Identification of rare, transient post-mitotic cell states that are induced by injury and required for whole-body regeneration in Schmidtea mediterranea

Planarian Anatomy Ontology: a resource to connect data within and across experimental platforms

(2021) Stephanie H. Nowotarski et al.   DEVELOPMENT

Cell-type diversity and regionalized gene expression in the planarian intestine

(2020) David J Forsthoefel et al.   eLife

A planarian RPS3 homolog is critical to the modulation of planarian regeneration

(2019) Xina Cheng et al.   GENE

Single-cell transcriptomes of the regenerating intestine reveal a revival stem cell

(2019) Arshad Ayyaz et al.   NATURE

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Wnt and TGFβ coordinate growth and patterning to regulate size-dependent behaviour

(2019) Christopher P. Arnold et al.   NATURE

An adaptable chromosome preparation methodology for use in invertebrate research organisms

(2018) Longhua Guo et al.   BMC BIOLOGY

Prospectively Isolated Tetraspanin + Neoblasts Are Adult Pluripotent Stem Cells Underlying Planaria Regeneration

(2018) An Zeng et al.   CELL

Cellular, ultrastructural and molecular analyses of epidermal cell development in the planarian Schmidtea mediterranea

(2018) Li-Chun Cheng et al.   DEVELOPMENTAL BIOLOGY

Cell type transcriptome atlas for the planarianSchmidtea mediterranea

(2018) Christopher T. Fincher et al.   SCIENCE

Cell type atlas and lineage tree of a whole complex animal by single-cell transcriptomics

(2018) Mireya Plass et al.   SCIENCE

Single-cell profiling of the developing mouse brain and spinal cord with split-pool barcoding

(2018) Alexander B. Rosenberg et al.   SCIENCE

A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing

(2018) Deng Pan et al.   SCIENCE

Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration

(2018) Tobias Gerber et al.   SCIENCE

The Cellular and Molecular Basis for Planarian Regeneration

(2018) Peter W. Reddien   CELL

Dimensionality reduction for visualizing single-cell data using UMAP

(2018) Etienne Becht et al.   NATURE BIOTECHNOLOGY

The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma

(2017) Amrita M. Nargund et al.   Cell Reports

Embryonic origin of adult stem cells required for tissue homeostasis and regeneration

(2017) Erin L Davies et al.   eLife

Regulation and plasticity of intestinal stem cells during homeostasis and regeneration

(2016) Joep Beumer et al.   DEVELOPMENT

Pathogenic shifts in endogenous microbiota impede tissue regeneration via distinct activation of TAK1/MKK/p38

(2016) Christopher P Arnold et al.   eLife

The rise of the starlet sea anemone Nematostella vectensis as a model system to investigate development and regeneration

(2016) Michael J. Layden et al.   Wiley Interdisciplinary Reviews-Developmental Biology

A mex3 homolog is required for differentiation during planarian stem cell lineage development

(2015) Shu Jun Zhu et al.   eLife

Egr-5 is a post-mitotic regulator of planarian epidermal differentiation

(2015) Kimberly C Tu et al.   eLife

Cancer Immunotherapy by Targeting IDO1/TDO and Their Downstream Effectors

(2015) Michael Platten et al.   Frontiers in Immunology

Modulating the stem cell niche for tissue regeneration

(2014) Steven W Lane et al.   NATURE BIOTECHNOLOGY

Plasticity of epithelial stem cells in tissue regeneration

(2014) C. Blanpain et al.   SCIENCE

Beyond the Niche: Tissue-Level Coordination of Stem Cell Dynamics

(2013) Lucy Erin O'Brien et al.   Annual Review of Cell and Developmental Biology

In situ hybridization protocol for enhanced detection of gene expression in the planarian Schmidtea mediterranea

(2013) Ryan S King et al.   BMC DEVELOPMENTAL BIOLOGY

Robust cellular reprogramming occurs spontaneously during liver regeneration

(2013) K. Yanger et al.   GENES & DEVELOPMENT

Reactivating head regrowth in a regeneration-deficient planarian species

(2013) S.-Y. Liu et al.   NATURE

Restoration of anterior regeneration in a planarian with limited regenerative ability

(2013) James M. Sikes et al.   NATURE

Follistatin antagonizes Activin signaling and acts with Notum to direct planarian head regeneration

(2013) Rachel H. Roberts-Galbraith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The zebrafish as a model for complex tissue regeneration

(2013) Matthew Gemberling et al.   TRENDS IN GENETICS

Muscle Cells Provide Instructions for Planarian Regeneration

(2013) Jessica N. Witchley et al.   Cell Reports

Tissue absence initiates regeneration through Follistatin-mediated inhibition of Activin signaling

(2013) Michael A Gaviño et al.   eLife

Tryptophan Catabolism in Cancer: Beyond IDO and Tryptophan Depletion

(2012) M. Platten et al.   CANCER RESEARCH

Genetic Regulators of a Pluripotent Adult Stem Cell System in Planarians Identified by RNAi and Clonal Analysis

(2012) Daniel E. Wagner et al.   Cell Stem Cell

Amputation induces stem cell mobilization to sites of injury during planarian regeneration

(2012) O. C. Guedelhoefer et al.   DEVELOPMENT

Repeated, Long-Term Cycling of Putative Stem Cells between Niches in a Basal Chordate

(2012) Yuval Rinkevich et al.   DEVELOPMENTAL CELL

A molecular wound response program associated with regeneration initiation in planarians

(2012) D. Wenemoser et al.   GENES & DEVELOPMENT

cDNA cloning of heat shock protein 90 gene and protein expression pattern in response to heavy metal exposure and thermal stress in planarian Dugesia japonica

(2012) Ke-Xue Ma et al.   MOLECULAR BIOLOGY REPORTS

Skin shedding and tissue regeneration in African spiny mice (Acomys)

(2012) Ashley W. Seifert et al.   NATURE

The history and enduring contributions of planarians to the study of animal regeneration

(2012) Sarah A. Elliott et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Planarian Immobilization, Partial Irradiation, and Tissue Transplantation

(2012) Otto C. Guedelhoefer IV et al.   Jove-Journal of Visualized Experiments

Injury-induced activation of the MAPK/CREB pathway triggers apoptosis-induced compensatory proliferation in hydra head regeneration

(2011) Simona Chera et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Stem cell-based growth, regeneration, and remodeling of the planarian intestine

(2011) David J. Forsthoefel et al.   DEVELOPMENTAL BIOLOGY

Polarized notum Activation at Wounds Inhibits Wnt Function to Promote Planarian Head Regeneration

(2011) C. P. Petersen et al.   SCIENCE

Planarian regeneration involves distinct stem cell responses to wounds and tissue absence

(2010) Danielle Wenemoser et al.   DEVELOPMENTAL BIOLOGY

Expression of secreted Wnt pathway components reveals unexpected complexity of the planarian amputation response

(2010) Kyle A. Gurley et al.   DEVELOPMENTAL BIOLOGY

A functional genomic screen in planarians identifies novel regulators of germ cell development

(2010) Y. Wang et al.   GENES & DEVELOPMENT

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

(2010) Toshiro Sato et al.   NATURE

Apoptosis, Stem Cells, and Tissue Regeneration

(2010) A. Bergmann et al.   Science Signaling

Smed-Evi/Wntless is required for  -catenin-dependent and -independent processes during planarian regeneration

(2009) T. Adell et al.   DEVELOPMENT

Multiple Wnts are involved in Hydra organizer formation and regeneration

(2009) Tobias Lengfeld et al.   DEVELOPMENTAL BIOLOGY

Cells keep a memory of their tissue origin during axolotl limb regeneration

(2009) Martin Kragl et al.   NATURE

A wound-induced Wnt expression program controls planarian regeneration polarity

(2009) C. P. Petersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stem Cells and Niches: Mechanisms That Promote Stem Cell Maintenance throughout Life

(2008) Sean J. Morrison et al.   CELL

Molecular Analysis of Stem Cells and Their Descendants during Cell Turnover and Regeneration in the Planarian Schmidtea mediterranea

(2008) George T. Eisenhoffer et al.   Cell Stem Cell

The PIWI proteins SMEDWI-2 and SMEDWI-3 are required for stem cell function and piRNA expression in planarians

(2008) D. Palakodeti et al.   RNA