Thermodynamic Compensation in Peptides Following Liquid–Liquid Phase Separation

The (un)structural biology of biomolecular liquid-liquid phase separation using NMR spectroscopy

(2020) Anastasia C. Murthy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Model for disordered proteins with strongly sequence-dependent liquid phase behavior

(2020) Antonia Statt et al.   JOURNAL OF CHEMICAL PHYSICS

TDP-43 α-helical structure tunes liquid–liquid phase separation and function

(2020) Alexander E. Conicella et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physical Chemistry of the Protein Backbone: Enabling the Mechanisms of Intrinsic Protein Disorder

(2020) Justin A. Drake et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Hydropathy Patterning Complements Charge Patterning to Describe Conformational Preferences of Disordered Proteins

(2020) Wenwei Zheng et al.   Journal of Physical Chemistry Letters

Liquid–liquid phase separation of type II diabetes-associated IAPP initiates hydrogelation and aggregation

(2020) Lior Pytowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Liquid–Liquid Phase Separation in the Compartmentalization of Cell Nucleus and Spatial Genome Organization

(2020) S. V. Razin et al.   BIOCHEMISTRY-MOSCOW

Liquid-Liquid Phase Separation in Neuronal Development and Synaptic Signaling

(2020) Xiandeng Wu et al.   DEVELOPMENTAL CELL

Liquid-liquid phase separation induces pathogenic tau conformations in vitro

(2020) Nicholas M. Kanaan et al.   Nature Communications

Dehydration entropy drives liquid-liquid phase separation by molecular crowding

(2020) Sohee Park et al.   Communications Chemistry

Unraveling Molecular Interactions in Liquid–Liquid Phase Separation of Disordered Proteins by Atomistic Simulations

(2020) Matteo Paloni et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Emerging Role of the Nucleolar Stress Response in Autophagy

(2019) Astrid S. Pfister   Frontiers in Cellular Neuroscience

Temperature, Hydrostatic Pressure, and Osmolyte Effects on Liquid-Liquid Phase Separation in Protein Condensates: Physical Chemistry and Biological Implications

(2019) Roland Hermann Alfons Winter et al.   CHEMISTRY-A EUROPEAN JOURNAL

Entropy and Information within Intrinsically Disordered Protein Regions

(2019) Iva Pritišanac et al.   Entropy

Molecular interactions underlying liquid−liquid phase separation of the FUS low-complexity domain

(2019) Anastasia C. Murthy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Liquid–Liquid Phase Separation in Disease

(2019) Simon Alberti et al.   Annual Review of Genetics

LASSI: A lattice model for simulating phase transitions of multivalent proteins

(2019) Jeong-Mo Choi et al.   PLoS Computational Biology

Thermodynamics of Conformational Transitions in a Disordered Protein Backbone Model

(2018) Justin A. Drake et al.   BIOPHYSICAL JOURNAL

PDB2ENTROPY and PDB2TRENT: Conformational and Translational–Rotational Entropy from Molecular Ensembles

(2018) Federico Fogolari et al.   Journal of Chemical Information and Modeling

Peptide Solubility Limits: Backbone and Side-Chain Interactions

(2018) Rahul Sarma et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Sequence determinants of protein phase behavior from a coarse-grained model

(2018) Gregory L. Dignon et al.   PLoS Computational Biology

Relation between single-molecule properties and phase behavior of intrinsically disordered proteins

(2018) Gregory L. Dignon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Controllable protein phase separation and modular recruitment to form responsive membraneless organelles

(2018) Benjamin S. Schuster et al.   Nature Communications

Physical Chemistry of Cellular Liquid Phase Separation

(2018) Emily P. Bentley et al.   CHEMISTRY-A EUROPEAN JOURNAL

Entropy in molecular recognition by proteins

(2017) José A. Caro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrinsically Disordered Proteome of Human Membrane-Less Organelles

(2017) April L. Darling et al.   PROTEOMICS

The liquid structure of elastin

(2017) Sarah Rauscher et al.   eLife

Phase Separation: Linking Cellular Compartmentalization to Disease

(2016) Adriano Aguzzi et al.   TRENDS IN CELL BIOLOGY

ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB

(2015) James A. Maier et al.   Journal of Chemical Theory and Computation

Force field-dependent solution properties of glycine oligomers

(2015) Justin A. Drake et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Tudor Staphylococcal Nuclease Links Formation of Stress Granules and Processing Bodies with mRNA Catabolism in Arabidopsis

(2015) Emilio Gutierrez-Beltran et al.   PLANT CELL

Protein collapse driven against solvation free energy without H-bonds

(2015) Deepti Karandur et al.   PROTEIN SCIENCE

Liquid-Liquid Phase Separation in Biology

(2014) Anthony A. Hyman et al.   Annual Review of Cell and Developmental Biology

Classification of Intrinsically Disordered Regions and Proteins

(2014) Robin van der Lee et al.   CHEMICAL REVIEWS

Solubility and Aggregation of Gly5 in Water

(2014) Deepti Karandur et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Altered Ribostasis: RNA-Protein Granules in Degenerative Disorders

(2013) Mani Ramaswami et al.   CELL

PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data

(2013) Daniel R. Roe et al.   Journal of Chemical Theory and Computation

Comparing distance metrics for rotation using thek-nearest neighbors algorithm for entropy estimation

(2013) David J. Huggins   JOURNAL OF COMPUTATIONAL CHEMISTRY

Revisiting the Nucleolus: From Marker to Dynamic Integrator of Cancer Signaling

(2012) D. Ruggero   Science Signaling

Backbone-Driven Collapse in Unfolded Protein Chains

(2011) Daniel P. Teufel et al.   JOURNAL OF MOLECULAR BIOLOGY

Peptide Conformational Preferences in Osmolyte Solutions: Transfer Free Energies of Decaalanine

(2011) Hironori Kokubo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydrophilic Linkers and Polar Contacts Affect Aggregation of FG Repeat Peptides

(2010) Nicole Dölker et al.   BIOPHYSICAL JOURNAL

Statistical thermodynamics of liquid-liquid phase separation in ternary systems during complex coacervation

(2010) Nisha Pawar et al.   PHYSICAL REVIEW E

Net charge per residue modulates conformational ensembles of intrinsically disordered proteins

(2010) A. H. Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Driving ribosome assembly

(2009) Dieter Kressler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

PACKMOL: A package for building initial configurations for molecular dynamics simulations

(2009) L. Martínez et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

TrimethylamineN-oxide influence on the backbone of proteins: An oligoglycine model

(2009) Char Y. Hu et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Role of Backbone−Solvent Interactions in Determining Conformational Equilibria of Intrinsically Disordered Proteins

(2008) Hoang T. Tran et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural thermodynamics of protein preferential solvation: Osmolyte solvation of proteins, aminoacids, and peptides

(2008) Matthew Auton et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS