Cell type transcriptome atlas for the planarianSchmidtea mediterranea

Orthogonal muscle fibres have different instructive roles in planarian regeneration

(2017) M. Lucila Scimone et al.   NATURE

Comprehensive single-cell transcriptional profiling of a multicellular organism

(2017) Junyue Cao et al.   SCIENCE

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

(2016) I. Tirosh et al.   SCIENCE

Hedgehog signaling regulates gene expression in planarian glia

(2016) Irving E Wang et al.   eLife

A functional genomics screen in planarians reveals regulators of whole-brain regeneration

(2016) Rachel H Roberts-Galbraith et al.   eLife

Light-induced depigmentation in planarians models the pathophysiology of acute porphyrias

(2016) Bradford M Stubenhaus et al.   eLife

Two FGFRL-Wnt circuits organize the planarian anteroposterior axis

(2016) M Lucila Scimone et al.   eLife

Evolution of the EGFR pathway in Metazoa and its diversification in the planarian Schmidtea mediterranea

(2016) Sara Barberán et al.   Scientific Reports

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Spiralian Phylogeny Informs the Evolution of Microscopic Lineages

(2015) Christopher E. Laumer et al.   CURRENT BIOLOGY

Wnt/Notum spatial feedback inhibition controls neoblast differentiation to regulate reversible growth of the planarian brain

(2015) E. M. Hill et al.   DEVELOPMENT

A Generic and Cell-Type-Specific Wound Response Precedes Regeneration in Planarians

(2015) Omri Wurtzel et al.   DEVELOPMENTAL CELL

Spatial reconstruction of single-cell gene expression data

(2015) Rahul Satija et al.   NATURE BIOTECHNOLOGY

Stem cells and fluid flow drive cyst formation in an invertebrate excretory organ

(2015) Hanh Thi-Kim Vu et al.   eLife

A mex3 homolog is required for differentiation during planarian stem cell lineage development

(2015) Shu Jun Zhu et al.   eLife

Egr-5 is a post-mitotic regulator of planarian epidermal differentiation

(2015) Kimberly C Tu et al.   eLife

Single-Cell Analysis Reveals Functionally Distinct Classes within the Planarian Stem Cell Compartment

(2014) Josien C. van Wolfswinkel et al.   Cell Stem Cell

Stem cell-dependent formation of a functional anterior regeneration pole in planarians requires Zic and Forkhead transcription factors

(2014) Matthias C. Vogg et al.   DEVELOPMENTAL BIOLOGY

Single-cell RNA-seq reveals dynamic paracrine control of cellular variation

(2014) Alex K. Shalek et al.   NATURE

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Bayesian approach to single-cell differential expression analysis

(2014) Peter V Kharchenko et al.   NATURE METHODS

Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types

(2014) D. A. Jaitin et al.   SCIENCE

A forkhead Transcription Factor Is Wound-Induced at the Planarian Midline and Required for Anterior Pole Regeneration

(2014) M. Lucila Scimone et al.   PLoS Genetics

zic-1 Expression in Planarian Neoblasts after Injury Controls Anterior Pole Regeneration

(2014) Constanza Vásquez-Doorman et al.   PLoS Genetics

Selective amputation of the pharynx identifies a FoxA-dependent regeneration program in planaria

(2014) Carolyn E Adler et al.   eLife

Neoblast Specialization in Regeneration of the Planarian Schmidtea mediterranea

(2014) M. Lucila Scimone et al.   Stem Cell Reports

In situ hybridization protocol for enhanced detection of gene expression in the planarian Schmidtea mediterranea

(2013) Ryan S King et al.   BMC DEVELOPMENTAL BIOLOGY

Specialized progenitors and regeneration

(2013) P. W. Reddien   DEVELOPMENT

A Pitx transcription factor controls the establishment and maintenance of the serotonergic lineage in planarians

(2013) M. Marz et al.   DEVELOPMENT

RNA interference by feeding in vitro-synthesized double-stranded RNA to planarians: Methodology and dynamics

(2013) Labib Rouhana et al.   DEVELOPMENTAL DYNAMICS

Reactivating head regrowth in a regeneration-deficient planarian species

(2013) S.-Y. Liu et al.   NATURE

Muscle Cells Provide Instructions for Planarian Regeneration

(2013) Jessica N. Witchley et al.   Cell Reports

Data exploration, quality control and testing in single-cell qPCR-based gene expression experiments

(2012) Andrew McDavid et al.   BIOINFORMATICS

Genetic Regulators of a Pluripotent Adult Stem Cell System in Planarians Identified by RNAi and Clonal Analysis

(2012) Daniel E. Wagner et al.   Cell Stem Cell

PRMT5 and the role of symmetrical dimethylarginine in chromatoid bodies of planarian stem cells

(2012) L. Rouhana et al.   DEVELOPMENT

An RNAi Screen Reveals Intestinal Regulators of Branching Morphogenesis, Differentiation, and Stem Cell Proliferation in Planarians

(2012) David J. Forsthoefel et al.   DEVELOPMENTAL CELL

Centrosome Loss in the Evolution of Planarians

(2012) J. Azimzadeh et al.   SCIENCE

Transcriptome Analysis of the Planarian Eye Identifies ovo as a Specific Regulator of Eye Regeneration

(2012) Sylvain W. Lapan et al.   Cell Reports

Noggin and Noggin-Like Genes Control Dorsoventral Axis Regeneration in Planarians

(2011) M. Dolores Molina et al.   CURRENT BIOLOGY

A Bmp/Admp Regulatory Circuit Controls Maintenance and Regeneration of Dorsal-Ventral Polarity in Planarians

(2011) Michael A. Gaviño et al.   CURRENT BIOLOGY

The maintenance and regeneration of the planarian excretory system are regulated by EGFR signaling

(2011) J. C. Rink et al.   DEVELOPMENT

A regulatory program for excretory system regeneration in planarians

(2011) M. L. Scimone et al.   DEVELOPMENT

Clonogenic Neoblasts Are Pluripotent Adult Stem Cells That Underlie Planarian Regeneration

(2011) D. E. Wagner et al.   SCIENCE

Polarized notum Activation at Wounds Inhibits Wnt Function to Promote Planarian Head Regeneration

(2011) C. P. Petersen et al.   SCIENCE

Constitutive gene expression and the specification of tissue identity in adult planarian biology

(2011) Peter W. Reddien   TRENDS IN GENETICS

dlx and sp6-9 Control Optic Cup Regeneration in a Prototypic Eye

(2011) Sylvain W. Lapan et al.   PLoS Genetics

Planarian regeneration involves distinct stem cell responses to wounds and tissue absence

(2010) Danielle Wenemoser et al.   DEVELOPMENTAL BIOLOGY

Expression of secreted Wnt pathway components reveals unexpected complexity of the planarian amputation response

(2010) Kyle A. Gurley et al.   DEVELOPMENTAL BIOLOGY

The use of lectins as markers for differentiated secretory cells in planarians

(2010) Ricardo M. Zayas et al.   DEVELOPMENTAL DYNAMICS

Analysis of motor function modulated by cholinergic neurons in planarian dugesia japonica

(2010) K. Nishimura et al.   NEUROSCIENCE

Genome-Wide Analyses Reveal a Role for Peptide Hormones in Planarian Germline Development

(2010) James J. Collins et al.   PLOS BIOLOGY

The TALE Class Homeobox Gene Smed-prep Defines the Anterior Compartment for Head Regeneration

(2010) Daniel A. Felix et al.   PLoS Genetics

BLAST+: architecture and applications

(2009) Christiam Camacho et al.   BMC BIOINFORMATICS

Smed-Evi/Wntless is required for  -catenin-dependent and -independent processes during planarian regeneration

(2009) T. Adell et al.   DEVELOPMENT

Expression pattern of the expanded noggin gene family in the planarian Schmidtea mediterranea

(2009) Ma Dolores Molina et al.   GENE EXPRESSION PATTERNS

A wound-induced Wnt expression program controls planarian regeneration polarity

(2009) C. P. Petersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Planarian Hh Signaling Regulates Regeneration Polarity and Links Hh Pathway Evolution to Cilia

(2009) J. C. Rink et al.   SCIENCE

Molecular Analysis of Stem Cells and Their Descendants during Cell Turnover and Regeneration in the Planarian Schmidtea mediterranea

(2008) George T. Eisenhoffer et al.   Cell Stem Cell

Characterization of tyramine β-hydroxylase in planarian Dugesia japonica: Cloning and expression

(2008) Kaneyasu Nishimura et al.   NEUROCHEMISTRY INTERNATIONAL

Identification of glutamic acid decarboxylase gene and distribution of GABAergic nervous system in the planarian Dugesia japonica

(2008) K. Nishimura et al.   NEUROSCIENCE

 -Catenin Defines Head Versus Tail Identity During Planarian Regeneration and Homeostasis

(2007) K. A. Gurley et al.   SCIENCE

Smed- catenin-1 Is Required for Anteroposterior Blastema Polarity in Planarian Regeneration

(2007) C. P. Petersen et al.   SCIENCE