Testing physiologically relevant conditions in minimal inhibitory concentration assays

Quantitative Framework for Model Evaluation in Microbiology Research Using Pseudomonas aeruginosa and Cystic Fibrosis Infection as a Test Case

(2020) Daniel M. Cornforth et al.   mBio

Antimicrobial Resistance in ESKAPE Pathogens

(2020) David M. P. De Oliveira et al.   CLINICAL MICROBIOLOGY REVIEWS

Genetic and Chemical Screening in Human Blood Serum Reveals Unique Antibacterial Targets and Compounds against Klebsiella pneumoniae

(2020) Brent S. Weber et al.   Cell Reports

Identification of novel targets of azithromycin activity against Pseudomonas aeruginosa grown in physiologically relevant media

(2020) Corrie R. Belanger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human serum albumin alters specific genes that can play a role in survival and persistence in Acinetobacter baumannii

(2018) Brettni Quinn et al.   Scientific Reports

Correcting a Fundamental Flaw in the Paradigm for Antimicrobial Susceptibility Testing

(2017) Selvi C. Ersoy et al.   EBioMedicine

The Accidental Orthodoxy of Drs. Mueller and Hinton

(2017) Victor Nizet   EBioMedicine

Reversion of High-level Mecillinam Resistance to Susceptibility in Escherichia coli During Growth in Urine

(2017) Elisabeth Thulin et al.   EBioMedicine

Major Transcriptome Changes Accompany the Growth of Pseudomonas aeruginosa in Blood from Patients with Severe Thermal Injuries

(2016) Cassandra Kruczek et al.   PLoS One

Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions

(2016) Ulrike Mäder et al.   PLoS Genetics

RNASeq Based Transcriptional Profiling of Pseudomonas aeruginosa PA14 after Short- and Long-Term Anoxic Cultivation in Synthetic Cystic Fibrosis Sputum Medium

(2016) Muralidhar Tata et al.   PLoS One

Enhanced annotations and features for comparing thousands ofPseudomonasgenomes in the Pseudomonas genome database

(2015) Geoffrey L. Winsor et al.   NUCLEIC ACIDS RESEARCH

Essential genome ofPseudomonas aeruginosain cystic fibrosis sputum

(2015) Keith H. Turner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

General and condition-specific essential functions ofPseudomonas aeruginosa

(2015) Samuel A. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Azithromycin Synergizes with Cationic Antimicrobial Peptides to Exert Bactericidal and Therapeutic Activity Against Highly Multidrug-Resistant Gram-Negative Bacterial Pathogens

(2015) Leo Lin et al.   EBioMedicine

Rethinking the Antibiotic Discovery Paradigm

(2015) Robert E.W. Hancock   EBioMedicine

Host-dependent Induction of Transient Antibiotic Resistance: A Prelude to Treatment Failure

(2015) Jessica Z. Kubicek-Sutherland et al.   EBioMedicine

Clinically Relevant Growth Conditions Alter Acinetobacter baumannii Antibiotic Susceptibility and Promote Identification of Novel Antibacterial Agents

(2015) Jennifer M. Colquhoun et al.   PLoS One

CFTR, Mucins, and Mucus Obstruction in Cystic Fibrosis

(2013) S. M. Kreda et al.   Cold Spring Harbor Perspectives in Medicine

Mucin Promotes Rapid Surface Motility in Pseudomonas aeruginosa

(2012) A. T. Y. Yeung et al.   mBio

In Vivo-Validated Essential Genes Identified in Acinetobacter baumannii by Using Human Ascites Overlap Poorly with Essential Genes Detected on Laboratory Media

(2012) T. C. Umland et al.   mBio

Use of Artificial Sputum Medium to Test Antibiotic Efficacy Against Pseudomonas aeruginosa in Conditions More Relevant to the Cystic Fibrosis Lung

(2012) Sebastian Kirchner et al.   Jove-Journal of Visualized Experiments

Global Changes in Staphylococcus aureus Gene Expression in Human Blood

(2011) Natalia Malachowa et al.   PLoS One

Gene expression of Pseudomonas aeruginosa in a mucin-containing synthetic growth medium mimicking cystic fibrosis lung sputum

(2010) C. Fung et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances

(2008) Irith Wiegand et al.   Nature Protocols