2021: an immunotherapy odyssey and the rise of nucleic acid nanotechnology

The fate of nanoparticles in vivo and the strategy of designing stealth nanoparticle for drug delivery

(2021) Jianwei Bao et al.   CURRENT DRUG TARGETS

Food and Drug Administration Beyond the 2001 Government Accountability Office Report: Promoting Drug Safety for Women

(2021) Marjorie R. Jenkins et al.   JOURNAL OF WOMENS HEALTH

Induction of Cytokines by Nucleic Acid Nanoparticles (NANPs) Depends on the Type of Delivery Carrier

(2021) Yelixza I. Avila et al.   MOLECULES

Opportunities, Barriers, and a Strategy for Overcoming Translational Challenges to Therapeutic Nucleic Acid Nanotechnology

(2020) Kirill A. Afonin et al.   ACS Nano

Recent advances in mRNA vaccine technology

(2020) Norbert Pardi et al.   CURRENT OPINION IN IMMUNOLOGY

A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice

(2020) Dorottya Laczkó et al.   IMMUNITY

SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness

(2020) Kizzmekia S. Corbett et al.   NATURE

Opportunities and challenges for the clinical translation of structured DNA assemblies as gene therapeutic delivery and vaccine vectors

(2020) Marina A. Dobrovolskaia et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses

(2020) Ugur Sahin et al.   NATURE

The immunorecognition, subcellular compartmentalization, and physicochemical properties of nucleic acid nanoparticles can be controlled by composition modification

(2020) Morgan Brittany Johnson et al.   NUCLEIC ACIDS RESEARCH

Toll-Like Receptor-Mediated Recognition of Nucleic Acid Nanoparticles (NANPs) in Human Primary Blood Cells

(2019) Enping Hong et al.   MOLECULES

Aptamers as Modular Components of Therapeutic Nucleic Acid Nanotechnology

(2019) Martin Panigaj et al.   ACS Nano

Nucleic Acid Nanoparticles at a Crossroads of Vaccines and Immunotherapies

(2019) Marina A. Dobrovolskaia   MOLECULES

Orthogonal Protein-Responsive mRNA Switches for Mammalian Synthetic Biology

(2019) Hiroki Ono et al.   ACS Synthetic Biology

Improved Nucleic Acid Therapy with Advanced Nanoscale Biotechnology

(2019) Yuhua Weng et al.   Molecular Therapy-Nucleic Acids

Innate immune responses triggered by nucleic acids inspire the design of immunomodulatory nucleic acid nanoparticles (NANPs)

(2019) Morgan Chandler et al.   CURRENT OPINION IN BIOTECHNOLOGY

Structure and Composition Define Immunorecognition of Nucleic Acid Nanoparticles

(2018) Enping Hong et al.   NANO LETTERS

Recognition of Endogenous Nucleic Acids by the Innate Immune System

(2016) Axel Roers et al.   IMMUNITY

Multifunctional RNA Nanoparticles

(2014) Kirill A. Afonin et al.   NANO LETTERS

mRNA-based therapeutics — developing a new class of drugs

(2014) Ugur Sahin et al.   NATURE REVIEWS DRUG DISCOVERY

Organization of Intracellular Reactions with Rationally Designed RNA Assemblies

(2011) C. J. Delebecque et al.   SCIENCE