Inflammatory Bowel Disease-Associated Colorectal Cancer: Translational Risks from Mechanisms to Medicines
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Title
Inflammatory Bowel Disease-Associated Colorectal Cancer: Translational Risks from Mechanisms to Medicines
Authors
Keywords
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Journal
Journal of Crohns & Colitis
Volume -, Issue -, Pages -
Publisher
Oxford University Press (OUP)
Online
2021-06-09
DOI
10.1093/ecco-jcc/jjab102
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Note: Only part of the references are listed.- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Colorectal cancer statistics, 2020
- (2020) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Colorectal cancer in ulcerative colitis: a Scandinavian population-based cohort study
- (2020) Ola Olén et al. LANCET
- Colorectal cancer in Crohn's disease: a Scandinavian population-based cohort study
- (2020) Ola Olén et al. Lancet Gastroenterology & Hepatology
- Tofacitinib, an Oral Janus Kinase Inhibitor: Analysis of Malignancy (Excluding Nonmelanoma Skin Cancer) Events Across the Ulcerative Colitis Clinical Program
- (2020) Gary R Lichtenstein et al. INFLAMMATORY BOWEL DISEASES
- Vedolizumab or TNF-antagonist use and risk of new or recurrent cancer in patients with inflammatory bowel disease with prior malignancy: A retrospective cohort study
- (2020) Amar Vedamurthy et al. Clinical Gastroenterology and Hepatology
- Intestinal non-canonical NFκB signaling shapes the local and systemic immune response
- (2019) Sadeesh K. Ramakrishnan et al. Nature Communications
- Cancer-induced inflammation and inflammation-induced cancer in colon: a role for S1P lyase
- (2019) Anja Schwiebs et al. ONCOGENE
- Rational and clinical development of the anti-MAdCAM monoclonal antibody for the treatment of IBD
- (2019) Marjolijn Duijvestein et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Meta‐analysis of 16 studies of the association of alcohol with colorectal cancer
- (2019) Sarah McNabb et al. INTERNATIONAL JOURNAL OF CANCER
- Vedolizumab Therapy is Ineffective for Primary Sclerosing Cholangitis in Patients With Inflammatory Bowel Disease: A GETAID Multicentre Cohort Study
- (2019) Benedicte Caron et al. Journal of Crohns & Colitis
- IL-21 Enhances the Development of Colitis-Associated Colon Cancer: Possible Involvement of Activation-Induced Cytidine Deaminase Expression
- (2019) Akemi Araki et al. JOURNAL OF IMMUNOLOGY
- FAM64A positively regulates STAT3 activity to promote Th17 differentiation and colitis-associated carcinogenesis
- (2019) Zhi-Sheng Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IBD prevalence in Lothian, Scotland, derived by capture–recapture methodology
- (2019) Gareth-Rhys Jones et al. GUT
- Inflammation and Inflammatory Cytokine Contribute to the Initiation and Development of Ulcerative Colitis and Its Associated Cancer
- (2019) Dianbo Yao et al. INFLAMMATORY BOWEL DISEASES
- Macrophage Migration Inhibitory Factor Promotes the Interaction between the Tumor, Macrophages, and T Cells to Regulate the Progression of Chemically Induced Colitis-Associated Colorectal Cancer
- (2019) Thalia Pacheco-Fernández et al. MEDIATORS OF INFLAMMATION
- Immunoprofiling of Colitis-associated and Sporadic Colorectal Cancer and its Clinical Significance
- (2019) Jae Seung Soh et al. Scientific Reports
- Prospective cohort study of appendicectomy for treatment of therapy‐refractory ulcerative colitis
- (2019) M. E. Stellingwerf et al. BRITISH JOURNAL OF SURGERY
- IBD-Associated Dysplastic Lesions Show More Chromosomal Instability Than Sporadic Adenomas
- (2019) Linda K Wanders et al. INFLAMMATORY BOWEL DISEASES
- Ustekinumab as Induction and Maintenance Therapy for Ulcerative Colitis
- (2019) Bruce E. Sands et al. NEW ENGLAND JOURNAL OF MEDICINE
- Helicobacter pylori and colorectal cancer—A bacterium going abroad?
- (2019) Julia Butt et al. PLoS Pathogens
- Inflammation-Associated Microsatellite Alterations Caused by MSH3 Dysfunction Are Prevalent in Ulcerative Colitis and Increase With Neoplastic Advancement
- (2019) Koji Munakata et al. Clinical and Translational Gastroenterology
- The Role of Adaptor Protein CARD9 in Colitis-Associated Cancer
- (2019) Xiaoming Zhong et al. Molecular Therapy-Oncolytics
- Mutational analysis identifies therapeutic biomarkers in inflammatory bowel disease-associated colorectal cancers
- (2018) Shahida Din et al. CLINICAL CANCER RESEARCH
- Circulating integrin alpha4/beta7+ lymphocytes targeted by vedolizumab have a pro-inflammatory phenotype
- (2018) James D. Lord et al. CLINICAL IMMUNOLOGY
- Evolutionary history of human colitis-associated colorectal cancer
- (2018) Ann-Marie Baker et al. GUT
- Malignancy and Mortality in Pediatric-onset Inflammatory Bowel Disease: A Systematic Review
- (2018) Martine A Aardoom et al. INFLAMMATORY BOWEL DISEASES
- The Antimicrobial Peptide CRAMP Is Essential for Colon Homeostasis by Maintaining Microbiota Balance
- (2018) Teizo Yoshimura et al. JOURNAL OF IMMUNOLOGY
- Upregulation of phosphorylated sphingosine kinase 1 expression in colitis-associated cancer
- (2018) Kizuki Yuza et al. JOURNAL OF SURGICAL RESEARCH
- RORγt-Expressing Tregs Drive the Growth of Colitis-Associated Colorectal Cancer by Controlling IL6 in Dendritic Cells
- (2018) Angelamaria Rizzo et al. Cancer Immunology Research
- Control of Intestinal Inflammation, Colitis-Associated Tumorigenesis, and Macrophage Polarization by Fibrinogen-Like Protein 2
- (2018) Ying Zhu et al. Frontiers in Immunology
- Early detection of ulcerative colitis-associated colorectal cancer
- (2018) Yu Zhen et al. Gastroenterology Report
- Retrospective Analysis of Safety of Vedolizumab in Patients With Inflammatory Bowel Diseases
- (2018) Joseph Meserve et al. Clinical Gastroenterology and Hepatology
- Streptococcus gallolyticus conspires myeloid cells to promote tumorigenesis of inflammatory bowel disease
- (2018) Yucheng Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Safety of Tofacitinib for Treatment of Ulcerative Colitis, Based on 4.4 Years of Data From Global Clinical Trials
- (2018) William J. Sandborn et al. Clinical Gastroenterology and Hepatology
- The Risk of Colectomy and Colorectal Cancer After Appendectomy in Patients With Ulcerative Colitis: A Systematic Review and Meta-analysis
- (2018) Merel E Stellingwerf et al. Journal of Crohns & Colitis
- CLA-supplemented diet accelerates experimental colorectal cancer by inducing TGF-β-producing macrophages and T cells
- (2018) T. G. Moreira et al. Mucosal Immunology
- Non-toxigenic Bacteroides fragilis (NTBF) administration reduces bacteria-driven chronic colitis and tumor development independent of polysaccharide A
- (2018) June L. Chan et al. Mucosal Immunology
- The Protective Role of Bacteroides fragilis in a Murine Model of Colitis-Associated Colorectal Cancer
- (2018) Yun Kyung Lee et al. mSphere
- Cancer Risk in 2621 Chinese Patients with Inflammatory Bowel Disease
- (2017) Jacqueline So et al. INFLAMMATORY BOWEL DISEASES
- Thiopurines in Inflammatory Bowel Disease: New Findings and Perspectives
- (2017) Nanne K H de Boer et al. Journal of Crohns & Colitis
- Epithelial TNF Receptor Signaling Promotes Mucosal Repair in Inflammatory Bowel Disease
- (2017) Emily M. Bradford et al. JOURNAL OF IMMUNOLOGY
- Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies
- (2017) Siew C Ng et al. LANCET
- Inflammatory bowel disease with primary sclerosing cholangitis: A Danish population-based cohort study 1977-2011
- (2017) Jakob Ørskov Sørensen et al. LIVER INTERNATIONAL
- The Role of Proinflammatory Pathways in the Pathogenesis of Colitis-Associated Colorectal Cancer
- (2017) Chengxin Luo et al. MEDIATORS OF INFLAMMATION
- Interleukin-22 drives nitric oxide-dependent DNA damage and dysplasia in a murine model of colitis-associated cancer
- (2017) C Wang et al. Mucosal Immunology
- Clonal evolution of colorectal cancer in IBD
- (2017) Chang-Ho R. Choi et al. Nature Reviews Gastroenterology & Hepatology
- Defective IL-23/IL-17 Axis Protects p47phox−/− Mice from Colon Cancer
- (2017) Cornelia Richter et al. Frontiers in Immunology
- Risk of New or Recurrent Cancer in Patients With Inflammatory Bowel Disease and Previous Cancer Exposed to Immunosuppressive and Anti-Tumor Necrosis Factor Agents
- (2016) Jordan Axelrad et al. Clinical Gastroenterology and Hepatology
- Genomic Alterations Observed in Colitis-Associated Cancers Are Distinct From Those Found in Sporadic Colorectal Cancers and Vary by Type of Inflammatory Bowel Disease
- (2016) Rona Yaeger et al. GASTROENTEROLOGY
- Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease−Associated Colorectal Cancers
- (2016) Ana I. Robles et al. GASTROENTEROLOGY
- The safety of vedolizumab for ulcerative colitis and Crohn's disease
- (2016) Jean-Frédéric Colombel et al. GUT
- DNA Damage and Oxidative DNA Damage in Inflammatory Bowel Disease
- (2016) Cristiana Pereira et al. Journal of Crohns & Colitis
- Inflammatory networks underlying colorectal cancer
- (2016) Audrey Lasry et al. NATURE IMMUNOLOGY
- A pathogenic role for T cell–derived IL-22BP in inflammatory bowel disease
- (2016) Penelope Pelczar et al. SCIENCE
- Chemopreventive effects of 5-aminosalicylic acid on inflammatory bowel disease-associated colorectal cancer and dysplasia: a systematic review with meta-analysis
- (2016) Xinyun Qiu et al. Oncotarget
- Crosstalk between Wnt/β-Catenin and NF-κB Signaling Pathway during Inflammation
- (2016) Bin Ma et al. Frontiers in Immunology
- IL-21/IL-21R signaling suppresses intestinal inflammation induced by DSS through regulation of Th responses in lamina propria in mice
- (2016) Yuanyuan Wang et al. Scientific Reports
- Survival of Colorectal Cancer in Patients With or Without Inflammatory Bowel Disease: A Meta-Analysis
- (2015) Baochi Ou et al. DIGESTIVE DISEASES AND SCIENCES
- Batf-dependent Th17 cells critically regulate IL-23 driven colitis-associated colon cancer
- (2015) Elise Punkenburg et al. GUT
- Foxp3+ T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation
- (2015) B-H Yang et al. Mucosal Immunology
- The ACCURE-trial: the effect of appendectomy on the clinical course of ulcerative colitis, a randomised international multicenter trial (NTR2883) and the ACCURE-UK trial: a randomised external pilot trial (ISRCTN56523019)
- (2015) Tjibbe J Gardenbroek et al. BMC Surgery
- Elevated levels of Th17 cells and Th17-related cytokines are associated with disease activity in patients with inflammatory bowel disease
- (2014) Wenyu Jiang et al. INFLAMMATION RESEARCH
- Meta-analyses of colorectal cancer risk factors
- (2013) Constance M. Johnson et al. CANCER CAUSES & CONTROL
- Mutant p53 Prolongs NF-κB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer
- (2013) Tomer Cooks et al. CANCER CELL
- Interleukin-11 Is the Dominant IL-6 Family Cytokine during Gastrointestinal Tumorigenesis and Can Be Targeted Therapeutically
- (2013) Tracy L. Putoczki et al. CANCER CELL
- PI3K/AKT Signaling Is Essential for Communication between Tissue-Infiltrating Mast Cells, Macrophages, and Epithelial Cells in Colitis-Induced Cancer
- (2013) M. W. Khan et al. CLINICAL CANCER RESEARCH
- Population-based epidemiology, malignancy risk, and outcome of primary sclerosing cholangitis
- (2013) Kirsten Boonstra et al. HEPATOLOGY
- Increased Prevalence of Circulating Novel IL-17 Secreting Foxp3 Expressing CD4+ T Cells and Defective Suppressive Function of Circulating Foxp3+ Regulatory Cells Support Plasticity Between Th17 and Regulatory T Cells in Inflammatory Bowel Disease Patients
- (2013) Aito Ueno et al. INFLAMMATORY BOWEL DISEASES
- Colorectal cancer in inflammatory bowel disease: Results of the 3rd ECCO pathogenesis scientific workshop (I)
- (2013) Shaji Sebastian et al. Journal of Crohns & Colitis
- Clinical Outcome of IBD-Associated versus Sporadic Colorectal Cancer: A Matched-Pair Analysis
- (2013) Bernhard W. Renz et al. JOURNAL OF GASTROINTESTINAL SURGERY
- p53 Mediates TNF-Induced Epithelial Cell Apoptosis in IBD
- (2012) Tatiana Goretsky et al. AMERICAN JOURNAL OF PATHOLOGY
- Opposing Roles for IL-23 and IL-12 in Maintaining Occult Cancer in an Equilibrium State
- (2012) Michele W. L. Teng et al. CANCER RESEARCH
- Role of IL-17A in the development of colitis-associated cancer
- (2012) Y. S. Hyun et al. CARCINOGENESIS
- Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties
- (2012) Sarah Schwitalla et al. CELL
- Risk of Colorectal Cancer in Patients With Ulcerative Colitis: A Meta-analysis of Population-Based Cohort Studies
- (2012) Tine Jess et al. Clinical Gastroenterology and Hepatology
- Incidence and Mortality of Colorectal Adenocarcinoma in Persons With Inflammatory Bowel Disease From 1998 to 2010
- (2012) Lisa J. Herrinton et al. GASTROENTEROLOGY
- IL-6 Trans-Signaling via the Soluble IL-6 Receptor: Importance for the Pro-Inflammatory Activities of IL-6
- (2012) Stefan Rose-John International Journal of Biological Sciences
- IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine
- (2012) Samuel Huber et al. NATURE
- Colonoscopic Polypectomy and Long-Term Prevention of Colorectal-Cancer Deaths
- (2012) Ann G. Zauber et al. NEW ENGLAND JOURNAL OF MEDICINE
- Accumulation of CCR4+ CTLA-4hi FOXP3+CD25hi Regulatory T Cells in Colon Adenocarcinomas Correlate to Reduced Activation of Conventional T Cells
- (2012) Helena Svensson et al. PLoS One
- Ulcerative Colitis-Associated Colorectal Cancer Arises in a Field of Short Telomeres, Senescence, and Inflammation
- (2011) R. A. Risques et al. CANCER RESEARCH
- Involvement of interleukin-21 in the regulation of colitis-associated colon cancer
- (2011) Carmine Stolfi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Chromosomal Instability Pathway in Colon Cancer
- (2010) Maria S. Pino et al. GASTROENTEROLOGY
- STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors
- (2010) Heehyoung Lee et al. NATURE MEDICINE
- gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis
- (2009) Julia Bollrath et al. CANCER CELL
- Persistently Activated Stat3 Maintains Constitutive NF-κB Activity in Tumors
- (2009) Heehyoung Lee et al. CANCER CELL
- IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer
- (2009) Sergei Grivennikov et al. CANCER CELL
- Essential Roles of IL-6 Trans-Signaling in Colonic Epithelial Cells, Induced by the IL-6/Soluble-IL-6 Receptor Derived from Lamina Propria Macrophages, on the Development of Colitis-Associated Premalignant Cancer in a Murine Model
- (2009) S. Matsumoto et al. JOURNAL OF IMMUNOLOGY
- Treatment of Active Crohn's Disease With MLN0002, a Humanized Antibody to the α4β7 Integrin
- (2008) Brian G. Feagan et al. Clinical Gastroenterology and Hepatology
- Regulation of Gut Inflammation and Th17 Cell Response by Interleukin-21
- (2008) Daniele Fina et al. GASTROENTEROLOGY
- Regulation of inflammatory responses by IL-17F
- (2008) Xuexian O. Yang et al. JOURNAL OF EXPERIMENTAL MEDICINE
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