Integrated Bioinformatics Analysis to Identify Alternative Therapeutic Targets for Alzheimer’s Disease: Insights from a Synaptic Machinery Perspective
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Title
Integrated Bioinformatics Analysis to Identify Alternative Therapeutic Targets for Alzheimer’s Disease: Insights from a Synaptic Machinery Perspective
Authors
Keywords
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Journal
JOURNAL OF MOLECULAR NEUROSCIENCE
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-08-20
DOI
10.1007/s12031-021-01893-9
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Note: Only part of the references are listed.- Identification of hub genes associated with obesity-induced hepatocellular carcinoma risk based on integrated bioinformatics analysis
- (2021) Hamid Ceylan MEDICAL ONCOLOGY
- Liposomal Form of L-Dopa and SH-Sy5y Cell-Derived Exosomes Modulate the Tyrosine Hydroxylase/Dopamine Receptor D2 Signaling Pathway in Parkinson's Rat Models
- (2021) Parastoo Zarrin et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- A bioinformatics approach for identifying potential molecular mechanisms and key genes involved in COVID-19 associated cardiac remodeling
- (2021) Hamid Ceylan Gene Reports
- MicroRNAs, DNA damage response and ageing
- (2020) Maryam Majidinia et al. BIOGERONTOLOGY
- Sulfonamides incorporating ketene N,S -acetal bioisosteres as potent carbonic anhydrase and acetylcholinesterase inhibitors
- (2020) Qëndresa Istrefi et al. ARCHIV DER PHARMAZIE
- SCN2A channelopathies in the autism spectrum of neuropsychiatric disorders: a role for pluripotent stem cells?
- (2020) Karina A. Kruth et al. Molecular Autism
- Disorders of synaptic vesicle fusion machinery
- (2020) Holly Melland et al. JOURNAL OF NEUROCHEMISTRY
- Genome-wide profiling and predicted significance of post-mortem brain microRNA in Alzheimer’s disease
- (2020) Adriane D. Henriques et al. MECHANISMS OF AGEING AND DEVELOPMENT
- The Role of NMDA Receptors in Alzheimer’s Disease
- (2019) Jinping Liu et al. Frontiers in Neuroscience
- Impaired Cognitive Function and Altered Hippocampal Synaptic Plasticity in Mice Lacking Dermatan Sulfotransferase Chst14/D4st1
- (2019) Qifa Li et al. Frontiers in Molecular Neuroscience
- Emerging Role of microRNAs in Dementia
- (2019) Sarayu Ramakrishna et al. JOURNAL OF MOLECULAR BIOLOGY
- Effect of a Prolonged Dietary Iron Intake on the Gene Expression and Activity of the Testicular Antioxidant Defense System in Rats
- (2019) Enver Fehim Kocpinar et al. BIOLOGICAL TRACE ELEMENT RESEARCH
- The Autism-Associated Gene Scn2a Contributes to Dendritic Excitability and Synaptic Function in the Prefrontal Cortex
- (2019) Perry W.E. Spratt et al. NEURON
- SNAP-25 isoforms differentially regulate synaptic transmission and long-term synaptic plasticity at central synapses
- (2019) Muhammad Irfan et al. Scientific Reports
- Synthesis, biological evaluation and in silico studies of novel N-substituted phthalazine sulfonamide compounds as potent carbonic anhydrase and acetylcholinesterase inhibitors
- (2019) Cüneyt Türkeş et al. BIOORGANIC CHEMISTRY
- Targeting the Synapse in Alzheimer’s Disease
- (2019) Johanna Jackson et al. Frontiers in Neuroscience
- Targeting miRNAs by polyphenols: Novel therapeutic strategy for aging
- (2019) Maryam Majidinia et al. BIOCHEMICAL PHARMACOLOGY
- A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation
- (2019) Alexandra Grubman et al. NATURE NEUROSCIENCE
- Examining the link between dose-dependent dietary iron intake and Alzheimer’s disease through oxidative stress in the rat cortex
- (2019) Hamid Ceylan et al. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
- New Isoindole‐1,3‐dione Substituted Sulfonamides as Potent Inhibitors of Carbonic Anhydrase and Acetylcholinesterase: Design, Synthesis, and Biological Evaluation
- (2019) Saliha Gündoğdu et al. ChemistrySelect
- DYSREGULATION OF INTRACELLULAR CALCIUM SIGNALING IN ALZHEIMER’S DISEASE
- (2018) Elena Popugaeva et al. ANTIOXIDANTS & REDOX SIGNALING
- Emerging role of MicroRNAs in peripheral nerve system
- (2018) Jiayi Zhang et al. LIFE SCIENCES
- Analysis of microRNA and Gene Expression Profiles in Alzheimer’s Disease: A Meta-Analysis Approach
- (2018) Shirin Moradifard et al. Scientific Reports
- In vitro and in vivo effects of iron on the expression and activity of glucose 6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, and glutathione reductase in rat spleen
- (2018) Nurdan Gonul Baltaci et al. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
- Synaptic dysfunction in Alzheimer's disease: Mechanisms and therapeutic strategies
- (2018) Yu Chen et al. PHARMACOLOGY & THERAPEUTICS
- PSD-93 Attenuates Amyloid-β-Mediated Cognitive Dysfunction by Promoting the Catabolism of Amyloid-β
- (2017) Linjie Yu et al. JOURNAL OF ALZHEIMERS DISEASE
- Role of Glutamate and NMDA Receptors in Alzheimer’s Disease
- (2017) Rui Wang et al. JOURNAL OF ALZHEIMERS DISEASE
- The Plasma Membrane Calcium ATPases and Their Role as Major New Players in Human Disease
- (2017) Nicholas Stafford et al. PHYSIOLOGICAL REVIEWS
- Cloning, expression, and characterization of human brain acetylcholinesterase in Escherichia coli using a SUMO fusion tag
- (2017) Hamid CEYLAN et al. TURKISH JOURNAL OF BIOLOGY
- MicroRNA in cardiovascular biology and disease
- (2017) Anna Wojciechowska et al. Advances in Clinical and Experimental Medicine
- Sex biology contributions to vulnerability to Alzheimer's disease: A think tank convened by the Women's Alzheimer's Research Initiative
- (2016) Heather M. Snyder et al. Alzheimers & Dementia
- MicroRNA in innate immunity and autophagy during mycobacterial infection
- (2016) Jin Kyung Kim et al. CELLULAR MICROBIOLOGY
- A review of the role of synaptosomal-associated protein 25 (SNAP-25) in neurological disorders
- (2016) Aneeqa Noor et al. INTERNATIONAL JOURNAL OF NEUROSCIENCE
- The Functional and Molecular Properties, Physiological Functions, and Pathophysiological Roles of GluN2A in the Central Nervous System
- (2016) Yongjun Sun et al. MOLECULAR NEUROBIOLOGY
- NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation
- (2016) René A. W. Frank et al. Nature Communications
- Aberrant expression of microRNAs as biomarker for schizophrenia: from acute state to partial remission and from peripheral blood to cortical tissue
- (2016) C-Y Lai et al. Translational Psychiatry
- Identification of Biomarkers Associated With Alzheimer’s Disease by Bioinformatics Analysis
- (2015) Yanxin Zhao et al. American Journal of Alzheimers Disease and Other Dementias
- Voltage-Gated Sodium Channels: Structure, Function, Pharmacology, and Clinical Indications
- (2015) Manuel de Lera Ruiz et al. JOURNAL OF MEDICINAL CHEMISTRY
- Human Argonaute 2 Has Diverse Reaction Pathways on Target RNAs
- (2015) Myung Hyun Jo et al. MOLECULAR CELL
- General hallmarks of microRNAs in brain evolution and development
- (2015) Wei Chen et al. RNA Biology
- Regulation of density of functional presynaptic terminals by local energy supply
- (2015) Hang Zhou et al. Molecular Brain
- The Construction of Common and Specific Significance Subnetworks of Alzheimer’s Disease from Multiple Brain Regions
- (2015) Wei Kong et al. Biomed Research International
- Predicting effective microRNA target sites in mammalian mRNAs
- (2015) Vikram Agarwal et al. eLife
- The emerging role of microRNAs in Alzheimer's disease
- (2015) Grazia D. Femminella et al. Frontiers in Physiology
- Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body disease
- (2014) Cassia R. Overk et al. BIOCHEMICAL PHARMACOLOGY
- Aberrant Regulation and Function of MicroRNAs in Cancer
- (2014) Brian D. Adams et al. CURRENT BIOLOGY
- Synaptic abnormalities in a Drosophila model of Alzheimer's disease
- (2014) S. D. Mhatre et al. Disease Models & Mechanisms
- Brain microRNAs and insights into biological functions and therapeutic potential of brain enriched miRNA-128
- (2014) Yogita K Adlakha et al. Molecular Cancer
- Neurotransmitter-mediated control of neurogenesis in the adult vertebrate brain
- (2013) D. A. Berg et al. DEVELOPMENT
- Downregulation of PMCA2 increases the vulnerability of midbrain neurons to mitochondrial complex I inhibition
- (2013) Alexander Brendel et al. NEUROTOXICOLOGY
- Neurotransmitter signaling in the pathophysiology of microglia
- (2013) María Domercq et al. Frontiers in Cellular Neuroscience
- Cholinergic-associated loss of hnRNP-A/B in Alzheimer's disease impairs cortical splicing and cognitive function in mice
- (2012) Amit Berson et al. EMBO Molecular Medicine
- Analysis of SNAP25 mRNA expression and promoter DNA methylation in brain areas of Alzheimer’s Disease patients
- (2012) T.K. Furuya et al. NEUROSCIENCE
- NCBI GEO: archive for functional genomics data sets—update
- (2012) Tanya Barrett et al. NUCLEIC ACIDS RESEARCH
- Integrating the Alzheimer's Disease Proteome and Transcriptome: A Comprehensive Network Model of a Complex Disease
- (2012) Peter Hallock et al. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
- The Expression of microRNA and microRNA Clusters in the Aging Heart
- (2012) Xiaomin Zhang et al. PLoS One
- Blockade of NMDA receptors 2A subunit in the dorsal striatum impairs the learning of a complex motor skill.
- (2011) Julie Lemay-Clermont et al. BEHAVIORAL NEUROSCIENCE
- Regulated intramembrane proteolysis - lessons from amyloid precursor protein processing
- (2011) Stefan F. Lichtenthaler et al. JOURNAL OF NEUROCHEMISTRY
- Factors responsible for neurofibrillary tangles and neuronal cell losses in tauopathy
- (2011) Yasuhito Wakasaya et al. JOURNAL OF NEUROSCIENCE RESEARCH
- MicroRNAs in inflammation and immune responses
- (2011) J Contreras et al. LEUKEMIA
- microRNA and aging: A novel modulator in regulating the aging network
- (2010) Li-Hsin Chen et al. AGEING RESEARCH REVIEWS
- MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain
- (2010) M. Somel et al. GENOME RESEARCH
- Small RNAs - secrets and surprises of the genome
- (2010) Xuemei Chen PLANT JOURNAL
- The biosynthetic pathways and biological scopes of plant small RNAs
- (2010) Franck Vazquez et al. TRENDS IN PLANT SCIENCE
- Association between NMDA receptor subunit 2b gene polymorphism and Alzheimer’s disease in Chinese Han population in Shanghai
- (2010) Chao Chen et al. Neuroscience Bulletin
- SNAP-25 in Neuropsychiatric Disorders
- (2009) Irene Corradini et al. Annals of the New York Academy of Sciences
- Differential role of sodium channelsSCN1AandSCN2Agene polymorphisms with epilepsy and multiple drug resistance in the north Indian population
- (2009) Ram Lakhan et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- MicroRNA group disorganization in aging
- (2009) Joel Lanceta et al. EXPERIMENTAL GERONTOLOGY
- Intracellular calcium signalling in Alzheimer’s disease
- (2009) Marina Hermes et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
- (2009) Da Wei Huang et al. Nature Protocols
- ToppGene Suite for gene list enrichment analysis and candidate gene prioritization
- (2009) J. Chen et al. NUCLEIC ACIDS RESEARCH
- GluN2B subunit-containing NMDA receptor antagonists prevent A -mediated synaptic plasticity disruption in vivo
- (2009) N.-W. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- STRING 8--a global view on proteins and their functional interactions in 630 organisms
- (2008) L. J. Jensen et al. NUCLEIC ACIDS RESEARCH
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