardo et al.   NEUROSCIENCE LETTERS

The effect of hydroxytyrosol and its nitroderivatives on catechol-O-methyl transferase activity in rat striatal tissue

(2014) Elena Gallardo et al.   RSC Advances

Cellular stress response, redox status, and vitagenes in glaucoma: a systemic oxidant disorder linked to Alzheimer’s disease

(2014) Angela Trovato Salinaro   Frontiers in Pharmacology

Sex hormonal regulation and hormesis in aging and longevity: role of vitagenes

(2014) V. Calabrese et al.   Journal of Cell Communication and Signaling

Extra virgin olive oil (EVOO) consumption and antioxidant status in healthy institutionalized elderly humans

(2013) María-Jesús Oliveras-López et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Glutathione metabolism and Parkinson's disease

(2013) Michelle Smeyne et al.   FREE RADICAL BIOLOGY AND MEDICINE

SOD1 and DJ-1 Converge at Nrf2 Pathway: A Clue for Antioxidant Therapeutic Potential in Neurodegeneration

(2013) Pamela Milani et al.   Oxidative Medicine and Cellular Longevity

Effects of human Toll-like receptor 1 polymorphisms on ageing

(2013) Peter Uciechowski et al.   Immunity & Ageing

Phenylpropanoid glycosides from plant cell cultures induce heme oxygenase 1 gene expression in a human keratinocyte cell line by affecting the balance of NRF2 and BACH1 transcription factors

(2012) Anna Sgarbossa et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Alperujo extract, hydroxytyrosol, and 3,4-dihydroxyphenylglycol are bioavailable and have antioxidant properties in vitamin E-deficient rats-a proteomics and network analysis approach

(2012) Guillermo Rodríguez-Gutiérrez et al.   MOLECULAR NUTRITION & FOOD RESEARCH

A Diet Rich in Olive Oil Phenolics Reduces Oxidative Stress in the Heart of SAMP8 Mice by Induction of Nrf2-Dependent Gene Expression

(2012) Banu Bayram et al.   REJUVENATION RESEARCH

Stimulation of GSH synthesis to prevent oxidative stress-induced apoptosis by hydroxytyrosol in human retinal pigment epithelial cells: activation of Nrf2 and JNK-p62/SQSTM1 pathways

(2011) Xuan Zou et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Olive oil reduces oxidative damage in a 3-nitropropionic acid-induced Huntington's disease-like rat model

(2011) I Tasset et al.   NUTRITIONAL NEUROSCIENCE

Cellular Stress Responses, The Hormesis Paradigm, and Vitagenes: Novel Targets for Therapeutic Intervention in Neurodegenerative Disorders

(2010) Vittorio Calabrese et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydroxytyrosol protects against oxidative damage by simultaneous activation of mitochondrial biogenesis and phase II detoxifying enzyme systems in retinal pigment epithelial cells

(2010) Lu Zhu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Hydroxytyrosol induces antioxidant/detoxificant enzymes and Nrf2 translocation via extracellular regulated kinases and phosphatidylinositol-3-kinase/protein kinase B pathways in HepG2 cells

(2010) María Angeles Martín et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Human absorption of a supplement containing purified hydroxytyrosol, a natural antioxidant from olive oil, and evidence for its transient association with low-density lipoproteins

(2010) Maria González-Santiago et al.   PHARMACOLOGICAL RESEARCH

Antioxidant activity evaluation of alkyl hydroxytyrosyl ethers, a new class of hydroxytyrosol derivatives

(2008) Gema Pereira-Caro et al.   FOOD CHEMISTRY

Neuroprotective effect of hydroxytyrosol and hydroxytyrosol acetate in rat brain slices subjected to hypoxia–reoxygenation

(2008) José Antonio González-Correa et al.   NEUROSCIENCE LETTERS