A call for direct sequencing of full-length RNAs to identify all modifications

Editing and Chemical Modifications on Non-Coding RNAs in Cancer: A New Tale with Clinical Significance

(2021) Ligia I. Torsin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Analysis of RNA Modifications by Second- and Third-Generation Deep Sequencing: 2020 Update

(2021) Yuri Motorin et al.   Genes

Quantitative profiling of pseudouridylation dynamics in native RNAs with nanopore sequencing

(2021) Oguzhan Begik et al.   NATURE BIOTECHNOLOGY

Nanopore direct RNA sequencing maps the complexity of Arabidopsis mRNA processing and m6A modification

(2020) Matthew T Parker et al.   eLife

RNA Modifications in Health and Disease

(2020) Tsutomu Suzuki   FASEB JOURNAL

MasterOfPores: A Workflow for the Analysis of Oxford Nanopore Direct RNA Sequencing Datasets

(2020) Luca Cozzuto et al.   Frontiers in Genetics

Telomere-to-telomere assembly of a complete human X chromosome

(2020) Karen H. Miga et al.   NATURE

Decoding the epitranscriptional landscape from native RNA sequences

(2020) Piroon Jenjaroenpun et al.   NUCLEIC ACIDS RESEARCH

New Twists in Detecting mRNA Modification Dynamics

(2020) Ina Anreiter et al.   TRENDS IN BIOTECHNOLOGY

Molecular barcoding of native RNAs using nanopore sequencing and deep learning

(2020) Martin A. Smith et al.   GENOME RESEARCH

Current State of Oligonucleotide Characterization Using Liquid Chromatography–Mass Spectrometry: Insight into Critical Issues

(2020) J. Michael Sutton et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Determination of isoform-specific RNA structure with nanopore long reads

(2020) Jong Ghut Ashley Aw et al.   NATURE BIOTECHNOLOGY

Single-molecule sequencing detection of N6-methyladenine in microbial reference materials

(2019) Alexa B. R. McIntyre et al.   Nature Communications

Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution

(2019) Vahid Khoddami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using long-read sequencing to detect imprinted DNA methylation

(2019) Scott Gigante et al.   NUCLEIC ACIDS RESEARCH

DeepSignal: detecting DNA methylation state from Nanopore sequencing reads using deep-learning

(2019) Peng Ni et al.   BIOINFORMATICS

Disruption of RNA Metabolism in Neurological Diseases and Emerging Therapeutic Interventions

(2019) Julia K. Nussbacher et al.   NEURON

Accurate detection of m6A RNA modifications in native RNA sequences

(2019) Huanle Liu et al.   Nature Communications

Splicing Kinetics and Coordination Revealed by Direct Nascent RNA Sequencing through Nanopores

(2019) Heather L. Drexler et al.   MOLECULAR CELL

Nanopore sequencing and assembly of a human genome with ultra-long reads

(2018) Miten Jain et al.   NATURE BIOTECHNOLOGY

Highly parallel direct RNA sequencing on an array of nanopores

(2018) Daniel R Garalde et al.   NATURE METHODS

Base modifications affecting RNA polymerase and reverse transcriptase fidelity

(2018) Vladimir Potapov et al.   NUCLEIC ACIDS RESEARCH

Detecting DNA cytosine methylation using nanopore sequencing

(2017) Jared T Simpson et al.   NATURE METHODS

Mapping DNA methylation with high-throughput nanopore sequencing

(2017) Arthur C Rand et al.   NATURE METHODS

The RNA modification landscape in human disease

(2017) Nicky Jonkhout et al.   RNA

Efficient and quantitative high-throughput tRNA sequencing

(2015) Guanqun Zheng et al.   NATURE METHODS

Transcriptome-wide Mapping Reveals Widespread Dynamic-Regulated Pseudouridylation of ncRNA and mRNA

(2014) Schraga Schwartz et al.   CELL

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

(2012) Kate D. Meyer et al.   CELL

A General Population Genetic Framework for Antagonistic Selection That Accounts for Demography and Recurrent Mutation

(2012) T. Connallon et al.   GENETICS

Identification of epigenetic DNA modifications with a protein nanopore

(2010) Emma V. B. Wallace et al.   CHEMICAL COMMUNICATIONS

Nanopore DNA sequencing with MspA

(2010) I. M. Derrington et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Continuous base identification for single-molecule nanopore DNA sequencing

(2009) James Clarke et al.   Nature Nanotechnology