Polyplex nanovesicles of single strand oligonucleotides for efficient cytosolic delivery of biomacromolecules

The delivery challenge: fulfilling the promise of therapeutic genome editing

(2020) Joost van Haasteren et al.   NATURE BIOTECHNOLOGY

Overcoming negatively charged tissue barriers: Drug delivery using cationic peptides and proteins

(2020) Armin Vedadghavami et al.   Nano Today

Stimulus-responsive sequential release systems for drug and gene delivery

(2020) Sepideh Ahmadi et al.   Nano Today

The current state and future directions of RNAi-based therapeutics

(2019) Ryan L. Setten et al.   NATURE REVIEWS DRUG DISCOVERY

Self-Assembly of siRNA/PEG-b-Catiomer at Integer Molar Ratio into 100 nm-Sized Vesicular Polyion Complexes (siRNAsomes) for RNAi and Codelivery of Cargo Macromolecules

(2019) Beob Soo Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stressing the Role of DNA as a Drug Carrier: Synthesis of DNA-Drug Conjugates through Grafting Chemotherapeutics onto Phosphorothioate Oligonucleotides

(2019) Yuanyuan Guo et al.   ADVANCED MATERIALS

RNAi therapeutic and its innovative biotechnological evolution

(2019) Yuhua Weng et al.   BIOTECHNOLOGY ADVANCES

Enzyme-activatable polymer–drug conjugate augments tumour penetration and treatment efficacy

(2019) Quan Zhou et al.   Nature Nanotechnology

A boronic acid–rich dendrimer with robust and unprecedented efficiency for cytosolic protein delivery and CRISPR-Cas9 gene editing

(2019) Chongyi Liu et al.   Science Advances

Rational Design of Nanocarriers for Intracellular Protein Delivery

(2019) Xiaofei Qin et al.   ADVANCED MATERIALS

A biodegradable nanocapsule delivers a Cas9 ribonucleoprotein complex for in vivo genome editing

(2019) Guojun Chen et al.   Nature Nanotechnology

Engineered materials for in vivo delivery of genome-editing machinery

(2019) Sheng Tong et al.   Nature Reviews Materials

Substrate-Sorting Nanoreactors Based on Permeable Peptide Polymer Vesicles and Hybrid Liposomes with Synthetic Macromolecular Channels

(2019) Tomoki Nishimura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Gene Therapy Arrives

(2019) Jim Daley   NATURE

Protein delivery into cells using inorganic nanoparticle–protein supramolecular assemblies

(2018) Federica Scaletti et al.   CHEMICAL SOCIETY REVIEWS

The fluorination effect of fluoroamphiphiles in cytosolic protein delivery

(2018) Zhenjing Zhang et al.   Nature Communications

Green Tea Catechin Dramatically Promotes RNAi Mediated by Low-Molecular-Weight Polymers

(2018) Wanwan Shen et al.   ACS Central Science

Integrating Combinatorial Lipid Nanoparticle and Chemically Modified Protein for Intracellular Delivery and Genome Editing

(2018) Jin Chang et al.   ACCOUNTS OF CHEMICAL RESEARCH

RNA Micelles for the Systemic Delivery of Anti-miRNA for Cancer Targeting and Inhibition without Ligand

(2018) Hongran Yin et al.   ACS Nano

Active Targeting of the Nucleus Using Nonpeptidic Boronate Tags

(2017) Rui Tang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rational Design of a Polymer with Robust Efficacy for Intracellular Protein and Peptide Delivery

(2017) Hong Chang et al.   NANO LETTERS

Cytosolic antibody delivery by lipid-sensitive endosomolytic peptide

(2017) Misao Akishiba et al.   Nature Chemistry

The applications of the novel polymeric fluoropyrimidine F10 in cancer treatment: current evidence

(2016) William H Gmeiner et al.   Future Oncology

Influence of RNA Strand Rigidity on Polyion Complex Formation with Block Catiomers

(2016) Kotaro Hayashi et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Multivalent Polymer Nanocomplex Targeting Endosomal Receptor of Immune Cells for Enhanced Antitumor and Systemic Memory Response

(2015) Sun-Young Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aptamer Oligonucleotides: Novel Potential Therapeutic Agents in Autoimmune Disease

(2015) Weibin Li et al.   Nucleic Acid Therapeutics

Reactive Oxygen Species-Responsive Protein Modification and Its Intracellular Delivery for Targeted Cancer Therapy

(2014) Ming Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Combinatorially Designed Lipid-like Nanoparticles for Intracellular Delivery of Cytotoxic Protein for Cancer Therapy

(2014) Ming Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fabrication of Polyion Complex Vesicles with Enhanced Salt and Temperature Resistance and Their Potential Applications as Enzymatic Nanoreactors

(2014) Sayan Chuanoi et al.   BIOMACROMOLECULES

Intracellular delivery of functionally active proteins using self-assembling pyridylthiourea-polyethylenimine

(2014) Viktoriia Postupalenko et al.   JOURNAL OF CONTROLLED RELEASE

Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

(2014) John A Zuris et al.   NATURE BIOTECHNOLOGY

Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies

(2014) Samir Mitragotri et al.   NATURE REVIEWS DRUG DISCOVERY

Recent progress of cell-penetrating peptides as new carriers for intracellular cargo delivery

(2013) Feihu Wang et al.   JOURNAL OF CONTROLLED RELEASE

Structural factors directing nanosized polyion complex vesicles (Nano-PICsomes) to form a pair of block aniomer/homo catiomers: studies on the aniomer segment length and the catiomer side-chain structure

(2013) Sayan Chuanoi et al.   POLYMER JOURNAL

Saporin-S6: A Useful Tool in Cancer Therapy

(2013) Letizia Polito et al.   Toxins

A human ribonuclease induces apoptosis associated with p21WAF1/CIP1induction and JNK inactivation

(2011) Jessica Castro et al.   BMC CANCER

Tailoring nanocarriers for intracellular protein delivery

(2011) Zhen Gu et al.   CHEMICAL SOCIETY REVIEWS

Recognition of Single- and Double-Stranded Oligonucleotides by Bovine Serum Albumin via Nonspecific Interactions

(2010) Yuqiong Xia et al.   BIOMACROMOLECULES

Preparation and characterization of sodium ferulate entrapped bovine serum albumin nanoparticles for liver targeting

(2007) Feng-Qian Li et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS