CD82 regulates STAT5/IL-10 and supports survival of acute myelogenous leukemia cells

Kit Regulates Maintenance of Quiescent Hematopoietic Stem Cells

(2014) L. A. Thoren et al.   JOURNAL OF IMMUNOLOGY

Inhibition of p38 MAPK activity promotes ex vivo expansion of human cord blood hematopoietic stem cells

(2012) Jing Zou et al.   ANNALS OF HEMATOLOGY

CD34+/CD38−acute myelogenous leukemia cells aberrantly express CD82 which regulates adhesion and survival of leukemia stem cells

(2012) Chie Nishioka et al.   INTERNATIONAL JOURNAL OF CANCER

Inhibition of MEK/ERK signaling induces apoptosis of acute myelogenous leukemia cells via inhibition of eukaryotic initiation factor 4E-binding protein 1 and down-regulation of Mcl-1

(2010) Chie Nishioka et al.   APOPTOSIS

Human acute myelogenous leukemia stem cells are rare and heterogeneous when assayed in NOD/SCID/IL2Rγc-deficient mice

(2010) Jean-Emmanuel Sarry et al.   JOURNAL OF CLINICAL INVESTIGATION

Long-term exposure of leukemia cells to multi-targeted tyrosine kinase inhibitor induces activations of AKT, ERK and STAT5 signaling via epigenetic silencing of the PTEN gene

(2010) C Nishioka et al.   LEUKEMIA

Conditional deletion of STAT5 in adult mouse hematopoietic stem cells causes loss of quiescence and permits efficient nonablative stem cell replacement

(2009) Z. Wang et al.   BLOOD

Signal Transducer and Activator of Transcription (STAT)-5A and STAT5B Differentially Regulate Human Mammary Carcinoma Cell Behavior

(2009) Jian-Zhong Tang et al.   ENDOCRINOLOGY

Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells

(2008) D. C. Taussig et al.   BLOOD

Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100

(2008) B. Nervi et al.   BLOOD