Structure, function, and biosynthesis of thiazole/oxazole-modified microcins

Engineering Unnatural Variants of Plantazolicin through Codon Reprogramming

(2013) Caitlin D. Deane et al.   ACS Chemical Biology

Structure of Microcin B-Like Compounds Produced by Pseudomonas syringae and Species Specificity of Their Antibacterial Action

(2013) M. Metelev et al.   JOURNAL OF BACTERIOLOGY

Insights into the Mechanism of Peptide Cyclodehydrations Achieved through the Chemoenzymatic Generation of Amide Derivatives

(2013) Kyle L. Dunbar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural and functional insight into an unexpectedly selective N-methyltransferase involved in plantazolicin biosynthesis

(2013) J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of YM-216391 Biosynthetic Gene Cluster and Improvement of the Cyclopeptide Production in a Heterologous Host

(2012) Xiao-Hong Jian et al.   ACS Chemical Biology

Three-Dimensional Solution Structure of Bottromycin A2: A Potent Antibiotic Active against Methicillin-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococci

(2012) Hiroaki Gouda et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Structures of Cyanobactin Maturation Enzymes Define a Family of Transamidating Proteases

(2012) Vinayak Agarwal et al.   CHEMISTRY & BIOLOGY

Synthetic Biotechnology to Study and Engineer Ribosomal Bottromycin Biosynthesis

(2012) Liujie Huo et al.   CHEMISTRY & BIOLOGY

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

(2012) Paul G. Arnison et al.   NATURAL PRODUCT REPORTS

YcaO domains use ATP to activate amide backbones during peptide cyclodehydrations

(2012) Kyle L Dunbar et al.   Nature Chemical Biology

Structure and Biosynthesis of the Antibiotic Bottromycin D

(2012) Yanpeng Hou et al.   ORGANIC LETTERS

Analysis of an Inactive Cyanobactin Biosynthetic Gene Cluster Leads to Discovery of New Natural Products from Strains of the Genus Microcystis

(2012) Niina Leikoski et al.   PLoS One

Metagenome Mining Reveals Polytheonamides as Posttranslationally Modified Ribosomal Peptides

(2012) M. F. Freeman et al.   SCIENCE

Posttranslational β-methylation and macrolactamidination in the biosynthesis of the bottromycin complex of ribosomal peptide antibiotics

(2012) Juan Pablo Gomez-Escribano et al.   Chemical Science

Identification and characterisation of the gene cluster for the anti-MRSA antibiotic bottromycin: expanding the biosynthetic diversity of ribosomal peptides

(2012) William J. K. Crone et al.   Chemical Science

Structure Determination and Interception of Biosynthetic Intermediates for the Plantazolicin Class of Highly Discriminating Antibiotics

(2011) Katie J. Molohon et al.   ACS Chemical Biology

Identification and Characterization of the Anti-Methicillin-Resistant Staphylococcus aureus WAP-8294A2 Biosynthetic Gene Cluster from Lysobacter enzymogenes OH11

(2011) Wei Zhang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antifungal thiopeptide cyclothiazomycin B1 exhibits growth inhibition accompanying morphological changes via binding to fungal cell wall chitin

(2011) Naoko Mizuhara et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Linking Chemistry and Genetics in the Growing Cyanobactin Natural Products Family

(2011) Mohamed S. Donia et al.   CHEMISTRY & BIOLOGY

Thiazole/oxazole-modified microcins: complex natural products from ribosomal templates

(2011) Joel O Melby et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A Major Portion of DNA Gyrase Inhibitor Microcin B17 Undergoes anN,O-Peptidyl Shift during Synthesis

(2011) Dmitry Ghilarov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enzymatic Basis of Ribosomal Peptide Prenylation in Cyanobacteria

(2011) John A. McIntosh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A mass spectrometry–guided genome mining approach for natural product peptidogenomics

(2011) Roland D Kersten et al.   Nature Chemical Biology

Streptolysin S-like virulence factors: the continuing sagA

(2011) Evelyn M. Molloy et al.   NATURE REVIEWS MICROBIOLOGY

Plantazolicin A and B: Structure Elucidation of Ribosomally Synthesized Thiazole/Oxazole Peptides fromBacillus amyloliquefaciensFZB42

(2011) Bahar Kalyon et al.   ORGANIC LETTERS

Genome Mining Demonstrates the Widespread Occurrence of Gene Clusters Encoding Bacteriocins in Cyanobacteria

(2011) Hao Wang et al.   PLoS One

Identification of the thiazolyl peptide GE37468 gene cluster fromStreptomycesATCC 55365 and heterologous expression inStreptomyces lividans

(2011) Travis S. Young et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification and Analysis of the Biosynthetic Gene Cluster Encoding the Thiopeptide Antibiotic Cyclothiazomycin in Streptomyces hygroscopicus 10-22

(2010) J. Wang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Cyanobactins—ribosomal cyclic peptides produced by cyanobacteria

(2010) Kaarina Sivonen et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Bottromycin derivatives: Efficient chemical modifications of the ester moiety and evaluation of anti-MRSA and anti-VRE activities

(2010) Yutaka Kobayashi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Expansion of ribosomally produced natural products: a nitrile hydratase- and Nif11-related precursor family

(2010) Daniel H Haft et al.   BMC BIOLOGY

Marine Molecular Machines: Heterocyclization in Cyanobactin Biosynthesis

(2010) John A. McIntosh et al.   CHEMBIOCHEM

Genome mining for ribosomally synthesized natural products

(2010) Juan E Velásquez et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Plantazolicin, a Novel Microcin B17/Streptolysin S-Like Natural Product from Bacillus amyloliquefaciens FZB42

(2010) R. Scholz et al.   JOURNAL OF BACTERIOLOGY

Clostridiolysin S, a Post-translationally Modified Biotoxin fromClostridium botulinum

(2010) David J. Gonzalez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Determinants of Microbial Resistance to Thiopeptide Antibiotics

(2010) Sascha Baumann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Insights into Heterocyclization from Two Highly Similar Enzymes

(2010) John A. McIntosh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genetic Interception and Structural Characterization of Thiopeptide Cyclization Precursors fromBacillus cereus

(2010) Albert A. Bowers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Circular Logic: Nonribosomal Peptide-like Macrocyclization with a Ribosomal Peptide Catalyst

(2010) John A. McIntosh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total synthesis of the large non-ribosomal peptide polytheonamide B

(2010) Masayuki Inoue et al.   Nature Chemistry

Conopeptide characterization and classifications: An analysis using ConoServer

(2010) Quentin Kaas et al.   TOXICON

Nosiheptide Biosynthesis Featuring a Unique Indole Side Ring Formation on the Characteristic Thiopeptide Framework

(2009) Yi Yu et al.   ACS Chemical Biology

Structure Determination and Total Synthesis of Bottromycin A2: A Potent Antibiotic against MRSA and VRE

(2009) Hiroyuki Shimamura et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Diverse Cyanobactins in Strains of the Genus Anabaena

(2009) N. Leikoski et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Biosynthesis of Indolocarbazole and Goadsporin, Two Different Heterocyclic Antibiotics Produced by Actinomycetes

(2009) Hiroyasu ONAKA   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Thiopeptide Biosynthesis Featuring Ribosomally Synthesized Precursor Peptides and Conserved Posttranslational Modifications

(2009) Rijing Liao et al.   CHEMISTRY & BIOLOGY

Thiostrepton Biosynthesis: Prototype for a New Family of Bacteriocins

(2009) Wendy L. Kelly et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ribosomally Synthesized Thiopeptide Antibiotics Targeting Elongation Factor Tu

(2009) Rowan P. Morris et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Using Marine Natural Products to Discover a Protease that Catalyzes Peptide Macrocyclization of Diverse Substrates

(2009) Jaeheon Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds

(2009) John A. McIntosh et al.   NATURAL PRODUCT REPORTS

Follow the leader: the use of leader peptides to guide natural product biosynthesis

(2009) Trent J Oman et al.   Nature Chemical Biology

Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin

(2009) Laura C. Wieland Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Translational Regulation via L11: Molecular Switches on the Ribosome Turned On and Off by Thiostrepton and Micrococcin

(2008) Joerg M. Harms et al.   MOLECULAR CELL

A global assembly line for cyanobactins

(2008) Mohamed S Donia et al.   Nature Chemical Biology

Discovery of a widely distributed toxin biosynthetic gene cluster

(2008) S. W. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA