Medial Arterial Calcification

An elevated ankle-brachial index is not a valid proxy for peripheral medial arterial calcification

(2021) Anna G. Hoek et al.   ATHEROSCLEROSIS

Decreased monocyte calcium sensing receptor expression in patients with chronic kidney disease is associated with impaired monocyte ability to reduce vascular calcification.

(2021) Thibaut Objois et al.   KIDNEY INTERNATIONAL

Contribution of Gut Microbiota-Derived Uremic Toxins to the Cardiovascular System Mineralization

(2021) Iwona Filipska et al.   Toxins

The Thermodynamics of Medial Vascular Calcification

(2021) Ángel Millán et al.   Frontiers in Cell and Developmental Biology

Regulatory RNAs in Heart Failure

(2020) Clarissa Pedrosa da Costa Gomes et al.   CIRCULATION

A Novel Treatment for Vascular Calcification in Patients With Dialysis-Dependent Chronic Kidney Disease

(2020) S. Susan Hedayati   CIRCULATION

The Epigenetic Landscape of Vascular Calcification: An Integrative Perspective

(2020) Yi-Chou Hou et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Dysregulation of FOXO1 (Forkhead Box O1 Protein) Drives Calcification in Arterial Calcification due to Deficiency of CD73 and Is Present in Peripheral Artery Disease

(2020) William J. Moorhead et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Spatially Resolved Transcriptomes—Next Generation Tools for Tissue Exploration

(2020) Michaela Asp et al.   BIOESSAYS

Single Cell RNA Sequencing in Atherosclerosis Research

(2020) Jesse W. Williams et al.   CIRCULATION RESEARCH

Research Models for Studying Vascular Calcification

(2020) Jaqueline Herrmann et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

DDR1 (Discoidin Domain Receptor-1)-RhoA (Ras Homolog Family Member A) Axis Senses Matrix Stiffness to Promote Vascular Calcification

(2020) David Ngai et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Spatial molecular profiling: platforms, applications and analysis tools

(2020) Minzhe Zhang et al.   BRIEFINGS IN BIOINFORMATICS

CT calcification patterns of peripheral arteries in patients without known peripheral arterial disease

(2020) Louise C.D. Konijn et al.   EUROPEAN JOURNAL OF RADIOLOGY

Network determinants of cardiovascular calcification and repositioned drug treatments

(2020) Jun‐Seop Song et al.   FASEB JOURNAL

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

(2020) Marie AC Depuydt et al.   CIRCULATION RESEARCH

A Novel Scoring System for Small Artery Disease and Medial Arterial Calcification Is Strongly Associated With Major Adverse Limb Events in Patients With Chronic Limb-Threatening Ischemia

(2020) Roberto Ferraresi et al.   JOURNAL OF ENDOVASCULAR THERAPY

Vascular Calcification Slows But Does Not Regress After Kidney Transplantation

(2020) Harish R. Alappan et al.   Kidney International Reports

Association of infrapopliteal medial arterial calcification with lower-limb amputations in high-risk patients: A systematic review and meta-analysis

(2020) Fabrizio Losurdo et al.   VASCULAR MEDICINE

Poly(ADP-ribose) polymerase 1 accelerates vascular calcification by upregulating Runx2

(2019) Cheng Wang et al.   Nature Communications

Efficacy and Safety of Tenapanor in Patients with Hyperphosphatemia Receiving Maintenance Hemodialysis: A Randomized Phase 3 Trial

(2019) Geoffrey A. Block et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

CD73 (Cluster of Differentiation 73) and the Differences Between Mice and Humans

(2019) Pouya Joolharzadeh et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A Randomized Trial of Magnesium Oxide and Oral Carbon Adsorbent for Coronary Artery Calcification in Predialysis CKD

(2019) Yusuke Sakaguchi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Long noncoding RNAs in vascular smooth muscle cells regulate vascular calcification

(2019) Geon Jeong et al.   Scientific Reports

Genetic Association of Finger Photoplethysmography-Derived Arterial Stiffness Index With Blood Pressure and Coronary Artery Disease

(2019) Seyedeh M. Zekavat et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Multifaceted Mechanisms of Vascular Calcification in Aging

(2019) Luciana A. Pescatore et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Smooth Muscle Cell Phenotypic Diversity

(2019) Mingjun Liu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Large-Artery Stiffness in Health and Disease

(2019) Julio A. Chirinos et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Molecular imaging of endothelial activation and mineralization in a mouse model of accelerated atherosclerosis

(2019) Guillaume Rucher et al.   EJNMMI Research

Slowing Progression of Cardiovascular Calcification with SNF472 in Patients on Hemodialysis: Results of a Randomized, Phase 2b Study

(2019) Paolo Raggi et al.   CIRCULATION

Multicenter Randomized Controlled Trial of Vitamin K Antagonist Replacement by Rivaroxaban with or without Vitamin K2 in Hemodialysis Patients with Atrial Fibrillation: the Valkyrie Study

(2019) An S. De Vriese et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype

(2019) Rajeev Malhotra et al.   NATURE GENETICS

Single-cell immune landscape of human atherosclerotic plaques

(2019) Dawn M. Fernandez et al.   NATURE MEDICINE

Intravascular lithotripsy for calcific coronary and peripheral artery stenoses

(2019) Carlotta Sorini Dini et al.   EuroIntervention

Key Aspects of Myo-Inositol Hexaphosphate (Phytate) and Pathological Calcifications

(2019) Felix Grases et al.   MOLECULES

New models to study vascular mural cell embryonic origin: implications in vascular diseases

(2018) Sanjay Sinha et al.   CARDIOVASCULAR RESEARCH

Spatiotemporal Multi-omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease

(2018) Florian Schlotter et al.   CIRCULATION

Proteomic Architecture of Human Coronary and Aortic Atherosclerosis

(2018) David M. Herrington et al.   CIRCULATION

Pulsatile arterial haemodynamics in heart failure

(2018) Thomas Weber et al.   EUROPEAN HEART JOURNAL

Malignant Mönckeberg medial calcific sclerosis

(2018) Isabella Pisani et al.   Internal and Emergency Medicine

Etidronate for Prevention of Ectopic Mineralization in Patients With Pseudoxanthoma Elasticum

(2018) Guido Kranenburg et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Coronary Calcium Score and Cardiovascular Risk

(2018) Philip Greenland et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

PiT-2, a type III sodium-dependent phosphate transporter, protects against vascular calcification in mice with chronic kidney disease fed a high-phosphate diet

(2018) Shunsuke Yamada et al.   KIDNEY INTERNATIONAL

Is Matrix Gla Protein Associated with Vascular Calcification? A Systematic Review

(2018) Hilary Barrett et al.   Nutrients

The Effect of Increasing Dialysate Magnesium on Serum Calcification Propensity in Subjects with End Stage Kidney Disease

(2018) Iain Bressendorff et al.   Clinical Journal of the American Society of Nephrology

Pathology of Peripheral Artery Disease in Critical Limb Ischemia

(2018) Navneet Narula et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Media sclerosis drives and localizes atherosclerosis in peripheral arteries

(2018) Pak-Wing Fok et al.   PLoS One

CONSTITUTIVE INTERPRETATION OF ARTERIAL STIFFNESS IN CLINICAL STUDIES - A METHODOLOGICAL REVIEW

(2018) Koen D Reesink et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Aortic stiffness, pressure and flow pulsatility, and target organ damage

(2018) Gary F. Mitchell   JOURNAL OF APPLIED PHYSIOLOGY

Long Noncoding RNAs in Atherosclerosis

(2018) Zhengyi Zhang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cardiovascular calcification: artificial intelligence and big data accelerate mechanistic discovery

(2018) Maximillian A. Rogers et al.   Nature Reviews Cardiology

Pseudoxanthoma Elasticum as a Paradigm of Heritable Ectopic Mineralization Disorders

(2018) Qiaoli Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Phosphate (Pi)-regulated heterodimerization of the high-affinity sodium-dependent Pitransporters PiT1/Slc20a1 and PiT2/Slc20a2 underlies extracellular Pisensing independently of Piuptake

(2017) Nina Bon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aortic microcalcification is associated with elastin fragmentation in Marfan syndrome

(2017) Shaynah Wanga et al.   JOURNAL OF PATHOLOGY

Identifying early pathogenic events during vascular calcification in uremic rats

(2017) Luis Hortells et al.   KIDNEY INTERNATIONAL

In Vivo Calcium Detection by Comparing Optical Coherence Tomography, Intravascular Ultrasound, and Angiography

(2017) Xiao Wang et al.   JACC-Cardiovascular Imaging

Multidisciplinary Approach to Understand Medial Arterial Calcification

(2017) Ophélie Gourgas et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Phosphate—a poison for humans?

(2016) Hirotaka Komaba et al.   KIDNEY INTERNATIONAL

Increased activity of TNAP compensates for reduced adenosine production and promotes ectopic calcification in the genetic disease ACDC

(2016) H. Jin et al.   Science Signaling

Increased activity of TNAP compensates for reduced adenosine production and promotes ectopic calcification in the genetic disease ACDC

(2016) H. Jin et al.   Science Signaling

Porcelain Aorta: A Comprehensive Review

(2015) Y. Abramowitz et al.   CIRCULATION

Phosphate uptake-independent signaling functions of the type III sodium-dependent phosphate transporter, PiT-1, in vascular smooth muscle cells

(2015) Nicholas W. Chavkin et al.   EXPERIMENTAL CELL RESEARCH

Exome and genome sequencing: a revolution for the discovery and diagnosis of monogenic disorders

(2015) H. Stranneheim et al.   JOURNAL OF INTERNAL MEDICINE

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

(2015) Jenny C Taylor et al.   NATURE GENETICS

Intravascular Imaging of Coronary Calcification and Its Clinical Implications

(2015) Gary S. Mintz   JACC-Cardiovascular Imaging

Magnesium modulates the expression levels of calcification-associated factors to inhibit calcification in a time-dependent manner

(2015) JINSHENG XU et al.   Experimental and Therapeutic Medicine

Prognostic implications of severe coronary calcification in patients undergoing coronary artery bypass surgery: An analysis of the SYNTAX Study

(2014) Christos V. Bourantas et al.   CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS

Medial vascular calcification revisited: review and perspectives

(2014) P. Lanzer et al.   EUROPEAN HEART JOURNAL

Below-Knee Arterial Calcification in Type 2 Diabetes: Association With Receptor Activator of Nuclear Factor κB Ligand, Osteoprotegerin, and Neuropathy

(2014) Olivier Bourron et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Ischemic Outcomes After Coronary Intervention of Calcified Vessels in Acute Coronary Syndromes

(2014) Philippe Généreux et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Coronary Artery Calcification

(2014) Mahesh V. Madhavan et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Gastrointestinal Inhibition of Sodium-Hydrogen Exchanger 3 Reduces Phosphorus Absorption and Protects against Vascular Calcification in CKD

(2014) E. D. Labonte et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Computed Tomography of Aortic Wall Calcifications in Aortic Dissection Patients

(2014) Pim A. de Jong et al.   PLoS One

Matrix Gla Protein Species and Risk of Cardiovascular Events in Type 2 Diabetic Patients

(2013) G. W. Dalmeijer et al.   DIABETES CARE

Angiotensin II–dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis

(2013) Elena M. Gallo et al.   JOURNAL OF CLINICAL INVESTIGATION

Effect of calcium-based versus non-calcium-based phosphate binders on mortality in patients with chronic kidney disease: an updated systematic review and meta-analysis

(2013) Sophie A Jamal et al.   LANCET

Vascular calcification--is aldosterone a culprit?

(2013) F. Lang et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Mutations in SLC20A2 link familial idiopathic basal ganglia calcification with phosphate homeostasis

(2012) Cheng Wang et al.   NATURE GENETICS

Magnesium prevents phosphate-induced calcification in human aortic vascular smooth muscle cells

(2012) L. Louvet et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

US Assessment of Medial Arterial Calcification: A Sensitive Marker of Diabetes-related Microvascular and Macrovascular Complications

(2012) Kin Hung Liu et al.   RADIOLOGY

Association Between Chromosome 9p21 Variants and the Ankle-Brachial Index Identified by a Meta-Analysis of 21 Genome-Wide Association Studies

(2011) Joanne M. Murabito et al.   Circulation-Cardiovascular Genetics

Vascular pathology of medial arterial calcifications in NT5E deficiency: Implications for the role of adenosine in pseudoxanthoma elasticum

(2011) Thomas C. Markello et al.   MOLECULAR GENETICS AND METABOLISM

NT5EMutations and Arterial Calcifications

(2011) Cynthia St. Hilaire et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of calcium-phosphate deposition in vascular smooth muscle cell calcification

(2010) Ricardo Villa-Bellosta et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Recent progress in the treatment of vascular calcification

(2010) W. Charles O'Neill et al.   KIDNEY INTERNATIONAL

Marfan syndrome. Part 1: pathophysiology and diagnosis

(2010) Victoria Cañadas et al.   Nature Reviews Cardiology

The ADVANCE study: a randomized study to evaluate the effects of cinacalcet plus low-dose vitamin D on vascular calcification in patients on hemodialysis

(2010) P. Raggi et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Aortic Calcification Is Associated With Aortic Stiffness and Isolated Systolic Hypertension in Healthy Individuals

(2009) Carmel M. McEniery et al.   HYPERTENSION

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Calcification is associated with loss of functional calcium-sensing receptor in vascular smooth muscle cells

(2008) Masih-ul Alam et al.   CARDIOVASCULAR RESEARCH

Hypophosphatemia, Hyperphosphaturia, and Bisphosphonate Treatment Are Associated With Survival Beyond Infancy in Generalized Arterial Calcification of Infancy

(2008) Frank Rutsch et al.   Circulation-Cardiovascular Genetics

Medial Artery Calcification as an Indicator of Diabetic Peripheral Vascular Disease

(2008) Christopher David Smith et al.   FOOT & ANKLE INTERNATIONAL

Mechanotransduction gone awry

(2008) Diana E. Jaalouk et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Arterial tortuosity syndrome: clinical and molecular findings in 12 newly identified families

(2007) B.L. Callewaert et al.   HUMAN MUTATION