Development of [18F]AldoView as the First Highly Selective Aldosterone Synthase PET Tracer for Imaging of Primary Hyperaldosteronism

Primary Aldosteronism: Where Are We Now? Where to from Here?

(2020) John Watson Funder   HORMONE AND METABOLIC RESEARCH

Functional imaging with 11C-metomidate PET for subtype diagnosis in primary aldosteronism

(2020) Minna Soinio et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Clinical Outcomes After Unilateral Adrenalectomy for Primary Aldosteronism

(2019) Wessel M. C. M. Vorselaars et al.   JAMA Surgery

11 C‐Metomidate PET/CT is a useful adjunct for lateralization of primary aldosteronism in routine clinical practice

(2019) Paula M. O’Shea et al.   CLINICAL ENDOCRINOLOGY

Development of Highly Selective Pyrimidine-Based Aldosterone Synthase (CYP11B2) Inhibitors

(2019) Steven M. Sparks et al.   ACS Medicinal Chemistry Letters

Cellular and Genetic Causes of Idiopathic Hyperaldosteronism

(2018) Kei Omata et al.   HYPERTENSION

Ring-Closing Synthesis of Dibenzothiophene Sulfonium Salts and Their Use as Leaving Groups for Aromatic 18F-Fluorination

(2018) Thibault Gendron et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of [18F]FAMTO: A novel fluorine-18 labelled positron emission tomography (PET) radiotracer for imaging CYP11B1 and CYP11B2 enzymes in adrenal glands

(2018) Salvatore Bongarzone et al.   NUCLEAR MEDICINE AND BIOLOGY

Disordered CYP11B2 Expression in Primary Aldosteronism

(2017) Celso Gomez-Sanchez et al.   HORMONE AND METABOLIC RESEARCH

The SPARTACUS Trial: Controversies and Unresolved Issues

(2017) Felix Beuschlein et al.   HORMONE AND METABOLIC RESEARCH

Targeting CXCR4 (CXC Chemokine Receptor Type 4) for Molecular Imaging of Aldosterone-Producing AdenomaNovelty and Significance

(2017) Britta Heinze et al.   HYPERTENSION

Prevalence and Clinical Manifestations of Primary Aldosteronism Encountered in Primary Care Practice

(2017) Silvia Monticone et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Immunohistochemistry of aldosterone synthase leads the way to the pathogenesis of primary aldosteronism

(2017) Koshiro Nishimoto et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

A Novel CYP11B2-Specific Imaging Agent for Detection of Unilateral Subtypes of Primary Aldosteronism

(2016) Tsutomu Abe et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Primary Aldosteronism: Changing Definitions and New Concepts of Physiology and Pathophysiology Both Inside and Outside the Kidney

(2016) Michael Stowasser et al.   PHYSIOLOGICAL REVIEWS

Discovery of N-[5-(6-Chloro-3-cyano-1-methyl-1H-indol-2-yl)-pyridin-3-ylmethyl]-ethanesulfonamide, a Cortisol-Sparing CYP11B2 Inhibitor that Lowers Aldosterone in Human Subjects

(2015) Julien P. N. Papillon et al.   JOURNAL OF MEDICINAL CHEMISTRY

Aldosterone-stimulating somatic gene mutations are common in normal adrenal glands

(2015) Koshiro Nishimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of Benzimidazole CYP11B2 Inhibitors with in Vivo Activity in Rhesus Monkeys

(2015) Scott B. Hoyt et al.   ACS Medicinal Chemistry Letters

Sulfonium Salts as Leaving Groups for Aromatic Labelling of Drug-like Small Molecules with Fluorine-18

(2015) Kerstin Sander et al.   Scientific Reports

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Evaluation of the Sensitivity and Specificity of11C-Metomidate Positron Emission Tomography (PET)-CT for Lateralizing Aldosterone Secretion by Conn's Adenomas

(2011) Timothy J. Burton et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM