Recent advances and prospects of hyaluronan as a multifunctional therapeutic system
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Title
Recent advances and prospects of hyaluronan as a multifunctional therapeutic system
Authors
Keywords
Hyaluronic acid, Low and high molecular weight HA, Drug delivery, Inflammation, Immunity, Cancer
Journal
JOURNAL OF CONTROLLED RELEASE
Volume 336, Issue -, Pages 598-620
Publisher
Elsevier BV
Online
2021-07-05
DOI
10.1016/j.jconrel.2021.07.002
References
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- (2021) Can Lei et al. JOURNAL OF CONTROLLED RELEASE
- Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer
- (2019) James B. Wing et al. IMMUNITY
- Hyaluronan: molecular size‐dependent signaling and biological functions in inflammation and cancer
- (2019) Anastasia G. Tavianatou et al. FEBS Journal
- Raloxifene-encapsulated hyaluronic acid-decorated chitosan nanoparticles selectively induce apoptosis in lung cancer cells
- (2019) Fahad M. Almutairi et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Catalase-Integrated Hyaluronic Acid as Nanocarriers for Enhanced Photodynamic Therapy in Solid Tumor
- (2019) Soo Zeng Fiona Phua et al. ACS Nano
- Defects in intervertebral disc and spine during development, degeneration, and pain: New research directions for disc regeneration and therapy
- (2019) Sarthak Mohanty et al. Wiley Interdisciplinary Reviews-Developmental Biology
- Hyaluronan hydrogels delivering BMP-6 for local targeting of malignant plasma cells and osteogenic differentiation of mesenchymal stromal cells
- (2019) Anna Luise Grab et al. Acta Biomaterialia
- A novel low molecular weight nanocomposite hydrogel formulation for intra-tumoural delivery of anti-cancer drugs
- (2019) Ivana Štaka et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Redox-Responsive and Dual-Targeting Hyaluronic Acid–Methotrexate Prodrug Self-Assembling Nanoparticles for Enhancing Intracellular Drug Self-Delivery
- (2019) Yubin Zhang et al. MOLECULAR PHARMACEUTICS
- Biomedical Applications of Hyaluronic Acid-Based Nanomaterials in Hyperthermic Cancer Therapy
- (2019) Subin Kim et al. Pharmaceutics
- Hyaluronic Acid: Molecular Mechanisms and Therapeutic Trajectory
- (2019) Ramesh C. Gupta et al. Frontiers in Veterinary Science
- Hyaluronic acid for advanced therapies: Promises and challenges
- (2019) Nunzia Gallo et al. EUROPEAN POLYMER JOURNAL
- Hyaluronic acid–bilirubin nanomedicine for targeted modulation of dysregulated intestinal barrier, microbiome and immune responses in colitis
- (2019) Yonghyun Lee et al. NATURE MATERIALS
- Lysosomes as a therapeutic target
- (2019) Srinivasa Reddy Bonam et al. NATURE REVIEWS DRUG DISCOVERY
- An Orally Administrated Hyaluronan Functionalized Polymeric Hybrid Nanoparticle System for Colon-Specific Drug Delivery
- (2019) Niranjan G. Kotla et al. Nanomaterials
- Hyaluronic Acid Synthesis Contributes to Tissue Damage in Systemic Lupus Erythematosus
- (2019) Abel Suarez-Fueyo et al. Frontiers in Immunology
- Pemetrexed-conjugated hyaluronan for the treatment of malignant pleural mesothelioma
- (2019) Yuki Amano et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Efficacy of instillation treatment with hyaluronic acid in relieving symptoms in patients with BPS/IC and uncomplicated recurrent urinary tract infections - Long-term results of a multicenter study
- (2019) Ioan Scarneciu et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Self-assembled hyaluronan nanocapsules for the intracellular delivery of anticancer drugs
- (2019) Ana Cadete et al. Scientific Reports
- For antigen-specific effector or Foxp3+ regulatory T cell fate, cyclin-dependent kinases hold the trump card
- (2019) Srinivasa Reddy Bonam et al. Cellular & Molecular Immunology
- Bioresponsive drug delivery systems in intestinal inflammation: State-of-the-art and future perspectives
- (2018) Niranjan G. Kotla et al. ADVANCED DRUG DELIVERY REVIEWS
- Hyaluronic acid in dermatomyositis and polymyositis: relationship with disease and cutaneous lesions
- (2018) Marilda Guimarães Silva et al. ANAIS BRASILEIROS DE DERMATOLOGIA
- Hyaluronic acid coated albumin nanoparticles for targeted peptide delivery in the treatment of retinal ischaemia
- (2018) Di Huang et al. BIOMATERIALS
- Effect of hyaluronic acid hydrogels containing astrocyte-derived extracellular matrix and/or V2a interneurons on histologic outcomes following spinal cord injury
- (2018) Russell E. Thompson et al. BIOMATERIALS
- Synthesis of novel grafted hyaluronic acid with antitumor activity
- (2018) Mahmoud H. Abu Elella et al. CARBOHYDRATE POLYMERS
- One-pot synthesis of dopamine-conjugated hyaluronic acid/polydopamine nanocomplexes to control protein drug release
- (2018) Dae Gon Lim et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Comparaison de la qualité de vision objective mesurée par aberrométrie double passage chez des patients atteints de syndrome sec modéré : larmes artificielles versus sérum physiologique : une étude pilote
- (2018) G. Vandermeer et al. JOURNAL FRANCAIS D OPHTALMOLOGIE
- Layilin is critical for mediating hyaluronan 35 kDa-induced intestinal epithelial tight junction protein ZO-1 in vitro and in vivo
- (2018) Yeojung Kim et al. MATRIX BIOLOGY
- Regulation of hyaluronan biosynthesis and clinical impact of excessive hyaluronan production
- (2018) Paraskevi Heldin et al. MATRIX BIOLOGY
- Hyaluronic Acid in the Third Millennium
- (2018) Arianna Fallacara et al. Polymers
- Implantation of hyaluronic acid hydrogel prevents the pain phenotype in a rat model of intervertebral disc injury
- (2018) Isma Liza Mohd Isa et al. Science Advances
- Autophagy: A new concept in autoimmunity regulation and a novel therapeutic option
- (2018) Srinivasa Reddy Bonam et al. JOURNAL OF AUTOIMMUNITY
- Hyaluronic acid (hyaluronan): a review
- (2018) J. Necas et al. VETERINARNI MEDICINA
- HA/HSA co-modified erlotinib–albumin nanoparticles for lung cancer treatment
- (2018) Yuzhou Shen et al. Drug Design Development and Therapy
- Neuroinflammatory mechanisms of blood-brain barrier damage in ischemic stroke
- (2018) Changjun Yang et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Comparison Between Viscous Teardrops and Saline Solution to Fill Orthokeratology Contact Lenses Before Overnight Wear
- (2017) Gonzalo Carracedo et al. Eye & Contact Lens-Science and Clinical Practice
- Hyaluronic Acid Coated Albumin Nanoparticles for Targeted Peptide Delivery to the Retina
- (2017) Di Huang et al. MOLECULAR PHARMACEUTICS
- Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis
- (2017) Bo Xiao et al. MOLECULAR THERAPY
- Combined Treatment with Hyaluronic Acid and Mesalamine Protects Rats from Inflammatory Bowel Disease Induced by Intracolonic Administration of Trinitrobenzenesulfonic Acid
- (2017) Chih-Tung Chiu et al. MOLECULES
- Novel Artificial Tears Containing Cross-Linked Hyaluronic Acid: An In Vitro Re-Epithelialization Study
- (2017) Arianna Fallacara et al. MOLECULES
- The survival of fetal and bone marrow monocyte-derived alveolar macrophages is promoted by CD44 and its interaction with hyaluronan
- (2017) Y Dong et al. Mucosal Immunology
- Hyaluronidase 2 Deficiency Causes Increased Mesenchymal Cells, Congenital Heart Defects, and Heart FailureCLINICAL PERSPECTIVE
- (2017) Biswajit Chowdhury et al. Circulation-Cardiovascular Genetics
- Biomimetic Lipid-Based Nanosystems for Enhanced Dermal Delivery of Drugs and Bioactive Agents
- (2017) Niranjan G. Kotla et al. ACS Biomaterials-Science & Engineering
- Biomimetic Lipid-Based Nanosystems for Enhanced Dermal Delivery of Drugs and Bioactive Agents
- (2017) Niranjan G. Kotla et al. ACS Biomaterials Science & Engineering
- Multivalent hyaluronic acid bioconjugates improve sFlt-1 activity in vitro
- (2016) Eda I. Altiok et al. BIOMATERIALS
- Multifunctional Click Hyaluronic Acid Nanogels for Targeted Protein Delivery and Effective Cancer Treatment in Vivo
- (2016) Jing Chen et al. CHEMISTRY OF MATERIALS
- Hyaluronic acid-coated liposomes for targeted delivery of paclitaxel, in-vitro characterization and in-vivo evaluation
- (2016) Fatemeh Ravar et al. JOURNAL OF CONTROLLED RELEASE
- Hyaluronic acid scaffold has a neuroprotective effect in hemisection spinal cord injury
- (2016) Sergiy V. Kushchayev et al. JOURNAL OF NEUROSURGERY-SPINE
- Dual-targeting hybrid nanoparticles for the delivery of SN38 to Her2 and CD44 overexpressed human gastric cancer
- (2016) Zhe Yang et al. Nanoscale
- Combination Therapy for Ulcerative Colitis: Orally Targeted Nanoparticles Prevent Mucosal Damage and Relieve Inflammation
- (2016) Bo Xiao et al. Theranostics
- Intra-articular use of hyaluronic acid in the treatment of osteoarthritis
- (2016) Alberto Migliore Clinical Interventions in Aging
- Review of long-term adverse effects associated with the use of chemically-modified animal and nonanimal source hyaluronic acid dermal fillers
- (2016) Paul Edwards Clinical Interventions in Aging
- Hyaluronic acid decreases IL-6 and IL-8 secretion and permeability in an inflammatory model of interstitial cystitis
- (2015) Peadar Rooney et al. Acta Biomaterialia
- Hyaluronic Acid Based Hydrogels Attenuate Inflammatory Receptors and Neurotrophins in Interleukin-1β Induced Inflammation Model of Nucleus Pulposus Cells
- (2015) Isma Liza Mohd Isa et al. BIOMACROMOLECULES
- Enhancing neural stem cell response to SDF-1α gradients through hyaluronic acid-laminin hydrogels
- (2015) C.P. Addington et al. BIOMATERIALS
- Aptamer decorated hyaluronan/chitosan nanoparticles for targeted delivery of 5-fluorouracil to MUC1 overexpressing adenocarcinomas
- (2015) Zahra Ghasemi et al. CARBOHYDRATE POLYMERS
- Hyaluronic acid targeting of CD44 for cancer therapy: from receptor biology to nanomedicine
- (2015) George Mattheolabakis et al. JOURNAL OF DRUG TARGETING
- Click-crosslinked injectable hyaluronic acid hydrogel is safe and biocompatible in the intrathecal space for ultimate use in regenerative strategies of the injured spinal cord
- (2015) T. Führmann et al. METHODS
- Interactions of Hyaluronic Acid with the Skin and Implications for the Dermal Delivery of Biomacromolecules
- (2015) Madeleine Witting et al. MOLECULAR PHARMACEUTICS
- A hyaluronic acid nanogel for photo–chemo theranostics of lung cancer with simultaneous light-responsive controlled release of doxorubicin
- (2015) Zehedina Khatun et al. Nanoscale
- Stem cell therapy for intervertebral disc regeneration: obstacles and solutions
- (2015) Daisuke Sakai et al. Nature Reviews Rheumatology
- Up-regulation of CD44 in the development of metastasis, recurrence and drug resistance of ovarian cancer
- (2015) Yan Gao et al. Oncotarget
- The Where, When, How, and Why of Hyaluronan Binding by Immune Cells
- (2015) Sally S. M. Lee-Sayer et al. Frontiers in Immunology
- Lipid Raft-Mediated Regulation of Hyaluronan–CD44 Interactions in Inflammation and Cancer
- (2015) Toshiyuki Murai Frontiers in Immunology
- The Content and Size of Hyaluronan in Biological Fluids and Tissues
- (2015) Mary K. Cowman et al. Frontiers in Immunology
- Key Roles of Hyaluronan and Its CD44 Receptor in the Stemness and Survival of Cancer Stem Cells
- (2015) Theerawut Chanmee et al. Frontiers in Oncology
- Peritoneal Adhesion and Angiogenesis in Ovarian Carcinoma Are Inversely Regulated by Hyaluronan: The Role of Gonadotropins
- (2015) Yael Chagit Tzuman et al. NEOPLASIA
- Delivery of iPS-NPCs to the Stroke Cavity within a Hyaluronic Acid Matrix Promotes the Differentiation of Transplanted Cells
- (2014) Jonathan Lam et al. ADVANCED FUNCTIONAL MATERIALS
- Hyaluronan: Biosynthesis and signaling
- (2014) Davide Vigetti et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Chemoenzymatic Synthesis of Oligohyaluronan–Lipid Conjugates
- (2014) Dipali Ruhela et al. BIOCONJUGATE CHEMISTRY
- A hydrogel-based tumor model for the evaluation of nanoparticle-based cancer therapeutics
- (2014) Xian Xu et al. BIOMATERIALS
- Highly sensitive and selective anticancer effect by conjugated HA-cisplatin in non-small cell lung cancer overexpressed with CD44
- (2014) Yu Hua Quan et al. EXPERIMENTAL LUNG RESEARCH
- Galectin-9-CD44 Interaction Enhances Stability and Function of Adaptive Regulatory T Cells
- (2014) Chuan Wu et al. IMMUNITY
- Facts, fallacies and future of dissolution testing of polysaccharide based colon-specific drug delivery
- (2014) Niranjan Goud Kotla et al. JOURNAL OF CONTROLLED RELEASE
- Degradable Hyaluronic Acid/Protamine Sulfate Interpolyelectrolyte Complexes as miRNA-Delivery Nanocapsules for Triple-Negative Breast Cancer Therapy
- (2014) Shihua Wang et al. Advanced Healthcare Materials
- Glioblastoma Behaviors in Three-Dimensional Collagen-Hyaluronan Composite Hydrogels
- (2013) Shreyas S. Rao et al. ACS Applied Materials & Interfaces
- Dermal Distribution of Hyaluronan in Psoriatic Arthritis; Coexistence of CD44, MMP3 and 9
- (2013) U Lindqvist et al. ACTA DERMATO-VENEREOLOGICA
- Hyaluronic acid-coated liposomes for active targeting of gemcitabine
- (2013) Silvia Arpicco et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Hypotheses on the evolution of hyaluronan: A highly ironic acid
- (2013) A. B. Csoka et al. GLYCOBIOLOGY
- The Hyaluronan Receptor for Endocytosis (HARE) Activates NF-κB-mediated Gene Expression in Response to 40–400-kDa, but Not Smaller or Larger, Hyaluronans
- (2013) Madhu S. Pandey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Human Milk Hyaluronan Enhances Innate Defense of the Intestinal Epithelium
- (2013) David R. Hill et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Role of cytokines in intervertebral disc degeneration: pain and disc content
- (2013) Makarand V. Risbud et al. Nature Reviews Rheumatology
- Consecutive Targetable Smart Nanoprobe for Molecular Recognition of Cytoplasmic microRNA in Metastatic Breast Cancer
- (2012) Eunjung Kim et al. ACS Nano
- Multilayered mucoadhesive hydrogel films based on thiolated hyaluronic acid and polyvinylalcohol for insulin delivery
- (2012) J. Ding et al. Acta Biomaterialia
- Intravesical hyaluronic acid for interstitial cystitis/painful bladder syndrome: A comparative randomized assessment of different regimens
- (2012) Ming-Chih Lai et al. INTERNATIONAL JOURNAL OF UROLOGY
- Specific-sized Hyaluronan Fragments Promote Expression of Human β-Defensin 2 in Intestinal Epithelium
- (2012) David R. Hill et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Murine Hyaluronidase 2 Deficiency Results in Extracellular Hyaluronan Accumulation and Severe Cardiopulmonary Dysfunction
- (2012) Biswajit Chowdhury et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The immunology of acute stroke
- (2012) Ángel Chamorro et al. Nature Reviews Neurology
- Regulation of Antigen-Experienced T Cells: Lessons from the Quintessential Memory Marker CD44
- (2012) Bas J. G. Baaten et al. Frontiers in Immunology
- Hyaluronic Acid Hydrogels for Biomedical Applications
- (2011) Jason A. Burdick et al. ADVANCED MATERIALS
- Hyaluronan reduces inflammation in experimental arthritis by modulating TLR-2 and TLR-4 cartilage expression
- (2011) Giuseppe M. Campo et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Effectiveness of Artificial Tears in the Management of Evaporative Dry Eye
- (2011) Louise C McCann et al. CORNEA
- Identification and Molecular Analysis of Glycosaminoglycans in Cutaneous Lupus Erythematosus and Dermatomyositis
- (2011) Laura M. Chang et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- CD44 Reciprocally Regulates the Differentiation of Encephalitogenic Th1/Th17 and Th2/Regulatory T Cells through Epigenetic Modulation Involving DNA Methylation of Cytokine Gene Promoters, Thereby Controlling the Development of Experimental Autoimmune Encephalomyelitis
- (2011) H. Guan et al. JOURNAL OF IMMUNOLOGY
- Measurement of an adhesion molecule as an indicator of inflammatory disease activity: Up-regulation of the receptor for hyaluronate (CD44) in rheumatoid arthritis
- (2010) Barton F. Haynes et al. ARTHRITIS AND RHEUMATISM
- The effects of hyaluronic acid hydrogels with tunable mechanical properties on neural progenitor cell differentiation
- (2010) Stephanie K. Seidlits et al. BIOMATERIALS
- The effect of molecular weight on the biodistribution of hyaluronic acid radiolabeled with111In after intravenous administration to rats
- (2010) E. Svanovsky et al. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
- Inducible macropinocytosis of hyaluronan in B16-F10 melanoma cells
- (2010) Henry J. Greyner et al. MATRIX BIOLOGY
- The role of intra-articular hyaluronan (Sinovial®) in the treatment of osteoarthritis
- (2010) Antonio Gigante et al. RHEUMATOLOGY INTERNATIONAL
- A Multicenter, Randomized, Double-blind, Parallel Group Pilot Evaluation of the Efficacy and Safety of Intravesical Sodium Chondroitin Sulfate Versus Vehicle Control in Patients With Interstitial Cystitis/Painful Bladder Syndrome
- (2010) J. Curtis Nickel et al. UROLOGY
- Development of hyaluronic acid-based scaffolds for brain tissue engineering
- (2009) Tzu-Wei Wang et al. Acta Biomaterialia
- Hyaluronic acid hydrogel loaded with genetically-engineered brain-derived neurotrophic factor as a neural cell carrier
- (2009) Tadashi Nakaji-Hirabayashi et al. BIOMATERIALS
- Role, Metabolism, Chemical Modifications and Applications of Hyaluronan
- (2009) Nicola Volpi et al. CURRENT MEDICINAL CHEMISTRY
- Regulation of Colonic Epithelial Repair in Mice by Toll-Like Receptors and Hyaluronic Acid
- (2009) Ling Zheng et al. GASTROENTEROLOGY
- Target specific and long-acting delivery of protein, peptide, and nucleotide therapeutics using hyaluronic acid derivatives
- (2009) Eun Ju Oh et al. JOURNAL OF CONTROLLED RELEASE
- Intact extracellular matrix and the maintenance of immune tolerance: high molecular weight hyaluronan promotes persistence of induced CD4+CD25+ regulatory T cells
- (2009) Paul L. Bollyky et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Self-assembled hyaluronic acid nanoparticles as a potential drug carrier for cancer therapy: synthesis, characterization, and in vivo biodistribution
- (2009) Ki Young Choi et al. JOURNAL OF MATERIALS CHEMISTRY
- Viability and differentiation of neural precursors on hyaluronic acid hydrogel scaffold
- (2009) Linjie Pan et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Hyaluronic acid inhibits the glial scar formation after brain damage with tissue loss in rats
- (2009) Chien-Min Lin et al. SURGICAL NEUROLOGY
- Kinetics of Hyaluronan Hydrolysis in Acidic Solution at Various pH Values
- (2008) Kristoffer Tømmeraas et al. BIOMACROMOLECULES
- Regulatory T Cells and Immune Tolerance
- (2008) Shimon Sakaguchi et al. CELL
- Absorption, Uptake and Tissue Affinity of High-Molecular-Weight Hyaluronan after Oral Administration in Rats and Dogs
- (2008) Lajos Balogh et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Effect of a new cohesive ophthalmic viscosurgical device on corneal protection and intraocular pressure in small-incision cataract surgery
- (2008) Thomas Neumayer et al. JOURNAL OF CATARACT AND REFRACTIVE SURGERY
- An injectable hyaluronic acid–tyramine hydrogel system for protein delivery
- (2008) Fan Lee et al. JOURNAL OF CONTROLLED RELEASE
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