Deep learning-based mixed-dimensional Gaussian mixture model for characterizing variability in cryo-EM

CryoDRGN: reconstruction of heterogeneous cryo-EM structures using neural networks

(2021) Ellen D. Zhong et al.   NATURE METHODS

3D variability analysis: Resolving continuous flexibility and discrete heterogeneity from single particle cryo-EM

(2021) Ali Punjani et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structures and distributions of SARS-CoV-2 spike proteins on intact virions

(2020) Zunlong Ke et al.   NATURE

Retrieving functional pathways of biomolecules from single-particle snapshots

(2020) Ali Dashti et al.   Nature Communications

Principles for Integrative Structural Biology Studies

(2019) Michael P. Rout et al.   CELL

Gaussian-input Gaussian mixture model for representing density maps and atomic models

(2018) Takeshi Kawabata   JOURNAL OF STRUCTURAL BIOLOGY

Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION

(2018) Takanori Nakane et al.   eLife

Integrative structure and functional anatomy of a nuclear pore complex

(2018) Seung Joong Kim et al.   NATURE

Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome

(2018) Yuanchen Dong et al.   NATURE

Bayesian Weighing of Electron Cryo-Microscopy Data for Integrative Structural Modeling

(2018) Massimiliano Bonomi et al.   STRUCTURE

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

Structure of a pre-catalytic spliceosome

(2017) Clemens Plaschka et al.   NATURE

Modular Assembly of the Bacterial Large Ribosomal Subunit

(2016) Joseph H. Davis et al.   CELL

Coarse-Graining of Volumes for Modeling of Structure and Dynamics in Electron Microscopy: Algorithm to Automatically Control Accuracy of Approximation

(2016) Slavica Jonic et al.   IEEE Journal of Selected Topics in Signal Processing

High resolution single particle refinement in EMAN2.1

(2016) James M. Bell et al.   METHODS

Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex

(2016) Tian-Min Fu et al.   MOLECULAR CELL

EMPIAR: a public archive for raw electron microscopy image data

(2016) Andrii Iudin et al.   NATURE METHODS

Three-dimensional structure of human γ-secretase

(2014) Peilong Lu et al.   NATURE

Identifying Conformational States of Macromolecules by Eigen-Analysis of Resampled Cryo-EM Images

(2011) Pawel A. Penczek et al.   STRUCTURE