Fusion Peptide of SARS-CoV-2 Spike Rearranges into a Wedge Inserted in Bilayered Micelles

SARS-CoV-2 Fusion Peptide has a Greater Membrane Perturbating Effect than SARS-CoV with Highly Specific Dependence on Ca2+

(2021) Alex L. Lai et al.   JOURNAL OF MOLECULAR BIOLOGY

NMR Model of the Entire Membrane-Interacting Region of the HIV-1 Fusion Protein and Its Perturbation of Membrane Morphology

(2021) Alessandro Piai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Trimeric Hydrophobic Zipper Mediates the Intramembrane Assembly of SARS-CoV-2 Spike

(2021) Qingshan Fu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2

(2020) Renhong Yan et al.   SCIENCE

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

(2020) Shuai Xia et al.   CELL RESEARCH

Cell entry mechanisms of SARS-CoV-2

(2020) Jian Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein

(2020) Alessandro Piai et al.   Nature Communications

Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV

(2020) Xiuyuan Ou et al.   Nature Communications

Coronavirus membrane fusion mechanism offers a potential target for antiviral development

(2020) Tiffany Tang et al.   ANTIVIRAL RESEARCH

Bicelles Rich in both Sphingolipids and Cholesterol and Their Use in Studies of Membrane Proteins

(2020) James M. Hutchison et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Distinct conformational states of SARS-CoV-2 spike protein

(2020) Yongfei Cai et al.   SCIENCE

Cryo-EM analysis of the post-fusion structure of the SARS-CoV spike glycoprotein

(2020) Xiaoyi Fan et al.   Nature Communications

Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains

(2020) Tongqing Zhou et al.   Cell Host & Microbe

Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM

(2020) Cong Xu et al.   Science Advances

A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike

(2019) Shuai Xia et al.   Science Advances

Low q Bicelles are Mixed Micelles

(2018) Tracy Caldwell et al.   Journal of Physical Chemistry Letters

The SARS-CoV Fusion Peptide Forms an Extended Bipartite Fusion Platform that Perturbs Membrane Order in a Calcium-Dependent Manner

(2017) Alex L. Lai et al.   JOURNAL OF MOLECULAR BIOLOGY

Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion

(2017) Alexandra C. Walls et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improvements to the APBS biomolecular solvation software suite

(2017) Elizabeth Jurrus et al.   PROTEIN SCIENCE

Optimal Bicelle Sizeqfor Solution NMR Studies of the Protein Transmembrane Partition

(2016) Alessandro Piai et al.   CHEMISTRY-A EUROPEAN JOURNAL

Closed and Semiclosed Interhelical Structures in Membrane vs Closed and Open Structures in Detergent for the Influenza Virus Hemagglutinin Fusion Peptide and Correlation of Hydrophobic Surface Area with Fusion Catalysis

(2015) Ujjayini Ghosh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Charge-Triggered Membrane Insertion of Matrix Metalloproteinase-7, Supporter of Innate Immunity and Tumors

(2015) Stephen H. Prior et al.   STRUCTURE

Viral membrane fusion

(2015) Stephen C. Harrison   VIROLOGY

Substitution at Aspartic Acid 1128 in the SARS Coronavirus Spike Glycoprotein Mediates Escape from a S2 Domain-Targeting Neutralizing Monoclonal Antibody

(2014) Oi-Wing Ng et al.   PLoS One

Ambidextrous binding of cell and membrane bilayers by soluble matrix metalloproteinase-12

(2014) Rama K. Koppisetti et al.   Nature Communications

Mechanisms of Virus Membrane Fusion Proteins

(2014) Margaret Kielian   Annual Review of Virology

Bicelles at Low Concentrations

(2012) Zhenwei Lu et al.   MOLECULAR PHARMACEUTICS

Human Monoclonal Antibodies against Highly Conserved HR1 and HR2 Domains of the SARS-CoV Spike Protein Are More Broadly Neutralizing

(2012) Hatem A. Elshabrawy et al.   PLoS One

Spin echo NMR spectra without J modulation

(2011) Juan A. Aguilar et al.   CHEMICAL COMMUNICATIONS

Antiparallel EmrE exports drugs by exchanging between asymmetric structures

(2011) Emma A. Morrison et al.   NATURE

Structure and function of the complete internal fusion loop from Ebolavirus glycoprotein 2

(2011) S. M. Gregory et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic structure of membrane-anchored Arf•GTP

(2010) Yizhou Liu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The complete influenza hemagglutinin fusion domain adopts a tight helical hairpin arrangement at the lipid:water interface

(2010) J. L. Lorieau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CHARMM-GUI Membrane Builder for Mixed Bilayers and Its Application to Yeast Membranes

(2009) Sunhwan Jo et al.   BIOPHYSICAL JOURNAL

Structures and Mechanisms of Viral Membrane Fusion Proteins: Multiple Variations on a Common Theme

(2008) Judith M. White et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Bilayer in Small Bicelles Revealed by Lipid−Protein Interactions Using NMR Spectroscopy

(2008) Donghan Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY