Dencichine prevents ovariectomy-induced bone loss and inhibits osteoclastogenesis by inhibiting RANKL-associated NF-κB and MAPK signaling pathways

Dencichine ameliorates renal injury by improving oxidative stress, apoptosis and fibrosis in diabetic rats

(2020) Chao Huang et al.   LIFE SCIENCES

l -tetrahydropalmatine suppresses osteoclastogenesis in vivo and in vitro via blocking RANK-TRAF6 interactions and inhibiting NF-κB and MAPK pathways

(2019) Xin Zhi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Protein phosphatase 2A as a new target for downregulating osteoclastogenesis and alleviating titanium particle-induced bone resorption

(2018) Liangliang Wang et al.   Acta Biomaterialia

Structure-based development of an osteoprotegerin-like glycopeptide that blocks RANKL/RANK interactions and reduces ovariectomy-induced bone loss in mice

(2018) Chao Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Proteasome inhibitor bortezomib is a novel therapeutic agent for focal radiation-induced osteoporosis

(2018) Abhishek Chandra et al.   FASEB JOURNAL

Inhibitory Effect of Purpurogallin on Osteoclast Differentiation in Vitro through the Downregulation of c-Fos and NFATc1

(2018) Kiryeong Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

D-dencichine Regulates Thrombopoiesis by Promoting Megakaryocyte Adhesion, Migration and Proplatelet Formation

(2018) Shilan Ding et al.   Frontiers in Pharmacology

A Matrine Derivative M54 Suppresses Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss by Targeting Ribosomal Protein S5

(2018) Zhi Xin et al.   Frontiers in Pharmacology

18β-Glycyrrhetinic Acid Inhibits Osteoclastogenesis In Vivo and In Vitro by Blocking RANKL-Mediated RANK–TRAF6 Interactions and NF-κB and MAPK Signaling Pathways

(2018) Xiao Chen et al.   Frontiers in Pharmacology

Clinical effects and risk factors of far cortical locking system in the treatment of lower limb fractures

(2018) Renkai Wang et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Evodiamine inhibits RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss in mice

(2018) Haiming Jin et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Helvolic acid attenuates osteoclast formation and function via suppressing RANKL-induced NFATc1 activation

(2018) Kai Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Huo Xue Tong Luo capsule, a vasoactive herbal formula prevents progression of asymptomatic osteonecrosis of femoral head: A prospective study

(2018) Qiu-Shi Wei et al.   Journal of Orthopaedic Translation

The facile synthesis of copper oxide quantum dots on chitosan with assistance of phyto-angelica for enhancing the human osteoblast activity to the application of osteoporosis

(2018) Zhongqing Hu et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Dencichine ameliorates kidney injury in induced type II diabetic nephropathy via the TGF-β/Smad signalling pathway

(2017) Li Jie et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Matrine prevents bone loss in ovariectomized mice by inhibiting RANKL-induced osteoclastogenesis

(2017) Xiao Chen et al.   FASEB JOURNAL

FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging

(2017) Hanjun Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of the combined Herba Epimedii and Fructus Ligustri Lucidi on bone turnover and TGF-β1/Smads pathway in GIOP rats

(2017) Yan Yang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway

(2017) Mengrui Wu et al.   Nature Communications

Interleukin-32 Gamma Stimulates Bone Formation by Increasing miR-29a in Osteoblastic Cells and Prevents the Development of Osteoporosis

(2017) Eun-Jin Lee et al.   Scientific Reports

Dual effect of WIN-34B on osteogenesis and osteoclastogenesis in cytokine-induced mesenchymal stem cells and bone marrow cells

(2016) Byung-Kwan Seo et al.   JOURNAL OF ETHNOPHARMACOLOGY

Serotonin-reuptake inhibitors act centrally to cause bone loss in mice by counteracting a local anti-resorptive effect

(2016) María José Ortuño et al.   NATURE MEDICINE

LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption

(2016) Jian Luo et al.   NATURE MEDICINE

Dioscin reduces ovariectomy-induced bone loss by enhancing osteoblastogenesis and inhibiting osteoclastogenesis

(2016) Xufeng Tao et al.   PHARMACOLOGICAL RESEARCH

RANKL/RANK: from bone loss to the prevention of breast cancer

(2016) Verena Sigl et al.   Open Biology

Nitidine chloride prevents OVX-induced bone loss via suppressing NFATc1-mediated osteoclast differentiation

(2016) Qian Liu et al.   Scientific Reports

The Inhibitory Effect ofAngelica tenuissimaWater Extract on Receptor Activator of Nuclear Factor-Kappa-B Ligand-Induced Osteoclast Differentiation and Bone Resorbing Activity of Mature Osteoclasts

(2015) Sung-Jun Ahn et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Matrine derivative WM130 inhibits hepatocellular carcinoma by suppressing EGFR/ERK/MMP-2 and PTEN/AKT signaling pathways

(2015) Liqiang Qian et al.   CANCER LETTERS

Dedicated Perioperative Hip Fracture Comanagement Programs are Cost-effective in High-volume Centers: An Economic Analysis

(2015) Eric Swart et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Epoxyeicosanoids suppress osteoclastogenesis and prevent ovariectomy-induced bone loss

(2015) Hanfeng Guan et al.   FASEB JOURNAL

Blockade of TNF-α-induced NF-κB signaling pathway and anti-cancer therapeutic response of dihydrotanshinone I

(2015) Fei Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Urokinase Receptor Mediates Osteoclastogenesis via M-CSF Release From Osteoblasts and the c-Fms/PI3K/Akt/NF-κB Pathway in Osteoclasts

(2015) Parnian Kalbasi Anaraki et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Inhibition of Osteoclastogenesis and Bone Resorption in vitro and in vivo by a prenylflavonoid xanthohumol from hops

(2015) Jing Li et al.   Scientific Reports

The epidemiology and management of postmenopausal osteoporosis: a viewpoint from Brazil

(2015) Luiz Francisco Baccaro et al.   Clinical Interventions in Aging

Decichine enhances hemostasis of activated platelets via AMPA receptors

(2014) Ling-Fang Huang et al.   THROMBOSIS RESEARCH

Caffeic acid 3,4-dihydroxy-phenethyl ester suppresses receptor activator of NF-κB ligand-induced osteoclastogenesis and prevents ovariectomy-induced bone loss through inhibition of mitogen-activated protein kinase/activator protein 1 and Ca2+-nuclear fact

(2012) Xian Wu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Orai1-mediated calcium entry plays a critical role in osteoclast differentiation and function by regulating activation of the transcription factor NFATc1

(2011) Sung-Yong Hwang et al.   FASEB JOURNAL

Maslinic acid suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss by regulating RANKL-mediated NF-κB and MAPK signaling pathways

(2010) Chenghai Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH