Regulatory T cells promote the stemness of leukemia stem cells through IL10 cytokine-related signaling pathway

IL-10 derived from M2 macrophage promotes cancer stemness via JAK1/STAT1/NF-κB/Notch1 pathway in non-small cell lung cancer

(2019) Li Yang et al.   INTERNATIONAL JOURNAL OF CANCER

Role of OCT4 in cancer stem-like cells and chemotherapy resistance

(2019) Ismail S. Mohiuddin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Blocking migration of regulatory T cells to leukemic hematopoietic microenvironment delays disease progression in mouse leukemia model

(2019) Rong Wang et al.   CANCER LETTERS

The IGF2/IGF1R/Nanog Signaling Pathway Regulates the Proliferation of Acute Myeloid Leukemia Stem Cells

(2018) Dan-dan Xu et al.   Frontiers in Pharmacology

The stem cell-associated gene expression signature allows risk stratification in pediatric acute myeloid leukemia

(2018) Nicolas Duployez et al.   LEUKEMIA

Acute Myeloid Leukemia Cells Express ICOS Ligand to Promote the Expansion of Regulatory T Cells

(2018) Yixiang Han et al.   Frontiers in Immunology

Second cycle remission achievement with 7+3 and survival in adults with newly diagnosed acute myeloid leukemia: analysis of recent SWOG trials

(2018) Megan Othus et al.   LEUKEMIA

Sox2 Communicates with Tregs Through CCL1 to Promote the Stemness Property of Breast Cancer Cells

(2017) Yingxi Xu et al.   STEM CELLS

Expression of embryonic stem cell markers in acute myeloid leukemia

(2017) Tiphanie Picot et al.   TUMOR BIOLOGY

Acquired expression of osteopontin selectively promotes enrichment of leukemia stem cells through AKT/mTOR/PTEN/β-catenin pathways in AML cells

(2016) Saeed Mohammadi et al.   LIFE SCIENCES

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

Regulatory T cells-derived IL-35 promotes the growth of adult acute myeloid leukemia blasts

(2015) Qianshan Tao et al.   INTERNATIONAL JOURNAL OF CANCER

IL10 receptor is a novel therapeutic target in DLBCLs

(2015) W Béguelin et al.   LEUKEMIA

Acute Myeloid Leukemia

(2015) Hartmut Döhner et al.   NEW ENGLAND JOURNAL OF MEDICINE

Concise Review: NANOG in Cancer Stem Cells and Tumor Development: An Update and Outstanding Questions

(2015) Collene R. Jeter et al.   STEM CELLS

High expression of OCT4 is frequent and may cause undesirable treatment outcomes in patients with acute myeloid leukemia

(2015) Jia-Yu Yin et al.   TUMOR BIOLOGY

A network map of Interleukin-10 signaling pathway

(2015) Renu Verma et al.   Journal of Cell Communication and Signaling

Bone marrow stromal cells protect acute myeloid leukemia cells from anti-CD44 therapy partly through regulating PI3K/Akt-p27Kip1axis

(2014) Ping Chen et al.   MOLECULAR CARCINOGENESIS

Inactivation of PTEN increases ABCG2 expression and the side population through the PI3K/Akt pathway in adult acute leukemia

(2013) Fang-Fang Huang et al.   CANCER LETTERS

CD82 regulates STAT5/IL-10 and supports survival of acute myelogenous leukemia cells

(2013) Chie Nishioka et al.   INTERNATIONAL JOURNAL OF CANCER

Clinical significance of Treg cell frequency in acute myeloid leukemia

(2013) Wenjuan Yang et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

AKT collaborates with ERG and Gata1s to dysregulate megakaryopoiesis and promote AMKL

(2013) M J Stankiewicz et al.   LEUKEMIA

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Current treatment of acute myeloid leukemia

(2012) Gail J. Roboz   CURRENT OPINION IN ONCOLOGY

The immunosuppressive tumour network: myeloid-derived suppressor cells, regulatory T cells and natural killer T cells

(2012) Dennis Lindau et al.   IMMUNOLOGY

Increased CD200 expression in acute myeloid leukemia is linked with an increased frequency of FoxP3+ regulatory T cells

(2012) S J Coles et al.   LEUKEMIA

Reciprocal Regulation of Akt and Oct4 Promotes the Self-Renewal and Survival of Embryonal Carcinoma Cells

(2012) Yuanji Lin et al.   MOLECULAR CELL

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Regulatory T cells in acute myelogenous leukemia: is it time for immunomodulation?

(2011) C. Ustun et al.   BLOOD

In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche

(2011) Joji Fujisaki et al.   NATURE

Hematopoietic progenitor cell regulation by CD4+CD25+ T cells

(2010) M. Urbieta et al.   BLOOD

Indoleamine 2,3-dioxygenase-expressing leukemic dendritic cells impair a leukemia-specific immune response by inducing potent T regulatory cells

(2010) A. Curti et al.   HAEMATOLOGICA

Elevated frequencies of CD4+CD25+CD127lo regulatory T cells is associated to poor prognosis in patients with acute myeloid leukemia

(2010) Zhang Shenghui et al.   INTERNATIONAL JOURNAL OF CANCER

Depletion of endogenous tumor-associated regulatory T cells improves the efficacy of adoptive cytotoxic T-cell immunotherapy in murine acute myeloid leukemia

(2009) Q. Zhou et al.   BLOOD

Increased Frequency and Suppression by Regulatory T Cells in Patients with Acute Myelogenous Leukemia

(2009) M. J. Szczepanski et al.   CLINICAL CANCER RESEARCH

In vivodepletion of CD4+FOXP3+Treg cells by the PC61 anti-CD25 monoclonal antibody is mediated by FcγRIII+phagocytes

(2009) Yulius Y. Setiady et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

B7-H1 up-regulation on dendritic-like leukemia cells suppresses T cell immune function through modulation of IL-10/IL-12 production and generation of Treg cells

(2009) Wei Ge et al.   LEUKEMIA RESEARCH