Periostin deficiency reduces diethylnitrosamine ‐induced liver cancer in mice by decreasing hepatic stellate cell activation and cancer cell proliferation

Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation

(2020) Handong Ma et al.   Cell Reports

The role of molecular enrichment on future therapies in hepatocellular carcinoma

(2018) Jean-Charles Nault et al.   JOURNAL OF HEPATOLOGY

Integrating the Epigenome to Identify Novel Drivers of Hepatocellular Carcinoma

(2018) R A Hlady et al.   HEPATOLOGY

The HLF/IL-6/STAT3 feedforward circuit drives hepatic stellate cell activation to promote liver fibrosis

(2017) Dai-Min Xiang et al.   GUT

A critical role of periostin in B-cell acute lymphoblastic leukemia

(2017) Z Ma et al.   LEUKEMIA

Mechanisms of hepatic stellate cell activation

(2017) Takuma Tsuchida et al.   Nature Reviews Gastroenterology & Hepatology

Activated hepatic stellate cells secrete periostin to induce stem cell-like phenotype of residual hepatocellular carcinoma cells after heat treatment

(2017) Rui Zhang et al.   Scientific Reports

Transcriptional Induction of Periostin by a Sulfatase 2–TGFβ1–SMAD Signaling Axis Mediates Tumor Angiogenesis in Hepatocellular Carcinoma

(2016) Gang Chen et al.   CANCER RESEARCH

Hepatic stellate cells induce hepatocellular carcinoma cell resistance to sorafenib through the laminin-332/α3 integrin axis recovery of focal adhesion kinase ubiquitination

(2016) Amalia Azzariti et al.   HEPATOLOGY

Periostin promotes immunosuppressive premetastatic niche formation to facilitate breast tumour metastasis

(2016) Zhe Wang et al.   JOURNAL OF PATHOLOGY

Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis

(2016) Sebastian R. Nielsen et al.   NATURE CELL BIOLOGY

Matricellular Protein Periostin Contributes to Hepatic Inflammation and Fibrosis

(2015) Yangmei Huang et al.   AMERICAN JOURNAL OF PATHOLOGY

A hepatic stellate cell gene expression signature associated with outcomes in hepatitis C cirrhosis and hepatocellular carcinoma after curative resection

(2015) David Y Zhang et al.   GUT

Hepatic stellate cell and monocyte interaction contributes to poor prognosis in hepatocellular carcinoma

(2015) Juling Ji et al.   HEPATOLOGY

Deficiency of periostin protects mice against methionine-choline-deficient diet-induced non-alcoholic steatohepatitis

(2015) Yuan Li et al.   JOURNAL OF HEPATOLOGY

Synergistic effect of pro-inflammatory TNFα and IL-17 in periostin mediated collagen deposition: Potential role in liver fibrosis

(2015) Suneetha Amara et al.   MOLECULAR IMMUNOLOGY

High-yield and high-purity isolation of hepatic stellate cells from normal and fibrotic mouse livers

(2015) Ingmar Mederacke et al.   Nature Protocols

Periostin: A New Extracellular Regulator of Obesity-Induced Hepatosteatosis

(2014) Tiantian Wu et al.   Cell Metabolism

Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα

(2014) Yan Lu et al.   JOURNAL OF CLINICAL INVESTIGATION

Stellate cells and the development of liver cancer: Therapeutic potential of targeting the stroma

(2014) Cédric Coulouarn et al.   JOURNAL OF HEPATOLOGY

Periostin, a multifunctional matricellular protein in inflammatory and tumor microenvironments

(2014) Allan Yi Liu et al.   MATRIX BIOLOGY

The role of periostin in tissue remodeling across health and disease

(2013) Simon J. Conway et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Role of the Microenvironment in the Pathogenesis and Treatment of Hepatocellular Carcinoma

(2013) Virginia Hernandez–Gea et al.   GASTROENTEROLOGY

Hepatic stellate cells in liver development, regeneration, and cancer

(2013) Chunyue Yin et al.   JOURNAL OF CLINICAL INVESTIGATION

The perivascular niche regulates breast tumour dormancy

(2013) Cyrus M. Ghajar et al.   NATURE CELL BIOLOGY

Periostin: A Bridge between Cancer Stem Cells and Their Metastatic Niche

(2012) Zhe Wang et al.   Cell Stem Cell

Interleukin-17 Signaling in Inflammatory, Kupffer Cells, and Hepatic Stellate Cells Exacerbates Liver Fibrosis in Mice

(2012) Fanli Meng et al.   GASTROENTEROLOGY

High-level expression of periostin is closely related to metastatic potential and poor prognosis of hepatocellular carcinoma

(2012) Yang Lv et al.   MEDICAL ONCOLOGY

Interactions between cancer stem cells and their niche govern metastatic colonization

(2011) Ilaria Malanchi et al.   NATURE

Hepatocellular Carcinoma

(2011) Hashem B. El-Serag   NEW ENGLAND JOURNAL OF MEDICINE

NF-κB and STAT3 – key players in liver inflammation and cancer

(2010) Guobin He et al.   CELL RESEARCH

Hepatocellular carcinoma: a global view

(2010) Ju Dong Yang et al.   Nature Reviews Gastroenterology & Hepatology

Mitogen-activated protein kinases in hepatocellular carcinoma development

(2010) Lihua Min et al.   SEMINARS IN CANCER BIOLOGY