Article
Pharmacology & Pharmacy
Kohei Kawabata, Miya Kohashi, Shiori Akimoto, Hiroyuki Nishi
Summary: In this study, the photostability of felodipine (FL) medicine and its altered forms was evaluated. The residual amounts of FL after 24 h of UV irradiation were measured and two photoproducts were identified. The chemical structures of the photoproducts were determined using mass spectrometry analysis. The generation rates of the photoproducts were found to be dependent on the presence of aqueous media.
Article
Food Science & Technology
Jing Wan, Peng He, Yuanshan Chen, Qiujin Zhu
Summary: A practical, efficient, and rapid method for quantifying 19 pyrethroids in tea and orange samples was developed. Out of 262 tea samples, 11 pyrethroids were detected positive with concentrations below maximum residue limits. No pyrethroid was found in 209 peeled orange samples.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Chemistry, Medicinal
Muqeet Wahid, Fatima Saqib, Hanadi Talal Ahmedah, Claudia Mihaela Gavris, Vincenzo De Feo, Mircea Hogea, Marius Moga, Radu Chicea
Summary: Cucumis sativus seeds extract contains bioactive compounds that can regulate calcium-mediated signaling pathways by interfering with asthma and diarrhea-related target genes, exhibiting spasmolytic, anti-diarrheal, and antisecretory activities, with therapeutic effects.
Article
Biochemistry & Molecular Biology
Yili Hong, Zening Wang, Colin J. Barrow, Frank R. Dunshea, Hafiz A. R. Suleria
Summary: Stone fruits waste, including peach, nectarine, plum, and apricot, contain high phenolic content which contribute to their antioxidant potential and associated health benefits. Plum waste has higher phenolic content, apricot waste has higher tannin content and DPPH activity, nectarine waste has higher antioxidant capacity in FRAP and TAC assays, and peach waste shows higher antioxidant capacity in ABTS assay. Analysis shows that stone fruit waste contains various phenolic compounds and have potential applications in other industries.
Article
Microbiology
Jay Hind Nishad, Arti Singh, Rajnish Bharti, Priyanka Prajapati, Vijay Kumar Sharma, Vijai Kumar Gupta, Ravindra Nath Kharwar
Summary: The study demonstrated that the extract of D. longicolla treated with BRD4770 showed increased antioxidant activity and inhibition zone against S. aureus and MRSA. Analysis revealed induced antibacterial and antioxidant-like compounds in the BRD4770-treated extract, supported by mass spectrometry and high-performance liquid chromatography.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Yasir Iqbal, Eric N. Ponnampalam, Hafiz A. R. Suleria, Jeremy J. Cottrell, Frank R. Dunshea
Summary: The study qualitatively and quantitatively analyzed polyphenols in chicory and lucerne, finding that they possess high antioxidant potential mainly due to polyphenolic compounds. Both chicory and lucerne are rich in polyphenolic compounds, making them suitable natural antioxidants for use in animal feeds, human foods, and pharmaceutical formulations.
Article
Engineering, Chemical
Simiao Fan, Yunyang Qi, Linghong Shi, Marcella Giovani, Nur Afifah Ahmad Zaki, Siwei Guo, Hafiz Ansar Rasul Suleria
Summary: Avocados are an important fruit in our diet, but many avocados become defective during transportation and are rejected by consumers. However, rejected avocado pulp still contains high phenolic content that can be utilized in the food and pharmaceutical industries.
Article
Food Science & Technology
Gia Toan Vo, Ziyao Liu, Osbert Chou, Biming Zhong, Colin J. Barrow, Frank R. Dunshea, Hafiz A. R. Suleria
Summary: The study reveals the qualitative and quantitative analysis of phenolic composition and antioxidant capacity in five varieties of Australian grapes. Golden Globe grapes exhibit the highest levels of phenolic content and antioxidant capacity, while Thompson Seedless grapes excel in certain aspects.
Article
Food Science & Technology
Zihong Yang, Linghong Shi, Yunyang Qi, Cundong Xie, Wanrong Zhao, Colin J. Barrow, Frank R. Dunshea, Hafiz A. R. Suleria
Summary: This study investigated the changes in polyphenol content during pumpkin processing and comprehensively characterized and quantified the phenolic compounds using LC-ESI-QTOF-MS/MS and HPLC-PDA. The results showed that pumpkin seeds and skins had the highest total phenolic content and total antioxidant capacity, while separated pumpkin puree had a higher total condensed tannins content. Epicatechin and catechin were found to be the most abundant phenolic compounds in pumpkin seeds and skins. This study highlights the potential of pumpkins as a source of antioxidant polyphenols.
Article
Chemistry, Analytical
Kohei Kawabata, Haruka Muraoka, Masatsugu Miyara, Yaichiro Kotake, Hiroyuki Nishi
Summary: The photodegradation behavior of Nitrendipine (NTR) was studied, and two photoproducts were identified. The photodegradation pathway of NTR was speculated, and the effect of dosage form on the photostability of NTR tablets was evaluated. These findings are important for understanding the impact of NTR photodegradation on its biological activities.
ANALYTICAL SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Zhicong Chen, Biming Zhong, Colin J. Barrow, Frank R. Dunshea, Hafiz A. R. Suleria
Summary: The study aimed to extract, identify, and quantify phenolics from dragon fruits grown in Australia. The results showed that dragon fruit pulp had higher total phenolic content and stronger antioxidant capacity, while the peel had higher content of flavonoids and tannins.
ARABIAN JOURNAL OF CHEMISTRY
(2021)
Article
Environmental Sciences
Nikita Bakanov, Carolina Honert, Lisa Eichler, Gerlind U. C. Lehmann, Ralf Schulz, Carsten A. Bruehl
Summary: A simple acetonitrile-based extraction method using HPLC-ESI-MS/MS was developed for the determination of 98 current-use pesticides in soil and herbaceous vegetation. The method exhibited good accuracy and precision, with percentage recoveries ranging from 71-125% (soil) and 70-117% (vegetation), and relative standard deviations of 1-14% (soil) and 1-13% (vegetation). Matrix-matched calibration curves showed excellent linearity (R-2 > 0.99). The method was successfully applied to agricultural sites in Germany, where 44 of the 98 pesticides were detected, indicating a high qualitative load compared to EU arable soils.
Article
Chemistry, Applied
Christof B. Steingass, Jonas Burkhardt, Vicky Baeumer, Keshav Kumar, Heiko Mibus-Schoppe, Jana Zinkernagel, Patricia Esquivel, Victor M. Jimenez, Ralf Schweiggert
Summary: Anthocyanins were characterized in red cabbage, sweet potato, and Tradescantia pallida leaves. Various non-, mono-, and diacylated cyanidins were identified in red cabbage. Sweet potato leaves contained mono- and diacylated cyanidin- and peonidin glycosides, while T. pallida leaves mainly contained tetra-acylated anthocyanin tradescantin. The thermal stability of red cabbage and purple sweet potato extracts surpassed that of a commercial food dye, but still fell short compared to the stability of Tradescantia extract.
Article
Biochemical Research Methods
William Craig Byrdwell, Hari K. Kotapati, Robert Goldschmidt, Pavel Jakubec, Lucie Novakova
Summary: The study demonstrates the use of split-flow two-dimensional liquid chromatography (SF-2D-LC) and quadruple parallel mass spectrometry (LC3MS4) for analyzing NIST SRM 1849a adult/infant formula, achieving successful three-dimensional chromatographic separation with optimized separation space and mass spectrometry methods.
JOURNAL OF CHROMATOGRAPHY A
(2022)
Article
Chemistry, Analytical
Kohei Kawabata, Misaki Masumoto, Masanori Inagaki, Hiroyuki Nishi
Summary: This study investigated the photochemical behavior of triprolidine (TRP) in an aqueous media. The degradation of TRP induced by ultraviolet light (UV) irradiation was monitored using high-performance liquid chromatography (HPLC), and the structure of the photoproduct TRP-P was determined by mass spectrometry and nuclear magnetic resonance. The mechanism of TRP photodegradation was proposed based on the identified photoproduct.
ANALYTICAL SCIENCES
(2023)
Article
Biochemical Research Methods
Sunyoung Kim, Sanghee Lee, Dongbin Shin, Miyoung Yoo
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
(2015)
Article
Chemistry, Applied
Sunyoung Kim, So-Lim Park, Sanghee Lee, So-Young Lee, Sungho Ko, Miyoung Yoo
Article
Chemistry, Applied
Sunyoung Kim, Dan-Bi Kim, Sanghee Lee, Jisu Park, Dongbin Shin, Miyoung Yoo
NATURAL PRODUCT RESEARCH
(2016)
Article
Biotechnology & Applied Microbiology
Sunyoung Kim, Sanghee Lee, Tae-Gyu Nam, Dongwon Seo, Miyoung Yoo
JOURNAL OF FOOD PROTECTION
(2017)
Article
Chemistry, Applied
Sunyoung Kim, Dan-Bi Kim, Wenjie Jin, Junghyuck Park, Wonjin Yoon, Yunyeol Lee, Soyoung Kim, Sanghee Lee, Sungsoo Kim, Ok-Hwan Lee, Dongbin Shin, Miyoung Yoo
NATURAL PRODUCT RESEARCH
(2018)
Article
Biochemical Research Methods
Miyoung Yoo, Sunyoung Kim, Sanghee Lee, Dongbin Shin
JOURNAL OF CHROMATOGRAPHIC SCIENCE
(2014)
