Ferroptosis-Strengthened Metabolic and Inflammatory Regulation of Tumor-Associated Macrophages Provokes Potent Tumoricidal Activities

A Metal‐Organic Framework (MOF) Fenton Nanoagent‐Enabled Nanocatalytic Cancer Therapy in Synergy with Autophagy Inhibition

(2020) Bowen Yang et al.   ADVANCED MATERIALS

Tumor associated macrophages and ‘NO’

(2020) Niharika Nath et al.   BIOCHEMICAL PHARMACOLOGY

Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death

(2020) Alexandr A. Kapralov et al.   Nature Chemical Biology

Evaluating the Polarization of Tumor-Associated Macrophages Into M1 and M2 Phenotypes in Human Cancer Tissue: Technicalities and Challenges in Routine Clinical Practice

(2020) Sharmilla Devi Jayasingam et al.   Frontiers in Oncology

Metal–Organic Framework Nanoparticles Induce Pyroptosis in Cells Controlled by the Extracellular pH

(2020) Evelyn Ploetz et al.   ADVANCED MATERIALS

A Tumor-Targeted Cascade Nanoreactor Based on Metal-Organic-Frameworks for Synergistic Ferroptosis−Starvation Anticancer Therapy

(2020) Xiuyan Wan et al.   ACS Nano

Mitochondrial Electron Transport: Oxidative Phosphorylation, Mitochondrial Oxidant Production, and Methods of Measurement

(2020) Deirdre Nolfi-Donegan et al.   Redox Biology

Engineering Macrophages for Cancer Immunotherapy and Drug Delivery

(2020) Yuqiong Xia et al.   ADVANCED MATERIALS

Breast cancer–associated macrophages promote tumorigenesis by suppressing succinate dehydrogenase in tumor cells

(2020) Valentí Gómez et al.   Science Signaling

Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47−mediated ‘don’t-eat-me’ signal

(2019) Mingen Liu et al.   NATURE IMMUNOLOGY

Tailoring Nanomaterials for Targeting Tumor‐Associated Macrophages

(2019) Muhammad Ovais et al.   ADVANCED MATERIALS

Mechanism of Iron Oxide-Induced Macrophage Activation: The Impact of Composition and the Underlying Signaling Pathway

(2019) Zhengying Gu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Generation of monocyte-derived tumor-associated macrophages using tumor-conditioned media provides a novel method to study tumor-associated macrophages in vitro

(2019) Brooke Benner et al.   Journal for ImmunoTherapy of Cancer

Macrophages and Metabolism in the Tumor Microenvironment

(2019) Ilio Vitale et al.   Cell Metabolism

Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS–) vs. Alternatively Activated Macrophages

(2019) Marco Orecchioni et al.   Frontiers in Immunology

Metadherin enhances vulnerability of cancer cells to ferroptosis

(2019) Jianling Bi et al.   Cell Death & Disease

Amorphous Metal-Organic Framework-Dominated Nanocomposites with Both Compositional and Structural Heterogeneity for Oxygen Evolution

(2019) Chao Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

GPx4, Lipid Peroxidation, and Cell Death: Discoveries, Rediscoveries, and Open Issues

(2018) Matilde Maiorino et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial DNA damage and reactive oxygen species in neurodegenerative disease

(2018) Nadee Nissanka et al.   FEBS LETTERS

Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration

(2018) Moataz Abdalkader et al.   Frontiers in Neuroscience

Metal-organic frameworks, NH2-MIL-88(Fe), as carriers for ophthalmic delivery of brimonidine

(2018) Se-Na Kim et al.   Acta Biomaterialia

Targeting macrophages: therapeutic approaches in cancer

(2018) Luca Cassetta et al.   NATURE REVIEWS DRUG DISCOVERY

Macrophages as Key Drivers of Cancer Progression and Metastasis

(2017) Sebastian R. Nielsen et al.   MEDIATORS OF INFLAMMATION

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

Macrophage Immunometabolism: Where Are We (Going)?

(2017) Jan Van den Bossche et al.   TRENDS IN IMMUNOLOGY

Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis

(2016) Mathias Wenes et al.   Cell Metabolism

Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation

(2016) Vicky Lampropoulou et al.   Cell Metabolism

Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages

(2016) Jan Van den Bossche et al.   Cell Reports

Is Synovial Macrophage Activation the Inflammatory Link Between Obesity and Osteoarthritis?

(2016) Antonia RuJia Sun et al.   Current Rheumatology Reports

Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation

(2016) Anthony J Covarrubias et al.   eLife

Metabolic Reprogramming of Immune Cells in Cancer Progression

(2015) Subhra K. Biswas   IMMUNITY

Macrophage iron homeostasis and polarization in the context of cancer

(2015) Michaela Jung et al.   IMMUNOBIOLOGY

Metabolic Characterization of Polarized M1 and M2 Bone Marrow-derived Macrophages Using Real-time Extracellular Flux Analysis

(2015) Jan Van den Bossche et al.   Jove-Journal of Visualized Experiments

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance

(2014) Nan Wang et al.   Frontiers in Immunology

Mammalian Iron Homeostasis in Health and Disease: Uptake, Storage, Transport, and Molecular Mechanisms of Action

(2012) Alfons Lawen et al.   ANTIOXIDANTS & REDOX SIGNALING

The Two Faces of Interferon-  in Cancer

(2011) M. R. Zaidi et al.   CLINICAL CANCER RESEARCH

Regulators of macrophage activation

(2011) Fernando O. Martinez   EUROPEAN JOURNAL OF IMMUNOLOGY

Novel Route to Size-Controlled Fe–MIL-88B–NH2Metal–Organic Framework Nanocrystals

(2011) Minh-Hao Pham et al.   LANGMUIR

Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C(high) Monocytes

(2010) K. Movahedi et al.   CANCER RESEARCH