Calcium signaling mediates a biphasic mechanoadaptive response of endothelial cells to cyclic mechanical stretch

Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage

(2020) Michele M. Nava et al.   CELL

Endothelial cell Piezo1 mediates pressure-induced lung vascular hyperpermeability via disruption of adherens junctions

(2019) Emily E. Friedrich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Force Sensing by Piezo Channels in Cardiovascular Health and Disease

(2019) David J. Beech et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Structural Biology: Piezo Senses Tension through Curvature

(2018) Xin Liang et al.   CURRENT BIOLOGY

Tensile Forces and Mechanotransduction at Cell–Cell Junctions

(2018) Guillaume Charras et al.   CURRENT BIOLOGY

Septins regulate junctional integrity of endothelial monolayers

(2018) Joanna Kim et al.   MOLECULAR BIOLOGY OF THE CELL

Piezo1 and Gq/G11 promote endothelial inflammation depending on flow pattern and integrin activation

(2018) Julián Albarrán-Juárez et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mechanical Force-Driven Adherens Junction Remodeling and Epithelial Dynamics

(2018) Diana Pinheiro et al.   DEVELOPMENTAL CELL

A Mechanosensitive RhoA Pathway that Protects Epithelia against Acute Tensile Stress

(2018) Bipul R. Acharya et al.   DEVELOPMENTAL CELL

Adhesion forces and cortical tension couple cell proliferation and differentiation to drive epidermal stratification

(2017) Yekaterina A. Miroshnikova et al.   NATURE CELL BIOLOGY

Actin cortex architecture regulates cell surface tension

(2017) Priyamvada Chugh et al.   NATURE CELL BIOLOGY

Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance

(2017) Baptiste Rode et al.   Nature Communications

Cell–cell junctional mechanotransduction in endothelial remodeling

(2016) Yvonne L. Dorland et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

EpiTools: An Open-Source Image Analysis Toolkit for Quantifying Epithelial Growth Dynamics

(2016) Davide Heller et al.   DEVELOPMENTAL CELL

Biomechanics of vascular mechanosensation and remodeling

(2016) Nicolas Baeyens et al.   MOLECULAR BIOLOGY OF THE CELL

Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension

(2016) Charles D. Cox et al.   Nature Communications

A comparison of fluorescent Ca2+ indicators for imaging local Ca2+ signals in cultured cells

(2015) Jeffrey T. Lock et al.   CELL CALCIUM

Rac1 functions as a reversible tension modulator to stabilize VE-cadherin trans-interaction

(2015) Nazila Daneshjou et al.   JOURNAL OF CELL BIOLOGY

Cadherin Adhesion and Mechanotransduction

(2014) D.E. Leckband et al.   Annual Review of Cell and Developmental Biology

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

Appreciating force and shape — the rise of mechanotransduction in cell biology

(2014) Thomas Iskratsch et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rho GAPs and GEFs

(2014) Jaap D van Buul et al.   Cell Adhesion & Migration

A systems biology view of blood vessel growth and remodelling

(2013) Elizabeth A. Logsdon et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

α-catenin, vinculin, and F-actin in strengthening E-cadherin cell–cell adhesions and mechanosensing

(2013) Sylvie Dufour et al.   Cell Adhesion & Migration

Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling

(2012) Stephan Huveneers et al.   JOURNAL OF CELL BIOLOGY

Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia

(2012) George T. Eisenhoffer et al.   NATURE

Icy: an open bioimage informatics platform for extended reproducible research

(2012) Fabrice de Chaumont et al.   NATURE METHODS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Vinculin-dependent Cadherin mechanosensing regulates efficient epithelial barrier formation

(2012) F. Twiss et al.   Biology Open

The Mechanosensitive Ion Channel Piezo1 Is Inhibited by the Peptide GsMTx4

(2011) Chilman Bae et al.   BIOCHEMISTRY

A tension-induced mechanotransduction pathway promotes epithelial morphogenesis

(2011) Huimin Zhang et al.   NATURE

Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A

(2011) A. J. Ehrlicher et al.   NATURE

Dynamic molecular processes mediate cellular mechanotransduction

(2011) Brenton D. Hoffman et al.   NATURE

Substrate stiffening promotes endothelial monolayer disruption through enhanced physical forces

(2010) Ramaswamy Krishnan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Molecular Pathway and Cell State Responsible for Dissociation-Induced Apoptosis in Human Pluripotent Stem Cells

(2010) Masatoshi Ohgushi et al.   Cell Stem Cell

Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II–dependent manner

(2010) Quint le Duc et al.   JOURNAL OF CELL BIOLOGY

α-Catenin as a tension transducer that induces adherens junction development

(2010) Shigenobu Yonemura et al.   NATURE CELL BIOLOGY

Filamin A Is Essential for Active Cell Stiffening but not Passive Stiffening under External Force

(2009) K.E. Kasza et al.   BIOPHYSICAL JOURNAL

PAK is required for the disruption of E-cadherin adhesion by the small GTPase Rac

(2008) E. Lozano et al.   JOURNAL OF CELL SCIENCE

Mechanotransduction in vascular physiology and atherogenesis

(2008) Cornelia Hahn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY