Apc-mutant cells act as supercompetitors in intestinal tumour initiation

NOTUM from Apc-mutant cells biases clonal competition to initiate cancer

(2021) Dustin J. Flanagan et al.   NATURE

Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance

(2020) Till Ringel et al.   Cell Stem Cell

Stem cell competition orchestrates skin homeostasis and ageing

(2019) Nan Liu et al.   NATURE

Distinct modes of cell competition shape mammalian tissue morphogenesis

(2019) Stephanie J. Ellis et al.   NATURE

Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium

(2019) Nalle Pentinmikko et al.   NATURE

A cancer rainbow mouse for visualizing the functional genomics of oncogenic clonal expansion

(2019) Peter G. Boone et al.   Nature Communications

Stan: A Probabilistic Programming Language

(2017) Bob Carpenter et al.   Journal of Statistical Software

QuPath: Open source software for digital pathology image analysis

(2017) Peter Bankhead et al.   Scientific Reports

Lithium treatment and cancer incidence in bipolar disorder

(2016) Lina Martinsson et al.   BIPOLAR DISORDERS

Use of lithium and cancer risk in patients with bipolar disorder: population-based cohort study

(2016) Ru-Yu Huang et al.   BRITISH JOURNAL OF PSYCHIATRY

Cell Competition Drives the Growth of Intestinal Adenomas in Drosophila

(2016) Saskia J.E. Suijkerbuijk et al.   CURRENT BIOLOGY

TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype

(2016) Evelyn Fessler et al.   EMBO Molecular Medicine

Bcl-2 is a critical mediator of intestinal transformation

(2016) Maartje van der Heijden et al.   Nature Communications

Notum deacylates Wnt proteins to suppress signalling activity

(2015) Satoshi Kakugawa et al.   NATURE

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Novel insights into Notum and glypicans regulation in colorectal cancer

(2015) Mariangela De Robertis et al.   Oncotarget

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Easy quantitative assessment of genome editing by sequence trace decomposition

(2014) Eva K. Brinkman et al.   NUCLEIC ACIDS RESEARCH

Biased competition between Lgr5 intestinal stem cells driven by oncogenic mutation induces clonal expansion

(2013) Hugo J. Snippert et al.   EMBO REPORTS

Defining Stem Cell Dynamics in Models of Intestinal Tumor Initiation

(2013) L. Vermeulen et al.   SCIENCE

The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers

(2012) Javier Muñoz et al.   EMBO JOURNAL

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors

(2012) Bon-Kyoung Koo et al.   NATURE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse

(2011) Anna Merlos-Suárez et al.   Cell Stem Cell

Steep Differences in Wingless Signaling Trigger Myc-Independent Competitive Cell Interactions

(2011) Jean-Paul Vincent et al.   DEVELOPMENTAL CELL

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

Intestinal Stem Cell Replacement Follows a Pattern of Neutral Drift

(2010) C. Lopez-Garcia et al.   SCIENCE

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Differentiation-Defective Stem Cells Outcompete Normal Stem Cells for Niche Occupancy in the Drosophila Ovary

(2008) Zhigang Jin et al.   Cell Stem Cell